92 research outputs found
Internalized transphobia predicts worse longitudinal trend of body uneasiness in transgender persons treated with gender affirming hormone therapy: a 1-year follow-up study
MID-TERM CLINICAL OUTCOME OF CATANIA™ CORONARY STENT SYSTEM WITH NANOTHIN POLYZENE®-F IN A REAL WORLD UNSELECTED POPULATION: PRELIMINARY RESULTS: I2 POSTER CONTRIBUTIONS
Cardiovascular magnetic resonance for the assessment of patients undergoing transcatheter aortic valve implantation: a pilot study
<p>Abstract</p> <p>Background</p> <p>Before trans-catheter aortic valve implantation (TAVI), assessment of cardiac function and accurate measurement of the aortic root are key to determine the correct size and type of the prosthesis. The aim of this study was to compare cardiovascular magnetic resonance (CMR) and trans-thoracic echocardiography (TTE) for the assessment of aortic valve measurements and left ventricular function in high-risk elderly patients submitted to TAVI.</p> <p>Methods</p> <p>Consecutive patients with severe aortic stenosis and contraindications for surgical aortic valve replacement were screened from April 2009 to January 2011 and imaged with TTE and CMR.</p> <p>Results</p> <p>Patients who underwent both TTE and CMR (n = 49) had a mean age of 80.8 ± 4.8 years and a mean logistic EuroSCORE of 14.9 ± 9.3%. There was a good correlation between TTE and CMR in terms of annulus size (R<sup>2 </sup>= 0.48, p < 0.001), left ventricular outflow tract (LVOT) diameter (R<sup>2 </sup>= 0.62, p < 0.001) and left ventricular ejection fraction (LVEF) (R<sup>2 </sup>= 0.47, p < 0.001) and a moderate correlation in terms of aortic valve area (AVA) (R<sup>2 </sup>= 0.24, p < 0.001). CMR generally tended to report larger values than TTE for all measurements. The Bland-Altman test indicated that the 95% limits of agreement between TTE and CMR ranged from -5.6 mm to + 1.0 mm for annulus size, from -0.45 mm to + 0.25 mm for LVOT, from -0.45 mm<sup>2 </sup>to + 0.25 mm<sup>2 </sup>for AVA and from -29.2% to 13.2% for LVEF.</p> <p>Conclusions</p> <p>In elderly patients candidates to TAVI, CMR represents a viable complement to transthoracic echocardiography.</p
Implementation and performances of the IPbus protocol for the JUNO Large-PMT readout electronics
The Jiangmen Underground Neutrino Observatory (JUNO) is a large neutrino
detector currently under construction in China. Thanks to the tight
requirements on its optical and radio-purity properties, it will be able to
perform leading measurements detecting terrestrial and astrophysical neutrinos
in a wide energy range from tens of keV to hundreds of MeV. A key requirement
for the success of the experiment is an unprecedented 3% energy resolution,
guaranteed by its large active mass (20 kton) and the use of more than 20,000
20-inch photo-multiplier tubes (PMTs) acquired by high-speed, high-resolution
sampling electronics located very close to the PMTs. As the Front-End and
Read-Out electronics is expected to continuously run underwater for 30 years, a
reliable readout acquisition system capable of handling the timestamped data
stream coming from the Large-PMTs and permitting to simultaneously monitor and
operate remotely the inaccessible electronics had to be developed. In this
contribution, the firmware and hardware implementation of the IPbus based
readout protocol will be presented, together with the performances measured on
final modules during the mass production of the electronics
Mass testing of the JUNO experiment 20-inch PMTs readout electronics
The Jiangmen Underground Neutrino Observatory (JUNO) is a multi-purpose,
large size, liquid scintillator experiment under construction in China. JUNO
will perform leading measurements detecting neutrinos from different sources
(reactor, terrestrial and astrophysical neutrinos) covering a wide energy range
(from 200 keV to several GeV). This paper focuses on the design and development
of a test protocol for the 20-inch PMT underwater readout electronics,
performed in parallel to the mass production line. In a time period of about
ten months, a total number of 6950 electronic boards were tested with an
acceptance yield of 99.1%
Validation and integration tests of the JUNO 20-inch PMTs readout electronics
The Jiangmen Underground Neutrino Observatory (JUNO) is a large neutrino
detector currently under construction in China. JUNO will be able to study the
neutrino mass ordering and to perform leading measurements detecting
terrestrial and astrophysical neutrinos in a wide energy range, spanning from
200 keV to several GeV. Given the ambitious physics goals of JUNO, the
electronic system has to meet specific tight requirements, and a thorough
characterization is required. The present paper describes the tests performed
on the readout modules to measure their performances.Comment: 20 pages, 13 figure
Potential of Core-Collapse Supernova Neutrino Detection at JUNO
JUNO is an underground neutrino observatory under construction in Jiangmen, China. It uses 20kton liquid scintillator as target, which enables it to detect supernova burst neutrinos of a large statistics for the next galactic core-collapse supernova (CCSN) and also pre-supernova neutrinos from the nearby CCSN progenitors. All flavors of supernova burst neutrinos can be detected by JUNO via several interaction channels, including inverse beta decay, elastic scattering on electron and proton, interactions on C12 nuclei, etc. This retains the possibility for JUNO to reconstruct the energy spectra of supernova burst neutrinos of all flavors. The real time monitoring systems based on FPGA and DAQ are under development in JUNO, which allow prompt alert and trigger-less data acquisition of CCSN events. The alert performances of both monitoring systems have been thoroughly studied using simulations. Moreover, once a CCSN is tagged, the system can give fast characterizations, such as directionality and light curve
Detection of the Diffuse Supernova Neutrino Background with JUNO
As an underground multi-purpose neutrino detector with 20 kton liquid scintillator, Jiangmen Underground Neutrino Observatory (JUNO) is competitive with and complementary to the water-Cherenkov detectors on the search for the diffuse supernova neutrino background (DSNB). Typical supernova models predict 2-4 events per year within the optimal observation window in the JUNO detector. The dominant background is from the neutral-current (NC) interaction of atmospheric neutrinos with 12C nuclei, which surpasses the DSNB by more than one order of magnitude. We evaluated the systematic uncertainty of NC background from the spread of a variety of data-driven models and further developed a method to determine NC background within 15\% with {\it{in}} {\it{situ}} measurements after ten years of running. Besides, the NC-like backgrounds can be effectively suppressed by the intrinsic pulse-shape discrimination (PSD) capabilities of liquid scintillators. In this talk, I will present in detail the improvements on NC background uncertainty evaluation, PSD discriminator development, and finally, the potential of DSNB sensitivity in JUNO
Terapia corticosteroidea per la sterilità maschile immunologica
Scopo del presente studio è valutare l’efficacia della terapia corticosteroidea sull’oligoastenospermia associata alla presenza di anticorpi antispermatozoo nel liquido seminale. A 9 uomini sono stati somministrati 20 mg/die di prednisolone per i primi 10 giorni del ciclo della partner e
poi 5 mg/die sino al giorno dell’ovulazione. La terapia è stata ripetuta per 6 mesi, sospesa per 6 mesi ed eventualmente, in assenza di gravidanze, ripetuta per altri 6 mesi. Si sono ottenute 6 gravidanze, pari al 66,6% dei
casi. In conclusione questa terapia ciclica steroidea si può considerare efficace nel trattamento di casi selezionati di oligoastenospermia moderata associata
alla presenza di anticorpi antispermatozoo nel liquido seminale
Comparison of different concentration of ropivacaine in spinal anesthesia for vascular surgery
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