Teacher education for inclusive practice – Responding to policy

This article draws on research on the way in one teacher education in England and examines the ways in which the programme prepares student-teachers for inclusive practice in science teaching. We frame our analysis by drawing on aspects of institutional mediation of official policy in teacher education programmes, we need pedagogies of praxis that move beyond (and sometimes against) the official policy definitions of inclusion, and draw instead on a more critical approach to the formation of future professionals.http://www.tandfonline.com/doi/full/10.1080/02619768.2015.1031338http://www.tandfonline.com/doi/full/10.1080/02619768.2015.103133

Cardiac Autonomic Function Correlates with Arterial Stiffness in the Early Stage of Type 1 Diabetes

Arterial stiffness is increased in type 1 diabetes (T1D), before any clinical complications of the disease are evident. The aim of the present paper was to investigate the association between cardiac autonomic function and arterial stiffness in a cohort of young T1D patients, without history of hypertension and any evidence of macrovascular and/or renal disease. Large artery stiffness was assessed by measurement of carotid-femoral pulse wave velocity (PWV). Cardiac autonomic function was assessed by the cardiovascular tests proposed by Ewing and Clarke. Patients with a high cardiac autonomic neuropathy score (≥4) had significantly higher PWV than those with a low score (0-1). A negative, heart rate-independent, correlation between PWV and heart rate variation during respiration was observed (r = −0.533,  P < 0.001). In multivariable analysis, E/I index was the strongest correlate of PWV (β-coefficient = −0.326, P = 0.002). Cardiac parasympathetic function is a strong predictor of large arterial stiffness, in young T1D patients free of macrovascular and renal complications

Arterial stiffness is inversely related to plasma adiponectin levels in young normotensive patients with type 1 diabetes

OBJECTIVE This study investigated the association between arterial stiffness and plasma adiponectin in patients with type 1 diabetes. RESEARCH DESIGN AND METHODS Participants were normotensive patients with type 1 diabetes who were up to age 40 years. Subjects on statins with macrovascular disease or overt nephropathy were excluded. Large artery stiffness was assessed by measurement of carotid-femoral pulse wave velocity (PWV), whereas plasma adiponectin was measured by radioimmunoassay. RESULTS Data from 80 patients (age 27.1 ± 6.1 years, BMI 24.2 ± 3.1 kg/m2, HbA1c 7.5 ± 1.6%, 39 men, adiponectin 13.9 ± 6.7 μg/mL, and PWV 5.6 ± 0.9 m/s) were analyzed. Log adiponectin inversely correlated with age-adjusted PWV (r = −0.291, P = 0.009) and waist circumference (r = −0.427, P < 0.001). In a fully adjusted model, age, expiration/inspiration index, and log adiponectin were independently associated with PWV, explaining 39.6% of its variance. CONCLUSIONS Arterial stiffness is inversely related to adiponectin concentration in young patients with type 1 diabetes without major complications

Topic Strategies and the Internal Structure of Nominal Arguments in Greek and Italian

In this article, we argue that a set of unexpected contrasts in the interpretation of clitic-left-dislocated indefinites in Greek and Italian derive from structural variation in the nominal syntax of the two languages. Greek resists nonreferential indefinites in clitic left-dislocation, resorting to the topicalization of an often bare noun for nonreferential topics. By contrast, clitic left-dislocation is employed in Italian for topics regardless of their definite/indefinite interpretation. We argue that this contrast is directly linked to the wide availability of bare nouns in Greek, which stems from a structural difference in the nominal syntax of the two languages. In particular, we hypothesize that Greek nominal arguments lack a D layer. Rather, they are Number Phrases. We situate this analysis in the context of Chierchia’s (1998) typology of nominals. We argue that, on a par with Italian nouns, Greek nouns are [−arg, +pred]. However, they do not employ a syntactic head (D) for type-shifting to e . Rather, they resort to covert type-shifting, a hypothesis that is necessary to account for the distribution and interpretations of bare nouns in Greek, vis-à-vis other [−arg, +pred] languages like Italian and French. </jats:p

On the Topic of Pseudoclefts

This paper presents arguments in favor of a pseudocleft analysis of a certain class of sentences in Malagasy, despite the lack of an overt wh-element. It is shown that voice morphology on the verb creates an operator-variable relationship much like the one created by wh-movement in free relatives in English and other languages. The bulk of the paper argues in favor of an inversion analysis of specificational pseudoclefts in Malagasy: a predicate DP is fronted to a topic position from within a small clause constituent. Moreover, it is shown that the same inversion occurs in equative and specificational sentences in Malagasy, which suggests that these types of sentences share the same syntactic structure. The proposed analysis also provides support for the view that specificational pseudoclefts have a topic \u3e focus structure, where the wh-clause has been overtly topicalized

One step closer to understanding the role of bacteria in diabetic foot ulcers: characterising the microbiome of ulcers

Background: The aim of this study was to characterise the microbiome of new and recurrent diabetic foot ulcers using 16S amplicon sequencing (16S AS), allowing the identification of a wider range of bacterial species that may be important in the development of chronicity in these debilitating wounds. Twenty patients not receiving antibiotics for the past three months were selected, with swabs taken from each individual for culture and 16S AS. DNA was isolated using a combination of bead beating and kit extraction. Samples were sequenced on the Illumina Hiseq 2500 platform. Results: Conventional laboratory culture showed positive growth from only 55 % of the patients, whereas 16S AS was positive for 75 % of the patients (41 unique genera, representing 82 different operational taxonomic units (OTU’s). S. aureus was isolated in 72 % of culture-positive samples, whereas the most commonly detected bacteria in all ulcers were Peptoniphilusspp., Anaerococcus spp. and Corynebacterium spp., with the addition of Staphylococcus spp. in new ulcers. The majority of OTU’s residing in both new and recurrent ulcers (over 67 %) were identified as facultative or strict anaerobic Gram-positive organisms. Principal component analysis (PCA) showed no difference in clustering between the two groups (new and recurrent ulcers). Conclusions: The abundance of anaerobic bacteria has important implications for treatment as it suggests that the microbiome of each ulcer “starts afresh” and that, although diverse, are not distinctly different from one another with respect to new or recurrent ulcers. Therefore, when considering antibiotic therapy the duration of current ulceration may be a more important consideration than a history of healed ulcer

Change-of-state Paradigms and the middle in Kinyarwanda

This paper investigates the derivational relationships among members of verbal paradigms in Kinyarwanda (Bantu JD.61; Rwanda) by pursuing two interrelated goals. First, I describe a variety of derivational strategies for marking transitive and intransitive variants in change-of-state verb paradigms. Second, I focus on the detransitivizing morpheme –ik which serves as one possible marking for intransitive members of these paradigms. Ultimately, I argue that this morpheme is a marker of middle voice, and the variety of readings which appear with this form can be subsumed under a single operation of argument suppression. Finally, I provide a discussion of reflexives and the apparent lack of a reflexive reading with –ik by arguing that this reading is blocked by either lexical reflexives or the reflexive prefix i–

Lexical deconstruction—review of Giegerich, H., Lexical structures: Compounding and the modules of grammar, Edinburgh Studies in Theoretical Linguistics, vol. 1

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