First recorded occurrence of Cheirocratus robustus Sars, 1894 in the British Isles

Background: Collections of the amphipod genus Cheirocratus from the North Sea and Ireland proved to include C. robustus Sars a species previously known only from Norway and Sweden. Results: Material of C.robustus is described and figured from the Humber and Ireland together with the closely related species C. sundevalli (Rathke). A key to males of the Cheirocratus species of the North East Atlantic and Mediterranean is provided. Conclusions: C. robustus is shown to be widespread in the eastern North Atlantic where it was previously overlooked

Amphipod Crustacea I. Family Aoridae

(75pp.

Integrated functions among multiple starch synthases determine both amylopectin chain length and branch linkage location in Arabidopsis leaf starch

This study assessed the impact on starch metabolism in Arabidopsis leaves of simultaneously eliminating multiple soluble starch synthases (SS) from among SS1, SS2, and SS3. Double mutant ss1- ss2- or ss1- ss3- lines were generated using confirmed null mutations. These were compared to the wild type, each single mutant, and ss1- ss2- ss3- triple mutant lines grown in standardized environments. Double mutant plants developed similarly to the wild type, although they accumulated less leaf starch in both short-day and long-day diurnal cycles. Despite the reduced levels in the double mutants, lines containing only SS2 and SS4, or SS3 and SS4, are able to produce substantial amounts of starch granules. In both double mutants the residual starch was structurally modified including higher ratios of amylose:amylopectin, altered glucan chain length distribution within amylopectin, abnormal granule morphology, and altered placement of α(1→6) branch linkages relative to the reducing end of each linear chain. The data demonstrate that SS activity affects not only chain elongation but also the net result of branch placement accomplished by the balanced activities of starch branching enzymes and starch debranching enzymes. SS3 was shown partially to overlap in function with SS1 for the generation of short glucan chains within amylopectin. Compensatory functions that, in some instances, allow continued residual starch production in the absence of specific SS classes were identified, probaby accomplished by the granule bound starch synthase GBSS1.ANR Génoplante GPLA0611GEuropean Union-FEDER, Région Nord Pas de Calais ARCir PlantTEQ5National Science Foundation DBI-0209789Comisión Interministerial de Ciencia y Tecnología BIO2009-07040Junta de Andalucía P09-CVI-470

A Kiloparsec-Scale Binary Active Galactic Nucleus Confirmed by the Expanded Very Large Array

We report the confirmation of a kpc-scale binary active galactic nucleus (AGN) with high-resolution radio images from the Expanded Very Large Array (EVLA). SDSS J150243.1+111557 is a double-peaked [O III] AGN at z = 0.39 selected from the Sloan Digital Sky Survey. Our previous near-infrared adaptive optics imaging reveals two nuclei separated by 1.4" (7.4 kpc), and our optical integral-field spectroscopy suggests that they are a type-1--type-2 AGN pair. However, these data alone cannot rule out the single AGN scenario where the narrow emission-line region associated with the secondary is photoionized by the broad-line AGN in the primary. Our new EVLA images at 1.4, 5.0, and 8.5 GHz show two steep-spectrum compact radio sources spatially coincident with the optical nuclei. The radio power of the type-2 AGN is an order-of-magnitude in excess of star-forming galaxies with similar extinction-corrected [O II] 3727 luminosities, indicating that the radio emission is powered by accretion. Therefore, SDSS J150243.1+111557 is one of the few confirmed kpc-scale binary AGN systems. Spectral-energy-distribution modeling shows that SDSS J150243.1+111557 is a merger of two ~10^{11} M_sun galaxies. With both black hole masses around 10^8 Msun, the AGNs are accreting at ~10 times below the Eddington limit.Comment: ApJL accepted. 6 pages, 3 figures, 1 tabl

Measuring participation in an evidence-based practice: Illness management and recovery group attendance

Given the important role of treatment attendance as an indicator of program implementation and as a potential moderator of program effectiveness, this study sought to develop useful indicators of attendance for evidence-based practices. The current study examined consumer attendance patterns in a randomized controlled trial comparing illness management and recovery (n = 60) to a problem solving control condition (n = 58). Associations were examined between consumer clinical indicators, demographics, and level of recovery and indices of attendance. Attendance was poor, but comparable to rates found in many other studies. Four indicators of attendance (percent sessions attended, time enrolled, periods of attendance, and longest period of attendance) were highly inter-related and were more sensitive to baseline differences than a traditional approach of dichotomizing participants into “attenders” and “non-attenders.” Older age, lower hostility, fewer psychotic symptoms, and more education were associated with higher group attendance in both treatment conditions; the client-reported illness management and recovery scale was associated with attendance in the control group. Indicators of attendance were an advancement over dichotomous classification. Strategies to increase attendance are still needed, particularly for younger consumers with greater positive symptoms

