Calibration features of information-measuring systems for diagnosing technical condition based on the analysis of the mark image blurring

Background. The necessity of creating diagnostic systems for vibro-loaded objects is shown. Contactless systems have sufficient capabilities to determine the amplitude of vibrations, it is noted that an important part of such systems is the calibration process. The purpose of the study is to improve the accuracy of calibration of vibration displacement meters, develop methods for modeling vibration displacement and estimating errors of measurement conversion Materials and methods. The principle of operation of the dynamic calibration system for measuring vibration displacement is proposed. Results. Modeling using this technique has been carried out. A method for estimating measurement errors of calibration vibration displacement has been developed, justified and illustrated with a specific numerical example. A family of curves has been constructed showing the dependence of the reduced error of the calibration system of vibration displacement measuring instruments on the radius of the calibration round mark for different values of the number of pixels per image of the calibration round mark. Conclusions. A technique for numerical simulation of the process of measuring transformation of the image of a calibration round mark and the trace of its vibrational blur has been developed

Smart management of technologies: predictive maintenance of industrial equipment using wireless sensor networks

International audienceOne of the most important problems of creating new and also modernizing and operating the existing industrial equipment is to provide it with technical diagnostic tools. In modern systems, most diagnostic problems are solved by vibration monitoring methods, and they form the basis of this process. For several years already, when creating new responsible equipment, many manufacturers have completed it with monitoring and diagnostic systems, often integrating them functionally with automatic control systems. This paper discusses the methods of servicing industrial equipment, focusing on predictive maintenance, also known as actual maintenance (maintenance according to the actual technical condition).The rationale for the use of wireless systems for data collection and processing is presented. The principles of constructing wireless sensor networks and the data transmission protocols used to collect statistical information on the state of the elements of industrial equipment, depending on the field of application, are analyzed. The purpose of the study is to substantiate the feasibility of using wireless sensor networks as technical diagnostic tools from both economic and technical points of view. The result is the proposed concept of the predictive maintenance system. The paper substantiates the model of optimization of predic-tive repair using wireless sensor networks. This approach is based on minimizing the costs of maintenance of equipment. The presented concept of a system of predictive maintenance on the basis of sensor networks allows real-time analysis of the state of equipment. The approach allows implementing smart management of technologies in companies for ensuring stability of functioning

Smart management of technologies: predictive maintenance of industrial equipment using wireless sensor networks

International audienceOne of the most important problems of creating new and also modernizing and operating the existing industrial equipment is to provide it with technical diagnostic tools. In modern systems, most diagnostic problems are solved by vibration monitoring methods, and they form the basis of this process. For several years already, when creating new responsible equipment, many manufacturers have completed it with monitoring and diagnostic systems, often integrating them functionally with automatic control systems. This paper discusses the methods of servicing industrial equipment, focusing on predictive maintenance, also known as actual maintenance (maintenance according to the actual technical condition).The rationale for the use of wireless systems for data collection and processing is presented. The principles of constructing wireless sensor networks and the data transmission protocols used to collect statistical information on the state of the elements of industrial equipment, depending on the field of application, are analyzed. The purpose of the study is to substantiate the feasibility of using wireless sensor networks as technical diagnostic tools from both economic and technical points of view. The result is the proposed concept of the predictive maintenance system. The paper substantiates the model of optimization of predic-tive repair using wireless sensor networks. This approach is based on minimizing the costs of maintenance of equipment. The presented concept of a system of predictive maintenance on the basis of sensor networks allows real-time analysis of the state of equipment. The approach allows implementing smart management of technologies in companies for ensuring stability of functioning

New Adamantane-Containing Edaravone Conjugates as Potential Neuroprotective Agents for ALS Treatments

Currently, there are no effective drugs for the treatment of amyotrophic lateral sclerosis (ALS). Only two drugs—edaravone and riluzole—have been approved, but they have very limited efficacy. The aim of this work was to modify the structural core of the Edaravone—phenylpyrazolone moiety and combine it with aminoadamantane pharmacophore in order to expand the spectrum of its action to a number of processes involved in the pathogenesis of ALS. New conjugates of edaravone derivatives with 1-aminoadamantanes combined with alkylene or hydroxypropylene spacers were synthesized, and their biological activity was investigated. Compounds were found that could inhibit lipid peroxidation and calcium-related mitochondrial permeability, block fast sodium currents of CNS neurons, and reduce aggregation of the mutated form of the FUS-protein typical to ALS. So, the proposed modification of the edaravone molecule has allowed the obtaining of new original structures that combine some prospective therapeutic mechanisms against key chains of the pathogenesis of ALS. The identified lead compounds can be used for further optimization and development of new promising drugs on this basis for the treatment of ALS

