Evaluation of Postural Stability with a Biodex Balance System After Cranial MRI Examination

Aim:The aim of this study was assess the postural stability of patients exposed to strong magnetic fields during magnetic resonance imaging (MRI) quantitatively with biodex stability system (BSS).Materials and Methods:Patients included in the study were selected among the patients who applied to the radiology clinic for brain MRI. Patients with any orthopedic, neurological, visual, auditory and systemic diseases that may cause postural stability disorder were excluded from the study. Postural stability was evaluated by BSS, which can be used for both static and dynamic evaluation and also provides quantitative measurement. Evaluation was performed before and immediately after MRI. Mediodateral, anteroposterior, general stability indices and fall risk index values were measured with BSS. It was evaluated whether there was a statistically significant difference between the values obtained before and after MRI.Results:Forty patients were included in the study. Of these patients, 18 were male and 22 were female. The mean age was 41.3 ± 17.3 years. When postural stability measurement values were compared before and after MRI, a significant increase was found in mediolateral stability and fall risk index values (p = 0,03, p = 0,01, respectively). There was no significant difference between general stability and anteroposterior stability index values (p> 0.05).Conclusion:Mediolateral stability and fall risk index parameters increase in quantitative evaluation of postural stability in patients exposed to high magnetic field by cranial MRI. We think it is helpful to warn especially high-risk patients that postural stability may deteriorate after cranial MRI

Dermatolojik Hastalıklarda Demodex spp. Prevalansının Araştırılması

Amaç: Sağlıklı bireylerin mikrobiyotasında bulunan Demodex akarlarının sayısal artışına bağlı olarak bazı dermatolojik hastalıkların ortaya çıktığı düşünülmektedir. Bu çalışmada, akne vulgaris, rosacea, perioral dermatit, seboreik dermatit, egzama ve pityriasis folliculorum tanılı hastalarda Demodex spp. prevalansının ve bu hastalara ait demografik ve klinik verilerin Demodex ile ilişkisinin araştırılması amaçlanmıştır. Yöntemler: Çalışmaya 144 hasta (70 akne vulgaris, 6 pityriasis folliculorum, 15 seboreik dermatit, 39 rosacea, 8 egzema ve 6 perioral dermatit) ve 73 sağlıklı gönüllü dahil edilmiştir. Demodex pozitifliği, tüm gruplarda standart yüzeyel deri biyopsi yöntemi ile değerlendirilmiştir. Tanıda cm2’de beşten fazla Demodex akarı görülmesi pozitif kabul edilmiştir. Bulgular: Çalışmaya alınan 144 hastanın 107’si (%74,3) kadın, 37’si (%25,7) erkek, 73 sağlıklı gönüllünün 40’ı (%54,8) kadın, 33’ü (%45,2) erkektir. Yüz kırk dört hastanın 21’inde (%14,5), 73 sağlıklı gönüllünün ise 5’inde (%6,8) Demodex pozitifliği saptanmıştır. Rosecea ve akne vulgaris gruplarındaki Demodex pozitiflik oranlarının kontrol grubuna göre yüksek olduğu, ancak bu yüksekliğin istatistiksel olarak anlamlı olmadığı tespit edilmiştir (p>0,05). Hasta grupları içerisinde en yüksek pozitiflik oranının sırasıyla pityriasis folliculorum (4/6, %66,7), rosacea (8/39, %20,5) ve perioral dermatit (1/6, %16,7) gruplarında olduğu saptanmıştır. Grupların demografik ve klinik özellikleri ile Demodex pozitifliği arasında istatistiksel olarak anlamlı bir ilişki bulunamamıştır (p>0,05). Sonuç: Bu çalışma, altı farklı dermatolojik hastalığın varlığında Demodex pozitifliğini araştıran literatürdeki tek çalışmadır. Çalışma sonuçlarına göre; rosacea, akne vulgaris ve pityriasis folliculorum gibi dermatolojik hastalıklarda Demodex spp. pozitifliğinin araştırılmasının erken tanı ve tedavi açısından yararlı olacağı düşünülmektedir

Retrospective Analysis of Patients with Basal Cell Carcinoma Diagnosed in Our Clinic

Aim:Basal cell carcinoma (BCC) is the most common malignancy of the skin and its incidence is steadily increasing. The aim of our study was to reveal the clinical and demographic characteristics of BCC.Materials and Methods:The study included 273 BCC that were histopathologically diagnosed in 256 patients who admitted the Dermatology Clinic of Tekirdağ Namık Kemal University between January 2014 and January 2019. The patients’ age, gender, tumor histological subtype, tumor localization, and co-morbid conditions were all assessed retrospectively in the study.Results:The mean age of the 256 patients included in the study with BCC was statistically 67.67, with the youngest patient being 32 and the oldest patient being 104 years old. Of the patients, 137 were male (56.5%), and 119 were female (46.5%). The most common histopathological subtype observed was the nodular type, accounting for 61.5% (n=168), and the most frequent localization was the head and neck region, accounting for 88.3% (n=241).Conclusion:BCC is the most common epidermal malignancy of the skin, characterized by a slow growth pattern and a locally invasive nature. It often occurs in individuals aged 50 and above, particularly in the head and neck region where there is intense exposure to ultraviolet radiation. In our study, we also observed that BCC was most frequently seen in the 70-80 age range, primarily in the head and neck region, and predominantly in the nodular subtype. The superficial type was more commonly observed on the trunk. Although the incidence of BCC is similar between males and females, it tends to occur more frequently in females at younger ages

