Assessment of Glomerular Filtration Rates by Cockcroft-Gault and Modification of Diet in Renal Disease Equations in a Cohort of Omani Patients

Objectives: Glomerular filtration rate (GFR) is the best index of renal function and is frequently assessed by corrected creatinine clearance (CCLcr). The limitations of CCLcr have inspired researchers to derive easy formulas to estimate GFR, with Cockcroft-Gault (C-G) and the modification of diet in renal disease (MDRD) being the most widely used. This study aimed to evaluate the validity of these equations by finding the relation between CCLcr and estimated GFR (eGFR) by C-G, modified C-G and MDRD equations. Methods: From 2007 to 2011, 158 subjects were analysed for serum creatinine and CCLcr at Bowsher Polyclinic, Muscat, Oman. The C-G equation was used to obtain eGFRC-G which was adjusted to body surface area (BSA) to obtain eGFRmC-G, and the MDRD equation was used to obtain eGFRMDRD. The eGFRMDRD, eGFRmC-G and eGFRC-G were then compared to CCLcr. Results: The eGFRMDRD, eGFRmC-G and eGFRC-G significantly correlated with CCLcr, with a slightly stronger correlation with eGFRMDRD (r = 0.701, 0.658 and 0.605, respectively). A receiver operating characteristic curve analysis showed that the diagnostic accuracy of eGFRMDRD for diagnosing chronic kidney disease (CKD) was higher than that of eGFRmC-G, which in turn was higher than that of eGFRC-G (area under the curve was 0.846, 0.831, and 0.791; cut-off limits were 61.9, 58.3 and 59.5, respectively). Conclusion: C-G and MDRD equations can be an alternative to the CCLcr test for assessing GFR, thus avoiding the need for the cumbersome and expensive GFR test. The MDRD formula had greater validity than the C-G equation and the C-G equation validity was improved by an adjustment to BSA

Parental Attitude towards the Prescription of Psychotropic Medications for Mental Disorders in Children in a Tertiary Care University Hospital in Oman

Objectives: This study investigated parental attitudes towards psychotropic drugs for children's mental disorders. Methods: A questionnaire was distributed to parents of children attending a child psychiatry clinic at a tertiary hospital in Muscat, Oman. Similarly, in a small proportion, other caregivers filled out the questionnaire in case the child attended with them. The questionnaire comprised questions regarding parents' opinions, and attitudes about psychotropic medications use. The logistic regression model was used to identify the risk factors associated with parents who prefer to consult a folk healer (FH) for children with mental disorders. Results: A total of 299 parents agreed to participate in the study. The majority of them (81.6%, n=244) agreed that they would give their child psychotropic medications if necessary, but 25.4% of them (n=76) would consult a FH before consulting a psychiatrist if their child experienced psychiatric symptoms. Married parents were 14 times (OR=14.5, p=0.011) more likely to consult a FH than were separated or divorced parents. Caregivers with a monthly income below 500 OMR and between 500-1,000 OMR were two times (OR=2.5, p=0.016) and three times (OR=3.2, p<.001), respectively, more likely to consult a FH than those with a monthly income of more than 1,000 OMR. Parents who disagreed with giving psychotropic medications to their children were three times (OR=3.7, p<.001) more likely to consult a FH than were parents who agreed to give psychotropic medications to their children if necessary. Conclusion: Most parents agreed to give their children psychotropic medications if it were deemed necessary. However, a sizeable proportion of parents and caregivers preferred to consult a FH before accessing mental health services. Keywords: Parents; Children; Attitudes; Psychotropic Drugs; Oma

Role of NGOs in motivating youths to volunteer work related to the social and economic returns in the Sultanate of Oman

This study aims to investigate the role of NGOs in motivating youths to volunteer work in the Sultanate of Oman. Also it analyzes the social and economic returns of youths’ volunteer work in civic societies and the facilities offered to them and the laws and regulations governing the work of volunteer in those societies. Qualitative approach used through collecting data from 90 interviewees represented of 85% of total population. Their responses were coded using (NVivo) program. The study result showed that there are 566 codes. Those codes were analyzed and showed that the social returns of youth volunteers provides more opportunities to them in developing their skills and socially empowering them through their participation in workshops conducted by those societies. Where the Governorate of Muscat coded higher percentage compare with the South Batinah and South Sharqiay Governorates. As for the economic returns, the results showed that it is still at low level. The study results showed there are other returns are linked to the development of society and groups related to the elderly and children. In accordance to facilities provided for youths volunteers where Dhofar governorate shows the highest percentage compared to other governorates. The study result also shows that there is a need for legislation to regulate voluntary work and preserve the rights of volunteers to ensure the continuity of youth’s participations in volunteer work. Upon the study results, many recommendations and suggestions were proposed

Clinical Features and Outcome of 65 Laboratory Confirmed Cases of H1N1 in Muscat, Sultanate of Oman

