Effect of Dental Amalgam Silver Filling on Salivary Amylase Enzyme

The largest source of mercury located in dental amalgam fillings people. In this study, mercury level in saliva of amalgam and non-amalgam human were compared as well as the level of α amylase has been detected. Materialsand methods: The concentration of mercury, silver, and activity of amylase in saliva were measured in 55 adult study subjects. The mercury contents were determined by cold–vapor atomic absorption spectrometry. Results: The concentration of mercury in the serum was significantly higher in subjects with dental amalgam fillings (n = 25) compared to the non-amalgam group (n = 30) (p<0.01). The activity of α-amylase has significantly decreased in amalgam group. Conclusion: Higher amount of amalgam fillings synchronized with a lower activity of a- amylase.      Keywords:-Mercury, silver , α-amylas