A Study on Impact of Clinical Pharmacist Interventions on Medication Adherence and Quality of Life in Rural Hypertensive Patients

Hypertension is the very common chronic disease in rural, urban and semi-urban areas of today's world, which needs continuous monitoring and treatment through out the life. Lack of education, lifestyle modification, and low level of understanding on disease management in rural people will influence directly on their quality of life (QOL). The objective of this study was to know the impact of clinical pharmacist interventions on medication adherence and QOL. It was a prospective, randomized and interventional study. Fifty-six patients were enrolled; only 52 patients completed the study. Interventional group patients received patient counselling, patient information leaflets (PILS), and frequent telephonic reminding. In the baseline, first and second follow-ups, medication adherence and QOL were assessed by using Morisky Medication Adherence Scale (MMAS) and Medication Adherence Report Scale (MARS) Questionnaires and SF-12v2 Quality of life Questionnaire in both the groups. The results showed that systolic blood pressure P value in the second follow-up was 0.086+ when compared to baseline follow-up P value 0.094. The diastolic blood pressure reading of the intervention group at the second follow-up was 77.73 ± 3.63 in mmHg when compared to the baseline, i.e. 86.62 ± 11.35 in mmHg. The MMAS and MARS scores P values were 0.007**, 1.000, <0.001**; 0.007, 0.014 and 0.000 at the baseline, first and second follow-ups, respectively. The QOL score P values of physical component scale and mental component scale showed highly significant. This study concluded/showed that the impact of clinical pharmacist provided patient counselling had a positive impact on medication adherence and QOL

The B^- -> phi phi K^- decay rate with phi phi invariant mass below charm treshold

We investigate the decay mechanism in the B^- -> phi phi K^- decay with the phi phi invariant mass below the charm threshold and in the neighborhood of the eta_c invariant mass region. Our approach is based on the use of factorization model and the knowledge of matrix elements of the weak currents. For the B meson weak transition we apply form factor formalism, while for the light mesons we use effective weak and strong Lagrangians. We find that the dominant contributions to the branching ratio come from the eta, eta' and eta(1490) pole terms of the penguin operators in the decay chains B^- -> eta (eta', eta(1490)) K^- -> phi phi K^-. Our prediction for the branching ratio is in agreement with the Belle's result.Comment: 14 pages, 4 figures, 2 table