Lichen nitidus presenting with trachyonychia

[No Abstract Available

One Side Two Extremity Places Inflammatory Linear Verrucous Epidermal Nevus

İnflamatuar lineer epidermal verrüköz nevüs (İLVEN), nadir görülen ve daha çok doğumda ve adölesan dönemde ortaya çıkan kaşıntılı, lineer yerleşimli, eritemli, verrüköz papüllerden oluşan bir hastalıktır. İLVEN, verrüköz epidermal nevüsün ender bir varyantı olup, kronik egzamatöz veya psoriasiform yönü ile tekrarlayan inflamatuvar olaylarla karakterizedir. Erişkin dönemde ortaya çıkması oldukça nadir görülür. Klinik ve histolojik muayene ile tanı konulur. Diğer epidermal nevüsler, lineer psoriasis ve liken striatus gibi çeşitli dermatozlarla ayırıcı tanısı yapılmalıdır. Tedaviye belirgin derecede dirençli bir hastalıktır. Biz de bu olgumuzda el ve ayak tutulumu olan doğumsal başlangıçlı 22 yaşındaki hastayı rutinde az rastlanan bir hastalık olduğu için sunmayı uygun buldukInflamatory linear verrucous epidermal nevus (ILVEN), present as itchy, linear, erythematous, verrucous papules that develop at birth or during adolescence. ILVEN is a rare variant of verrucous epidermal nevus characterized by recurrent inflammatory events with chronic eczematous or psoriasiform aspect. It is very rare during adulthood. Diagnose made by clinical and histological examination. Differential diagnosis should be made with various dermatoses such as other epidermal nevi, linear psoriasis and lichen striatus. It is resistant to treatment. We found it appropriate to present a congenital onset of a 22 year old patient as a rare disease in routine

One Side Two Extremity Places Inflammatory Linear Verrucous Epidermal Nevus

Inflamatory linear verrucous epidermal nevus (ILVEN), present as itchy, linear, erythematous, verrucous papules that develop at birth or during adolescence. ILVEN is a rare variant of verrucous epidermal nevus characterized by recurrent inflammatory events with chronic eczematous or psoriasiform aspect. It is very rare during adulthood. Diagnose made by clinical and histological examination. Differential diagnosis should be made with various dermatoses such as other epidermal nevi, linear psoriasis and lichen striatus. It is resistant to treatment. We found it appropriate to present a congenital onset of a 22 year old patient as a rare disease in routine

Relationship between vitamin D in obstructive sleep apnea syndrome and psoriasis patients

Introduction: Although psoriasis and obstructive sleep apnea syndrome (OSAS) are associated with systemic inflammation, studies on their potential bilateral relationship are not sufficient. Aim: To investigate vitamin D levels and receptor gene polymorphisms in patients with OSAS and psoriasis and the associations with these diseases. Material and methods: One hundred thirty-seven patients included in the study consisted of 4 different groups: group 1, those with both diseases; group 2, those with OSAS only; group 3, patients with psoriasis only; and group 4, healthy controls. The patients??? serum calcium, phosphorus, AHI, Epworth Sleepiness Scale, Psoriasis Area Severity Index, and VDR TagI, ApaI, BsmI polymorphisms were compared. Results: Vitamin D levels of groups 1, 2 and 3 were found to be lower than in controls. There was no statistically significant correlation between VDR TagI, ApaI, BsmI gene polymorphisms of the groups. Vitamin D levels were significantly higher in patients with heterozygous ApaI genotype (A/C) compared to patients with normal (A/A) or homozygous mutant (C/C) genotype (p < 0.05). No relationship was determined between VDR TagI, ApaI, BsmI, and the other parameters. Conclusions: In our study, 1,25(OH)2-vitamin D3 levels were significantly lower in all disease groups compared to the control group. Although there is no difference between the groups in terms of VDR gene polymorphism, we think that there may be a bidirectional relationship between these diseases based on the low vitamin D levels.Namik Kemal University Scientific Research Projects Coordination Unit [NKUBAP.02, 18.188]A this study was supported by Namik Kemal University Scientific Research Projects Coordination Unit (Project Number NKUBAP.02.GA.18.188)

