LAYANAN PUBLIK BERBASIS ELEKTRONIK DI LAPAS SEBAGAI WUJUD ANTI KORUPSI

Penelitian ini bertujuan untuk mengetahui fenomena budaya korupsi di pemasyarakatan serta mengetahui upaya yang sudah dilakukan untuk membangun budaya anti korupsi. Permasalahan korupsi merupakan hal krusial yang dapat merusak suatu kehidupan berbangsa dan bernegara. Penelitian ini menggunakan pendekatan Kualitatif, dimana penelitian ini dilakukan dengan mencari informasi secara mendalam. Data yang dikumpulkan menggunakan metode Wawancara dan Observasi. Data yang sudah terkumpul kemudian diolah dan dianalisis setelah itu disimpulkan hasilnya. Pelayan publik berbasis elektronik di Lapas sebagai budaya anti korupsi merupakan langkah yang signifikan dilakukan oleh Lapas dalam memberantas korupsi. Untuk membersihkan sungai yang kotor atau tercemar bukan dari hulu sungai tetapi dari hilir sungai. Untuk memberantas korupsi memang penting membangun manusia yang sadar anti korupsi dengan budaya anti korupsi namun membangun sistem pelayanan publik dengan eletronik lebih signifikan atau membawa kemajuan dalam membangun budaya korupsi

Effects of maternal hypothyroxinemia on the expression of biochemical functions in the CNS of the adult rat

The importance of thyroid hormones in the development and maintenance of normal CNS functions, has long been well established. Iodine-deficient areas are scattered all over the world. Maternal hypothyroxinemia in early pregnancy, as a consequence of iodine deficiency, is associated with an increased incidence of neurological cretinism in the offspring. This condition is irreversible and is manifested in severe cases by mental retardation, deaf-mutism, diplegia of the inferior extremities, gait disorders and sometimes strabismus and stunted growth. In the adult, these conditions cannot be corrected by a normal thyroid state or replacement therapy, suggesting the existence of specific phases in early brain development during which correct exposure to thyroid hormones is of critical importance, and there is a possible fetal dependance on maternal thyroxine. However, the putative biochemical disorders associated with latter have not been studied in detail. The aim of the study was thus to evaluate the biochemical changes in different brain regions due to maternal hypothyroxinemia in an animal model. Seven month old (adult) progeny born to normal and partially thyroidectomised rat dams were used. Total protein, protein profiles of cytosolic and particulate fractions, neuronal cell marker enzymes, myelin metabolic enzymes (oligodendroglial cell markers), and certain lipids were studied. Body weight, brain weight and protein concentrations of brain regions in experimental progeny were apparently unchanged. On the other hand protein profiles of both cytosolic and particulate fractions demonstrated significant alterations in some brain regions. Cytosolic protein bands of 25 kD and 38 kD were significantly changed in medulla, while a 31 kD protein band was absent in this brain region. A 97 kD and a 89 kD cytosolic protein bands were also changed respectively in cerebral cortex and paleocortex of TX dam progeny. A 79 kD protein band was the only particulate protein which significantly increased in medulla in the experimental progeny. Significant changes were observed in myelin metabolic enzymes in specific brain regions of experimental progeny, e.g. CNPase activity was decreased in medulla by 37% (p<0.05) and in midbrain by 32% (p<0.05), and 5'-nucleotidase activity was decreased significantly in the same regions by 33% (p<0.05) and 35% (p<0.05), respectively. In paleocortex, oleate esterase activity (a myelin metabolic enzyme) was significantly increased by 39% (p<0.05), whereas β-D glucuronidase activity (a neuronal marker) was significantly decreased by 30% (p<0.05), N-acetyl-β-D galactosaminidase activity (a general glial marker) was unchanged and the activity of sphingomyelinase was also unchanged in all brain regions studied. No change was observed in the concentration of cholesterol (a major component of the myelin lipid) in any brain region but other two specific myelin lipids, cerebroside and sulphatide demonstrated significant changes in experimental progeny. The former was decreased in medulla and the latter also decreased in the midbrain and paleocortex of progeny. Changes in myelin metabolic enzymes and lipids have suggested a deficit in myelin metabolism of adult progeny from partially thyroidectomised dam. In conclusion, these findings indicate that the effects of maternal hypothyroxinemia are brain region-specific. These effects are also irreversible, since they are observed in adult progeny and persist despite a normal thyroid state. It is well known that glial cell proliferation and acquisition in the rat occurs postnatally, when the thyroid is functionally active. It is argued that the thyroid hormone environment of the fetus, before the onset of an independent fetal hypothalamic-pituitary-thyroid axis may be of critical importance for the expression of glial functions after birth. It is suggested that maternal hypothyroxinemia in early pregnancy may cause irreversible brain region- specific biochemical changes in adult progeny and thyroid hormones in early pregnancy may have an epigenic effect on the function of the adult CNS

On receiver design for low density signature OFDM (LDS-OFDM)

Low density signature orthogonal frequency division multiplexing (LDS-OFDM) is an uplink multi-carrier multiple access scheme that uses low density signatures (LDS) for spreading the symbols in the frequency domain. In this paper, we introduce an effective receiver for the LDS-OFDM scheme. We propose a framework to analyze and design this iterative receiver using extrinsic information transfer (EXIT) charts. Furthermore, a turbo multi-user detector/decoder (MUDD) is proposed for the LDS-OFDM receiver. We show how the turbo MUDD is tuned using EXIT charts analysis. By tuning the turbo-style processing, the turbo MUDD can approach the performance of optimum MUDD with a smaller number of inner iterations. Using the suggested design guidelines in this paper, we show that the proposed structure brings about 2.3 dB performance improvement at a bit error rate (BER) equal to 10-5 over conventional LDS-OFDM while keeping the complexity affordable. Simulations for different scenarios also show that the LDS-OFDM outperforms similar well-known multiple access techniques such as multi-carrier code division multiple access (MC-CDMA) and group-orthogonal MC-CDMA

A new design model for adhesive joints used to bond FRP laminates to steel beams

The strengthening and repair of existing structures using bonded carbon fiber reinforced polymer, CFRP, laminates has attracted a great deal of attention in the past two decades. Investigations clearly indicate the great potential of this method for restoring the capacity of corroded steel beams and improving their fatigue life. One important issue regarding the use of this technique in strengthening steel structures is the design of adhesive joints used to bond FRP laminates to steel substrates. Very limited research work has been conducted in this area and, at the present time, there is a lack of suitable design models for FRP-strengthened steel members. This paper is mainly concerned with a proposal for and verification of a new design model for adhesive joints used to bond FRP laminates to steel beams for strengthening and repair purposes. Quasi-static tests were performed on steel plate and full-scale beam specimens bonded with CFRP laminates to evaluate the new design model proposed in this study. The failure, in all specimens, took place at the steel-adhesive interface. The new design model presented in this paper was found to be accurate in terms of predicting the ultimate load and failure mode of the joints