Mean Field Theory of Collective Transport with Phase Slips

The driven transport of plastic systems in various disordered backgrounds is studied within mean field theory. Plasticity is modeled using non-convex interparticle potentials that allow for phase slips. This theory most naturally describes sliding charge density waves; other applications include flow of colloidal particles or driven magnetic flux vortices in disordered backgrounds. The phase diagrams exhibit generic phases and phase boundaries, though the shapes of the phase boundaries depend on the shape of the disorder potential. The phases are distinguished by their velocity and coherence: the moving phase generically has finite coherence, while pinned states can be coherent or incoherent. The coherent and incoherent static phases can coexist in parameter space, in contrast with previous results for exactly sinusoidal pinning potentials. Transitions between the moving and static states can also be hysteretic. The depinning transition from the static to sliding states can be determined analytically, while the repinning transition from the moving to the pinned phases is computed by direct simulation.Comment: 30 pages, 29 figure

Improving reference equations for cardiorespiratory fitness using multiplicative allometric rather than additive linear models: Data from the Fitness Registry and the Importance of Exercise National Database Registry

New improved reference equations for cardiorespiratory fitness have recently been published, using Data from the Fitness Registry and the Importance of Exercise National Database (FRIEND Registry). The new linear equation for VO2max (ml.kg−1.min−1) was additive, derived using multiple-linear regression. An alternative multiplicative allometric model has also been published recently, thought to improve further the quality of fit. The purpose of the current study was to compare the accuracy and quality/goodness-of-fit of the linear, additive model with the multiplicative allometric model using the FRIEND database. The results identified that the allometric model out performs the linear model based on all model-comparison criteria. The allometric model demonstrates; 1) greater explained variance (R2 = 0.645; R = 0.803) vs. (R2 = 0.62; R = 0.79), 2) residuals that were more normally distributed, 3) residuals that yielded less evidence of curvature, 4) superior goodness-of-fit statistics i.e., greater maximum log-likelihood (MLL) and smaller Akaike Information Criterion (AIC) statistics, 5) less systematic bias together with smaller unexplained standard error of estimates. The Bland and Altman plots also confirmed little or no evidence of curvature with the allometric model, but systematic curvature (lack-of-fit) in the linear model. The multiplicative allometric model to predict VO2max was; VO2max (ml.kg−1.min−1) = M-0.854 · H1.44 · exp. (0.424–0.346 · (sex) -0.011.age), where M = body mass and H = height (R2 = 0.645; R = 0.803) and sex is entered as a [0,1] indicator variable (male = 0 and female = 1). Another new insight obtained from the allometric model (providing construct validity) is that the height-to-body-mass ratio is similar to inverse body mass index or the lean body mass index, both associated with leanness when predicting VO2max. In conclusion adopting allometric models will provide more accurate predictions of VO2max (ml.kg−1.min−1) using more plausible, biologically sound and interpretable models.Published versio

Hypertension treatment intensification among stroke survivors with uncontrolled blood pressure

Objective The study objective was to evaluate a pharmacist hypertension care management program within the patient-centered medical home. Methods This was a retrospective case-control study. Cases included all patients with hypertension who were referred to the care management program, and controls included patients with hypertension who were not referred to the program during the same 1-year period. Each case was matched to a maximum of 3 controls on the basis of primary care physician, age ±5 years, gender, diagnoses of diabetes and kidney disease, baseline systolic blood pressure ±10 mm Hg, and number of unique antihypertensive medications. Pharmacists provided a hypertension care management program under an approved scope of practice that allowed pharmacists to meet individually with patients, adjust medications, and provide patient education. Primary outcomes were systolic blood pressure and diastolic blood pressure at 6 and 12 months. Multivariate regression models compared each blood pressure end point between cases and controls adjusting for age, comorbidities, baseline blood pressure, and baseline number of blood pressure medications. Results A total of 573 patients were referred to the hypertension program; 86% (465/543) had at least 1 matched control and were included as cases in the analyses; 3:1 matching was achieved in 90% (418/465) of cases. At baseline, cases and controls did not differ with respect to age, gender, race, or comorbidity; baseline blood pressure was higher (139.9/80.0 mm Hg vs 136.7/78.2 mm Hg, P ≤ .0002) in the cases compared with controls. Multivariate regression modeling identified significantly lower systolic blood pressure for the cases compared with controls at both 6 and 12 months (6-month risk ratio [RR], 9.7; 95% confidence interval [CI], 2.7-35.3; 12-month RR, 20.3; 95% CI, 4.1-99.2; P < .01 for both comparisons). Diastolic blood pressure was significantly lower at 12 months (RR, 2.9; 95% CI, 1.2-7.1; P < .01) but not at 6 months (RR, 1.0; 95% CI, 0.31-3.4; P = .9) for the cases compared with controls. Conclusions Patients who were referred to the pharmacist hypertension care management program had a significant improvement in most blood pressure outcomes. This program may be an effective method of improving blood pressure control among patients in a medical home model of primary care