Objectives: Responding to Pandemic Influenza A (H1N1) virus alert in 2009, Ministry of Health (MoH), Sultanate Of Oman arranged task force to deal with the emergency. MOH published articles in newspapers, prepared guidelines and hospitals were assigned to admit patients of H1N1. All the patients suspected of H1N1 were admitted and isolated as per the guidelines. This report describes clinical features and outcomes of 65 laboratory confirmed cases of H1N1 in Muscat, Sultanate of Oman.Methods: From July to October 2009, 101 cases suspected of suffering from Pandemic Influenza A (H1N1) virus were admitted and isolated in Al Nahdha Hospital in Muscat. All the patients on admission were tested for H1N1, by real time reverse transcriptase polymerase chain reaction (RT-PCR). Immediately on admission, all of them were treated with Oseltamivir and antibiotics.Results: Of the 65 confirmed cases of H1N1, 53.84% were males. Age of patients varied from 14 to 60 years, while 53.7% were aged between 31 to 55 years. Results showed that 70.8% had underlying co-morbidity; among which diabetes mellitus and respiratory illness were common. The most common presenting symptoms were fever (95%) and cough (94%). Also, 20% of the patients had leucopenia and 10.8% leucocytosis. Deranged LFT was observed in 26 (42.6%) of cases while 14 (21.5%) had hypokalemia. One patient (0.01%) with underlying severe co-morbidity died. Two patients (3.1%) had ARDS (Acute Respiratory Distress Syndrome); both recovered. Radiological infiltration was documented in 84.6% of cases, with lower zone involvement as the common finding. Hospital stay was between 1 to 12 days, 49.2% of patients were discharged within 3 days.Conclusion: Mainly adult population was affected during this epidemic. H1N1 infection can lead to severe illness. Incidence of H1N1 was higher in patients with underlying co-morbidity. Timely intervention and administration of Oseltamivir may need to be modified

Teachers' cloud-based learning designs: the development of a guiding rubric using the TPACK framework

This study aimed to develop, validate, and trial a rubric for evaluating the cloud-based learning designs (CBLD) that were developed by teachers using virtual learning environments. The rubric was developed using the technological pedagogical content knowledge (TPACK) framework, with rubric development including content and expert validation of its items and levels. The rubric was revised based on various types of input including content validity and expert review. After many iterations of rubric implementation using two raters, the final version of the rubric was found to be reliable with high and substantial inter-rater reliability. This study provides a methodological contribution by developing and validating a rubric for teachers' cloud-based learning designs. It also provides a useful tool for evaluating the quality of teachers' CBLD, and assessing training needs

Fabrication and surface characterization of poly(4-aminodiphenylamine) film modified electrode and its application for lead and cadmium determination

Poly(4-aminodiphenylamine), Padpa, film was synthesized electrochemically on a glassy carbon electrode by potentiodynamic repetitive cycling of 4‑aminodiphenylamine (4adpa) in 1.0 M HCl. The mechanistic steps involved the oxidation of the protonated monomer to  diimine species which underwent dimerization process to form the mono-charged radical intermediate which was considered as the initiation step for the progress of polymerization. The electrochemical properties and surface morphology of the film modified electrode were characterized using electrochemical and various surface scanning techniques. The XPS data demonstrated the existence of (=N-) bonding responsible for polymer formation, while the AFM image revealed a uniform and symmetrical fiber structure with low energy dissipation. The modified electrode was primarily applied as an environmental sensor for the simultaneous and selective determination of Cd2+ and Pb2+ ions in water samples. The detection limit for Cd2+ and Pb2+ ions was found 25 and 14 mg L-1, respectively

Improved Sensitization of Zinc Oxide Nanorods by Cadmium Telluride Quantum Dots through Charge Induced Hydrophilic Surface Generation

This paper reports on UV-mediated enhancement in the sensitization of semiconductor quantum dots (QDs) on zinc oxide (ZnO) nanorods, improving the charge transfer efficiency across the QD-ZnO interface. The improvement was primarily due to the reduction in the interfacial resistance achieved via the incorporation of UV light induced surface defects on zinc oxide nanorods. The photoinduced defects were characterized by XPS, FTIR, and water contact angle measurements, which demonstrated an increase in the surface defects (oxygen vacancies) in the ZnO crystal, leading to an increase in the active sites available for the QD attachment. As a proof of concept, a model cadmium telluride (CdTe) QD solar cell was fabricated using the defect engineered ZnO photoelectrodes, which showed ∼10% increase in photovoltage and ∼66% improvement in the photocurrent compared to the defect-free photoelectrodes. The improvement in the photocurrent was mainly attributed to the enhancement in the charge transfer efficiency across the defect rich QD-ZnO interface, which was indicated by the higher quenching of the CdTe QD photoluminescence upon sensitization