Vegetation succession on glacier forelands in the Jostedalsbreen region and Jotunheimen, south-central Norway

In this study four different aspects of primary successions on glacier forelands in South-Central Norway are investigated. First, general vegetation and environment trends, which have been observed by other scientists, were studied on two forelands. It is shown that the two selected forelands (one low- and one high-altitude foreland, Nigardsbreen and Storbreen, respectively) differ in the speed of vegetation cover change and in the overall species richness developed over the last 250 years since deglaciation. This is attributed to differences in the severity of the environment between the two forelands. Some support for an early peak in the number of species was found for the Nigardsbreen foreland, whereas the Storbreen foreland shows no significant trend in the development of species richness. Life-forms and soil-depth change on both forelands in the predicted manner. A novel approach for the use of Ellenberg indicator values for the estimation of pH-values from the existent vegetation shows highly significant correlations between predicted pH values and trends measured for similar terrain ages from a study by Messer (1988). Investigation at two different scales indicated that small-scale disturbances (< 100 m) may influence the mosaic of the environment, which affects the results of the chronosequence approach. By using a strict geometrical sampling design more variable conditions entered the analyses than with the stratified random sampling schemes adopted by others, such as Matthews (1979b). Some loss in the power of analysing the data occurred, but the results are still consistent with hypotheses about primary succession on glacier forelands. Second, new aspects of the temporal development and successional change of plant communities were investigated on the same two forelands. There is some evidence of succession from a pioneer community to the local climax community of the surrounding area for both forelands. There is also support for the correlation of timedependent environmental variables with the successional development of plant communities. A new application of Ellenberg indicator values in ordinations was assessed for its value in estimating average environmental conditions derived from the vegetation. As with the previous analyses, investigation of community development at two different scales supported the importance of sampling scale on the analysis of succession data. Third, spatially explicit analyses of distribution patterns of dominant woody species was developed as a means to investigate processes and formulate hypotheses about primary succession on glacier forelands. The data for this part of the study was collected on five glacier forelands, three low-altitude (Nigardsbreen, Austerdalsbreen and Bødalsbreen) and two high-altitude (Storbreen and Høgvaglbreen). Pattern descriptors including perimeter/area index, autocorrelation measures and fractal dimensions, support the hypothesis of differential colonisation of wind and animaldispersed species. Even more convincing is the result that low- and high-altitude forelands show significant differences in the patterns exhibited by wind and animals dispersed species. This result is thought to be related to the differences in environmental severity affecting the establishment of colonising species. Finally, logit modelling of the distributions of dominant woody species provides insights into the sampling effort needed to gather enough data for meaningful analyses. It also leads to the identification of important factors influencing the distribution of those species.</p

The distribution of phosphodiesterase 2A in the rat brain

The phosphodiesterases (PDEs) are a superfamily of enzymes that regulate spatio-temporal signaling by the intracellular second messengers cAMP and cGMP. PDE2A is expressed at high levels in the mammalian brain. To advance our understanding of the role of this enzyme in regulation of neuronal signaling, we here describe the distribution of PDE2A in the rat brain. PDE2A mRNA was prominently expressed in glutamatergic pyramidal cells in cortex, and in pyramidal and dentate granule cells in the hippocampus. Protein concentrated in the axons and nerve terminals of these neurons; staining was markedly weaker in the cell bodies and proximal dendrites. In addition, in both hippocampus and cortex, small populations of non-pyramidal cells, presumed to be interneurons, were strongly immunoreactive. PDE2A mRNA was expressed in medium spiny neurons in neostriatum. Little immunoreactivity was observed in cell bodies, whereas dense immunoreactivity was found in the axon tracts of these neurons and their terminal regions in globus pallidus and substantia nigra pars reticulata. Immunostaining was dense in the medial habenula, but weak in other diencephalic regions. In midbrain and hindbrain, immunostaining was restricted to discrete regions of the neuropil or clusters of cell bodies. These results suggest that PDE2A may modulate cortical, hippocampal and striatal networks at several levels. Preferential distribution of PDE2A into axons and terminals of the principal neurons suggests roles in regulation of axonal excitability or transmitter release. The enzyme is also in forebrain interneurons, and in mid- and hindbrain neurons that may modulate forebrain networks and circuits

The role of nurses in preventing adverse events related to respiratory dysfunction: literature review

Aims. This paper reports a literature review examining the relationship between specific clinical indicators of respiratory dysfunction and adverse events, and exploring the role of nurses in preventing adverse events related to respiratory dysfunction.Background. Adverse events in hospital are associated with poor patient outcomes such as increased mortality and permanent disability. Many of these adverse events are preventable and are preceded by a period during which the patient exhibits clearly abnormal physiological signs. The role of nurses in preserving physiological safety by early recognition and correction of physiological abnormality is a key factor in preventing adverse events.Methods. A search of the Medline and CINAHL databases was conducted using the following terms: predictors of poor outcome, adverse events, mortality, cardiac arrest, emergency, oxygen, supplemental oxygen, oxygen therapy, oxygen saturation, oxygen delivery, assessment, patient assessment, physical assessment, dyspnoea, hypoxia, hypoxaemia, respiratory assessment, respiratory dysfunction, shortness of breath and pulse oximetry. The papers reviewed were research papers that demonstrated a relationship between adverse events and various clinical indicators of respiratory dysfunction.Results. Respiratory dysfunction is a known clinical antecedent of adverse events such as cardiac arrest, need for medical emergency team activation and unplanned intensive care unit admission. The presence of respiratory dysfunction prior to an adverse event is associated with increased mortality. The specific clinical indicators involved are alterations in respiratory rate, and the presence of dyspnoea, hypoxaemia and acidosis.Conclusions. The way in which nurses assess, document and use clinical indicators of respiratory dysfunction is influential in identifying patients at risk of an adverse event and preventing adverse events related to respiratory dysfunction. If such adverse events are to be prevented, nurses must not only be able to recognise and interpret signs of respiratory dysfunction, but must also take responsibility for initiating and evaluating interventions aimed at correcting respiratory dysfunction.<br /