Copolymerazaion of N-vinyl-2-pyrrolidon with Acrylic Acid and Methylmethacrylate

Low conversion copolymerization of N-vinyl-2-pyrrolidon M.W = (111.14) VP (monomer-1) has been conducted with acrylic acid AA and methymethacrylate MMA in ethanol at 70ºC , using Benzoyl peroxide BPO as initiator . The copolymer composition has been determined by elemental analysis. The monomer reactivity ratios have been calculated by the Kelen-Tudos and Finman-Ross graphical procedures . The derived reactivity ratios (r1 , r2 ) are : (0.51 , 4.85) for (VP / AA ) systems and (0.34 , 7.58) for (VP , MMA) systems , and found the reactivity ratios of the monomer AA , MMA is mor than the monomer VP in the copolymerization of (VP / AA) and (VP /MMA) systems respectly . The reactivity ratios values were used for microstructures calculation

Synthesis and Characterization of New 2-Quinolone Sulfonamide Derivatives

A series of new 2-quinolone derivatives linked to benzene sulphonyl moieties were performed by many steps: the first step involved preparation of different coumarins (A1,A2) by condensation of different substituted phenols with ethyl acetoacetate. The compound A1 was treated with nitric acid to afford two isomers of nitrocoumarin derivatives (A3) and (A4). The prepared compounds (A2, A3) were treated with hydrazine hydrate to synthesize different 2-quinolone compounds (A5,A6) while the coumarin treated with different amines gave compounds (A7,A8). Then the synthesized 2-quinolone compounds (A5-A8) treated with benzene sulphonyl chloride to afford new sulfonamide derivatives (A9-A12). The synthesized compounds were characterized by FT-IR, 1H-NMR, 13C-NMR spectra and by measurement some of their physical properties

Preparation and Identification of some new Pyrazolopyrin derivatives and their Polymerizations study

Preparation and Identification of some new Pyrazolopyrin derivatives and their Polymerizations stud

SYNTHESIS OF 4-BENZYLIDENE-2-(4-NITRO- PHENYL) - 4H-OXAZOL-5 -ONE DERIVATIVES WITH SUSPECTED BIOLOGICAL ACTIVITY

Oxazolones are five membered heterocyclic compounds containing nitrogen and oxygen as heteroatoms.The C-2 and C-4 positions of the oxazolone are crucial for their various biological activities. A series of oxazolone derivatives (1-11) have been synthesized as potential antibacterial and fungal agent. The newly synthesized compounds were evaluated. compounds have been prepared by the condensation of 4-nitrobenzoylglycine or benzoyl glycine  with aromatic aldehydes in the presence of ethanol, acetic anhydride and glacial acetic acid. The newly synthesized compounds were characterized by FTIR, ¹HNMR, C¹³NMR. Keywords:- Oxazolone, antibacterial and fungal agent, Synthesis

Novel quinazolinone derivatives: Synthesis and Antimicrobial Activity

Abstract: This work involves to synthesis novel organic compounds and studies their pharmacological. Approach: The title compound quinazolinone derivatives were prepared by reacting 3 amino of 3-amino-2-methylquinazolin-4(3H)-one (first) with various aldehydes and ketones, and second coupling through diazonium salts with resorcinol or with ethylacetoacetate then cyclized with hydrazine. The starting material 3-amino-2-methylquinazolin-4(3H)-one was synthesized by reacting hydrazine with 2-methyl-4H-benzo[d