Increasing the Ability of Children with Autism in Performing Oral Hygiene Through Photographs: a Single Subject Study in Indonesia

Autism is a developmental disorder in children that now affects 1 : 88 children in the world. As many as 50% of school-age children with autism face difficulty in independently performing oral hygiene. This research seeks to increase the ability of children with autism in performing oral hygiene through the use of photographs. The methodology of the research is quantitative quasi-experimental through the single subject design. The three research subjects are school-age children with autism, and their parents also participated in this research. Intervention is conducted through a series of photographs on the steps in performing oral hygiene after the ability trend in the baseline phase is observed. Assessment in the ability of performing oral hygiene is done in the baseline, intervention, maintenance, and generalization phases. The result is that the ability to perform oral hygiene for Children A, B, and C increases from 14, 21, and 22 to 30, 31, and 30. The ability to perform oral hygiene for the three children increases after intervention and settles in the generalization phase

Increased relapse rate during COVID-19 lockdown in an Italian cohort of children with juvenile idiopathic arthritis.

Objectives: Changes of routine disease management associated with COVID-19 lockdown might have potentially affected the clinical course of juvenile idiopathic arthritis (JIA). Aim of our study was to assess the rate of disease flare before and during COVID-19 lockdown to investigate its impact on disease course in JIA children. Methods: A single-center retrospective study was conducted, including patients presenting inactive JIA between September 1st , 2018 and March 9th , 2019 (group A) and between September 1st , 2019 and March 9th , 2020 (group B). For each patient, demographic and clinical data were collected. The rate of JIA flare from March 10th , 2019 to June 30th , 2019 for group A and from March 10th , 2020 to June 30th , 2020 for group B was compared. Results: Group A included 126 patients and group B 124 patients. Statistical analysis did not show significant differences among the two cohorts with respect to age, sex, age of JIA onset, JIA subtype, co-occurrence of uveitis, ANA positivity and past or ongoing medications. The rate of disease flare during lockdown at time of first COVID-19 pandemic wave, was significantly higher in comparison to the previous year (16.9% vs 6.3%, p=0.009). Conclusion: Our study showed that COVID-19 lockdown was associated with a higher rate of joint inflammation in JIA children. This finding has a considerable clinical implication, since restrictive measures may be necessary in order to contain pandemics. Our data highlight the need for rearrangement in the home and healthcare management of JIA children during lockdowns

Off-design of a CO2-based mixture transcritical cycle for CSP applications: Analysis at part load and variable ambient temperature

This work focuses on the off-design analysis of a simple recuperative transcritical power cycle working with the CO2 + C6F6 mixture as working fluid. The cycle is aircooled and proposed for a state-of-the-art concentrated solar plant with solar salts as heat transfer fluid in a hot region, with a cycle minimum and maximum temperature of 51 degrees C and 550 degrees C at design conditions. The design of each cycle heat exchanger (primary, recuperator and condenser) is carried out in MATLAB with referenced models and the turbine designed in CFD, providing performance maps adopted by the cycle operating in sliding pressure. The off-design of the cycle is developed with a routine simulating the thermodynamic conditions of the cycle at variable ambient temperature and thermal inputs down to 40 % of the nominal value. The results show that the cycle can efficiently run in a wide range of part load conditions and ambient temperatures, from around 0 degrees C to over 40 degrees C, with net electric cycle efficiencies from 45 % to 36 %: according to the control philosophy proposed, the condenser fans are fixed at design speed, while the cycle operates in sliding pressure, when is possible. The results evidence the flexibility and good performances of the proposed system in various operating conditions

Cohort 2013 Four-Year Graduation Rates -- State Results

From September 2016-April 2017, Am Timan, Chad, experienced a large HEV outbreak in an urban setting with a limited impact in terms of morbidity and mortality. To better understand HEV epidemiology in this context, we estimated the seroprevalence of anti-HEV antibodies (IgM and IgG) and assessed the risk factors for recent HEV infections (positive anti-HEV IgM) during this outbreak

MULTIPLE ORGAN HARVESTING: EVOLUTION OF SURGICAL TECHNIQUE. PERSONAL EXPERIENCE

SINCE 1950, kidney, liver, heart, and lung transplantations have dramatically improved, emerging as the elective treatment modality for organ failure. Nevertheless, the indications to pancreas and bowel grafting are stili controversial. Several factors have contributed such results, namely the introduction of cyclosporine (CyA) in 1981, the use of new solutions for solid organ preservation (eg, the University of Wisconsin solution), the improvement in donor selection criteria, intensive care, as well as improvement management of transplant operation and harvesting surgical technique

The Italian Response to the COVID-19 Crisis: Lessons Learned and Future Direction in Social Development:

Against the backdrop of a continuously changing situation, the aim of this paper is to discuss the impact of COVID-19 crisis in Italy, the government response to cope with the crisis and the major lessons learned during its management. The analysis shows how Italy's response has been characterised by some rapid measures to tackle the health crisis, but few plans in the mitigation stage and a lack of community involvement. This contribution stress the importance of a cultural shift, through the effort to apply in practice the principles already indicated in the main global policy frameworks to guide disaster management. A community social development approach can help to build concrete actions in this direction