Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362

Allometric biomass estimators for aspen dominated ecosystems in the Upper Great Lakes

Presents allometric estimators relating aboveground and belowground component weights to diameter measurements of more than 2,500 trees and shrubs encompassing 35 woody species samples from 8 soil series. The estimators were only weakly related to soil character but were strongly influenced by population density variation induced by silvicultural treatment

Acidification of soils by trees and forests.

The impact of isolated trees and natural forest vegetation on soil acidity is discussed. There is a considerable variation in impact between species on similar soils and between sites for any given species. The effect of coniferous plantations on soil acidity is reviewed and the causes of any increased acidity discussed. Crop species, initial soil conditions, silvicultural practices and the proportion of the tree removed at felling are all important factors influencing the long-term impact of plantations on soil acidity

Forests planted for ecosystem restoration or conservation

Abstract. Although the phrase, &quot;&apos;planting for ecosystem restoration, &quot; is of recent origin, many of the earliest large-scale tree plantings were made for what we now refer to as &quot;&apos;restoration&quot; or &quot;conservation &quot; goals. Forest restoration activities may be needed when ecosystems are disturbed by either natural or anthropogenic forces. Disturbances can impact (1) basic components of the system (e.g., plant and animal composition, soil pools, and atmospheric pools), (2) ecosystem processes, i.e., interactions among basic components, or (3) both components and processes. Early efforts at restoration or site rehabilitation focused primarily on reducing off-site impacts, such as sediment introduced into streams from ecosystems that had been severely disturbed. More recent restoration programs include ecosystems in which only some of the components are missing or some of the processes have been impacted. Restoration activities can begin immediately after the disturbance has ended. Although forest restoration projects can include many activities, planting is almost always a key component. When planning an ecosystem restoration project, land managers need to be aware that commonly used plant establishment and management procedures may need to be altered to meet project objectives. Some systems may have been so severely impacted that ameliorativ