3 research outputs found
Trichodysplasia Spinulosa
Trichodysplasia spinulosa (TS) is a unique, rare clinical and histological dermatologic entity described mainly in setting of immunosuppression. It is caused by a novel human polymoavirus, trichodysplasia spinulosa-associated polyomavirus (TSPyV). We report a biopsy-proven case of TS in a renal transplant patient presented to dermatology outpatient clinic in Montreal, Canada in 2015. Reduction of immunosuppression and/or anti-viral therapy is the main therapeutic strategies used to treat such cases. Our patient was managed with valgancyclovir with no obvious response. Subsequently, a trial of topical imiquimod was commenced. Awareness of TS can prompt early diagnosis and management to prevent possible complications.
Keywords: Trichodysplasia spinulosa, immunosuppression, organ-trasplant, human polyomavirus