Synthesis and X‑ray Crystallography of [Mg(H₂O)₆][AnO₂(C₂H₅COO)₃]₂ (An = U, Np, or Pu)

Synthesis and X-ray crystallography of single crystals of [Mg­(H₂O)₆]­[AnO₂(C₂H₅COO)₃]₂, where An = U (<b>I</b>), Np (<b>II</b>), or Pu (<b>III</b>), are reported. Compounds <b>I</b>–<b>III</b> are isostructural and crystallize in the trigonal crystal system. The structures of <b>I</b>–<b>III</b> are built of hydrated magnesium cations [Mg­(H₂O)₆]²⁺ and mononuclear [AnO₂(C₂H₅COO)₃]⁻ complexes, which belong to the AB⁰¹₃ crystallochemical group of uranyl complexes (A = AnO₂²⁺, B⁰¹ = C₂H₅COO^–). Peculiarities of intermolecular interactions in the structures of [Mg­(H₂O)₆]­[UO₂(L)₃]₂ complexes depending on the carboxylate ion L (acetate, propionate, or <i>n</i>-butyrate) are investigated using the method of molecular Voronoi–Dirichlet polyhedra. Actinide contraction in the series of U­(VI)–Np­(VI)–Pu­(VI) in compounds <b>I</b>–<b>III</b> is reflected in a decrease in the mean AnO bond lengths and in the volume and sphericity degree of Voronoi–Dirichlet polyhedra of An atoms

Syntheses, Crystal Structures, and Nonlinear Optical Activity of Cs₂Ba[AnO₂(C₂H₅COO)₃]₄ (An = U, Np, Pu) and Unprecedented Octanuclear Complex Units in KR₂(H₂O)₈[UO₂(C₂H₅COO)₃]₅ (R = Sr, Ba)

X-ray diffraction was applied to the elucidation of crystal structures of single crystals of Cs₂Ba­[AnO₂(C₂H₅COO)₃]₄, where An = U­(<b>I</b>), Np­(<b>II</b>), Pu­(<b>III</b>), and KR₂(H₂O)₈[UO₂(C₂H₅COO)₃]₅, where R = Sr­(<b>IV</b>), Ba (polymorphs <b>V-a</b> and <b>V</b><b>-</b><b>b</b>). FTIR spectra were analyzed for the uranium-containing crystals <b>I</b>, <b>I</b><b>V</b>, and <b>V</b><b>-</b><b>b</b>. Isostructural cubic crystals <b>I</b>–<b>I</b><b>I</b><b>I</b> are constructed of typical mononuclear anionic complex units [AnO₂(C₂H₅COO)₃]⁻ and charge-balancing Cs and Ba cations. Features of actinide contraction in the six U–Np–Pu isostructural series known to date are analyzed. In crystal structures of <b>IV</b> and <b>V</b> two typical complexes [UO₂(C₂H₅COO)₃]⁻ bind with a hydrated Sr or Ba cation to form the rare trinuclear neutral complex unit {<i>R</i>(H₂O)₄[UO₂(C₂H₅COO)₃]₂}, where R = Sr, Ba. Two such trinuclear units and one typical mononuclear unit further bind with a K cation to form the unprecedented octanuclear neutral complex unit K­[UO₂(C₂H₅COO)₃]­{R­(H₂O)₄[UO₂(C₂H₅COO)₃]₂}₂. As the derived polynuclear complexes of uranyl ion with carboxylate ligands in the crystal structures of <b>IV</b> and <b>V</b> are not the first but are rare examples, the equilibrium between mono and polynuclear complex units in aqueous solutions is discussed. The two polymorphic modifications <b>V-a</b> and <b>V-b</b> were studied at 100 K and at room temperature, respectively. Peculiarities of noncovalent interactions in crystal structures of the two polymorphs are revealed using Voronoi–Dirichlet tessellation. The nonlinear optical activity of noncentrosymmetric crystals <b>I</b> was estimated by its ability for second harmonic generation