Volumetric study of the olfactory bulb in patients with chronic rhinonasal sinusitis using MRI

AbstractObjectiveOlfaction plays an important role in human daily life. The olfactory bulb size is dependent on stimulation. Smell loss is one of the main symptoms in chronic rhinonasal sinusitis. MRI has been indicated to evaluate the size of the olfactory bulb in such patients.The aim of this study was to assess the volumetric changes of the olfactory bulb in patients with sinonasal polyposis before and after treatment using MRI.Patients and methodsFifteen control subjects and 30 patients were included in the study, 24 of them patients underwent endoscopic sinus surgery. Volumetric analysis of their olfactory bulb volume was done using MRI and specialized software.ResultsIt was found that the olfactory bulb volume was significantly smaller in patients (19.98±5.88mm3) when compared to control mean (39.6±13.8mm3) and there was a significant increase in the olfactory bulb volumes in patients who underwent surgery 6months postoperatively (24.79±5.11mm3).ConclusionsMRI with volumetric analysis is a useful tool in assessment of the olfactory bulb volume in patients with olfactory loss and appears to be of help in assessment of the degree of recovery in patients after sinus surgery

Evaluation of coronary stents using mult

Background: Recurrent ischemic symptoms after coronary stenting require imaging assessment to rule-out in-stent restenosis or occlusion. Aim: To evaluate role of multi-detector computed tomography in assessment of coronary artery stents. Patients and methods: Twenty-four patients were referred to assess coronary stents. All were subjected to history taking, clinical examination and computed tomography angiography of coronary arteries using 320-row multi-detector computed tomography. Results: There were totally sixty-three coronary artery stents. Only six stents were non-interpretable. Where forty-eight patent, while nine stents showed in-stent restenosis of significant degree (⩾50%), most stents 3.0 mm diameter. Conclusion: Multi-detector computed tomography is considered convenient and reliably non-invasive imaging modality for assessment of suspected coronary stents with large diameter

Functional disability of occupational-related lumbar disc degeneration: Evaluation by magnetic resonance imaging with surgical correlation

Objectives: The objectives of our work were to determine disability and study MRI findings of occupational-related lumbar disc degeneration and also to show the relationship between MRI grading of nerve root compromise with surgical grading. Participants and methods: The study included 103 workers with lumbar disc prolapse. Nerve roots were assessed on MRI and during surgery for the degree of compromise. Oswestry Disability Index and Visual Analogue Scale were used for assessment of disability and pain intensity pre- and post-operative respectively. Results: The majority of workers was less than 40 years and suffered from moderate to severe disability. 73.8% had grade IV disc degeneration mostly at the level of L4/L5. Nerve root compromise was found in 86.4% of workers. 48% of nerve roots were deviated and 32% were compressed, with significant correlation between MR grading of nerve root compromise and surgical grading (r = 0.89, P < 0.0001). Conclusion: Disability of occupational-related lumbar disc degeneration is a grave health problem between construction workers. MR imaging is a reliable tool for grading nerve root compromise in disc degeneration. Nerve root compromise is a significant factor to explain pain than the morphologic extension of disc material outside the intervertebral space

Brain volumetrics, regional cortical thickness and radiographic findings in children with cyanotic congenital heart disease using quantitative magnetic resonance imaging

Background: Hypoxia in children with cyanotic congenital heart disease may cause structural brain changes. Objectives: 1. To assess brain volumetrics and ischemic brain lesions in children with cyanotic congenital heart disease using quantitative MRI. 2. To study the correlation between MRI findings, oxygen saturations and some laboratory measures. Participants and methods: Fifty children with CCHD and a mean oxygen saturation of 83 ± 2.2% were investigated using quantitative MRI. Brain volumetric results were compared with 20 controls. Results: Dilated Ventricles were found in 14 cases (28%). 23 cases (46%) had PWM hyper-intensity. The common sites for DWML were sub-cortical that was detected in 17 cases (34%). Sub-cortical lacunar infarcts in GM were found in 8 cases (16%). Significant WM and GM volume loss was found in cyanosed subjects. The volumes of the thalamus (P = 0.01), putamen (P = 0.003), and caudate (P = 0.042) were significantly reduced in the cyanotic group. Local regions of decreased cortical thickness were detected in frontal, parietal and temporal lobes. Conclusions: Children with CCHD show MRI evidence of micro- and macro vascular injury, reduced brain volume and cortical thickness. Brain volume loss correlated with hsCRP, oxygen saturation and packed cell volume