Cutaneous reactions after COVID-19 vaccination in Turkey: A multicenter study

Objectives In this study covering all of Turkey, we aimed to define cutaneous and systemic adverse reactions in our patient population after COVID-19 vaccination with the Sinovac/CoronaVac (inactivated SARS-CoV-2) and Pfizer/BioNTech (BNT162b2) vaccines. Methods This prospective, cross-sectional study included individuals presenting to the dermatology or emergency outpatient clinics of a total of 19 centers after having been vaccinated with the COVID-19 vaccines. Systemic, local injection site, and non-local cutaneous reactions after vaccination were identified, and their rates were determined. Results Of the 2290 individuals vaccinated between April 15 and July 15, 2021, 2097 (91.6%) received the CoronaVac vaccine and 183 (8%) BioNTech. Systemic reactions were observed at a rate of 31.0% after the first CoronaVac dose, 31.1% after the second CoronaVac dose, 46.4% after the first BioNTech dose, and 46.2% after the second BioNTech dose. Local injection site reactions were detected at a rate of 35.6% after the first CoronaVac dose, 35.7% after the second CoronaVac dose, 86.9% after the first BioNTech dose, and 94.1% after the second BioNTech dose. A total of 133 non-local cutaneous reactions were identified after the CoronaVac vaccine (2.9% after the first dose and 3.5% after the second dose), with the most common being urticaria/angioedema, pityriasis rosea, herpes zoster, and maculopapular rash. After BioNTech, 39 non-local cutaneous reactions were observed to have developed (24.8% after the first dose and 5% after the second dose), and the most common were herpes zoster, delayed large local reaction, pityriasis rosea, and urticaria/angioedema in order of frequency. Existing autoimmune diseases were triggered in 2.1% of the patients vaccinated with CoronaVac and 8.2% of those vaccinated with BioNTech. Conclusions There are no comprehensive data on cutaneous adverse reactions specific to the CoronaVac vaccine. We determined the frequency of adverse reactions from the dermatologist's point of view after CoronaVac and BioNTech vaccination and identified a wide spectrum of non-local cutaneous reactions. Our data show that CoronaVac is associated with less harmful reactions while BioNTech may result in more serious reactions, such as herpes zoster, anaphylaxis, and triggering of autoimmunity. However, most of these reactions were self-limiting or required little therapeutic intervention

Role of GDF-15 as an inflammatory marker in patients with psoriasis vulgaris

Background and Design: Psoriasis is a chronic, inflammatory disease, and several biochemical markers play role in its inflammatory process. This study measured the levels of interleukin-12 (IL-12), IL-17a, IL-22 and IL-23, high-sensitivity C-reactive protein (hs-CRP), tumor necrosis factor-alpha (TNF-alpha) and serum growth differentiation factor-15 (GDF-15) and aimed to detect the relationship of serum GDF-15 level with inflammation and disease severity. Materials and Methods: This study included 50 consecutive patients diagnosed with plaque-type psoriasis. For all patients, dermatological examinations were performed, and psoriasis area severity index (PASI) scores were recorded. Patients with PASI 20 severe (group 3) psoriasis. Results: No difference was observed between the patient and the control groups in terms of age, sex, IL-17a and IL-22. A statistically nonsignificant difference was detected in terms of IL-12 and IL-23. However, there was significant difference between two groups in terms of hs-CRP, TNF-alpha and GDF-15. GDF-15 was significantly different in all three groups (p1498.5 pg/mL (area under the curve: 0.813, p<0.001) in the receiver operating characteristic curve analysis. This study is mainly limited by the lack of follow-up and pre-and post-treatment assessment. Inflammatory markers were measured only in the serum, and their tissue levels are unknown. Conclusion: In addition to PASI score, GDF-15 levels can be a guide in monitoring treatment and systemic inflammation, determining the disease severity, and providing efficient treatment

Clinical, Demographic and Laboratory Results of Dermatomycosis Patients in Tekirdag Region

Aim:Dermatomycosis factors can change over time with geographical region, climate, socioeconomic status and lifestyle. In this study, we retrospectively evaluated the patients who admitted our dermatology clinic with the preliminary diagnosis of dermatomycosis. Demographic data of the patients who admitted to our hospital and the factors isolated from the samples investigated.Materials and Methods:This study performed in January 2017 to December 2017 at Dermatology Department of Namık Kemal University School of Medicine. A total 448 samples obtained from patients who referred to the Dermatology clinic with a preliminary diagnosis of dermatomycosis were retrospectively evaluated.Results:In our study, the most frequent admissions to hospital were due to toe nail changes (28.5%), followed by trunk lesions (24.3%) and foot lesions except nail (22.5%).The most common differential diagnosis was lesions on the trunk (44.4%) followed by foot skin lesions (22.2%). Direct microscopic examination was positive in 35,8% specimens while fungal culture was positive in 5,8% cases. Trichophyton rubrum (56%) was the most common pathogen, followed by Candida albicans (12%) and Microsporum canis (8%).Conclusion:Foot lesions were the most common reason for admission to the hospital and Trichophyton rubrum was the most common causative agent. We think that increasing number of immunosuppressive individuals in the community revealed Candida albicans as the second agent. The high number of patients with onychomycosis and tinea pedis suggests that foot hygiene, care and protection is a social problem