43 research outputs found

    IMPLEMENTASI KEBIJAKAN RETRIBUSI TEMPAT REKREASI PARIWISATA DAN TEMPAT OLAHRA DALAM PENINGKATAN PENDAPATAN ASLI DAERAH DI KABUPATEN SUKABUMI (Studi kasus tempat rekreasi pariwisata pantai Ujung Genteng)

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    The title of this research is "Implementation of Retribution Site of Place of Reception and Place of Increase of Original Income (PAD) in Sukabumi Regency (case study of Ujung Tent beach recreation area). In the implementation of research to determine the factors that affect tourism companies in Ujung Genteng Regency. using the theory of Van Metter and Van Horn. This study uses a qualitative method. With 7 wounded informers and techniques, collecting data, interviews, documentation. The data validity testing procedure is done by source triangulation. The process of data analysis using a model proposed by Miles and Huberman. The result of the research shows that Implementation of Retribution Site of Place of Reception and Place of Indigenous Population (PAD) In Sukabumi Regency (case study of Ujung Gading Beach recreation place) has been running well, marked with the target of original income of existing area at Ujung Genteng beach has reached target realization. The methods and objectives, sources, characteristics of implementers, attitudes and trends (Disposition) of implementers, inter-organizational communication, and implementation, environmental, social, and political activities, each of which is good in its implementation

    In Silico Analysis of Single Nucleotide Polymorphism (SNPs) in Human β-Globin Gene

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    Single amino acid substitutions in the globin chain are the most common forms of genetic variations that produce hemoglobinopathies- the most widespread inherited disorders worldwide. Several hemoglobinopathies result from homozygosity or compound heterozygosity to beta-globin (HBB) gene mutations, such as that producing sickle cell hemoglobin (HbS), HbC, HbD and HbE. Several of these mutations are deleterious and result in moderate to severe hemolytic anemia, with associated complications, requiring lifelong care and management. Even though many hemoglobinopathies result from single amino acid changes producing similar structural abnormalities, there are functional differences in the generated variants. Using in silico methods, we examined the genetic variations that can alter the expression and function of the HBB gene. Using a sequence homology-based Sorting Intolerant from Tolerant (SIFT) server we have searched for the SNPs, which showed that 200 (80%) non-synonymous polymorphism were found to be deleterious. The structure-based method via PolyPhen server indicated that 135 (40%) non-synonymous polymorphism may modify protein function and structure. The Pupa Suite software showed that the SNPs will have a phenotypic consequence on the structure and function of the altered protein. Structure analysis was performed on the key mutations that occur in the native protein coded by the HBB gene that causes hemoglobinopathies such as: HbC (E→K), HbD (E→Q), HbE (E→K) and HbS (E→V). Atomic Non-Local Environment Assessment (ANOLEA), Yet Another Scientific Artificial Reality Application (YASARA), CHARMM-GUI webserver for macromolecular dynamics and mechanics, and Normal Mode Analysis, Deformation and Refinement (NOMAD-Ref) of Gromacs server were used to perform molecular dynamics simulations and energy minimization calculations on β-Chain residue of the HBB gene before and after mutation. Furthermore, in the native and altered protein models, amino acid residues were determined and secondary structures were observed for solvent accessibility to confirm the protein stability. The functional study in this investigation may be a good model for additional future studies

    Cavity QED and atom optics in planar dielectric/metallic structures

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    Assessing movement quality on straight leg raise using neural networks and data science

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    Wearable sensors used to measure position/orientation and acceleration during exercise for knee and hip osteoarthritis have the potential to enhance physiotherapy rehabilitation through the personalisation of exercise. This data can be used to monitor exercise performance from the home and provide personalised feedback based on the quality of movement during the exercises outside of the clinical setting. Data science can be implemented to objectively characterise the quality of the movement patterns. This is achieved with intelligent algorithms that identify the movement quality based on orientations and acceleration data, which represent common feedback given by physiotherapists. These algorithms aim to recognize the underlying relationships inside the data, emulating the way the human brain functions. This results in a classification system that can distinguish between a good and a difficult movement.This study aimed to develop a neural network to assess the quality of movement during one rehabilitation exercise, the straight leg raise. This exercise was selected because it is a commonly prescribed non-weight bearing exercise used early in a rehabilitation programme

    Nanometer scale microscopy via graphene plasmons

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    Novel and advantageous systems and methods for performing nanometer-scale microscopy using graphene plasmons (GPs) are provided. Sub-diffraction microscopy can be achieved, taking advantage of the extremely small plasmon wavelength and low dissipation of GPs. Nanometer-scale resolution can be obtained under very weak light intensity, which is especially important in the imaging of biological systems.U

    Sub-wavelength lithography via Rabi oscillations

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    A sub-wavelength photolithographic method includes exposing a photoresist material to a stimulating electromagnetic source prior to further exposing the photoresist material to a dissociating electromagnetic source. The stimulating electromagnetic source induces Rabi oscillations in the photoresist material between a first molecular state and an excited molecular state. The subsequent exposure of the photoresist material to the dissociating electromagnetic source dissociates only those molecules that are in the excited state, altering the properties of the photoresist material in zones of excited state molecules. The resulting patterns therefore depend on the spatial distribution of the zones of excited state molecules induced by the stimulating electromagnetic source. The properties of the stimulating electromagnetic source are controlled to achieve a desired spatial distribution of zones of excited state molecules of the photoresist material.U

    Resonance fluorescence localization microscopy with sub-wavelength resolution

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    The resonance fluorescence spectrum of a number of two-level atoms is driven by a gradient coherent laser field. In the weak dipole-dipole interaction region (separation less than ?/50), a very strong laser field may be applied such that the Rabi frequency is much larger than the dipole-dipole interaction energy. From the spectrum, the positions of each atom may be determined by just a few measurements. This sub-wavelength microscopy scheme is entirely based on far-field technique and it does not require point-by-point scanning, which makes the method more time-efficient. When two atoms are very close to each other (less than ?/50), the position information for each atom may still be obtained with very high accuracy provided that they are not too close to other atoms. The method may be extended to an arbitrarily large region without requiring more peak laser power and only a few measurements are required.U

    Nanometer scale microscopy via graphene plasmons

    No full text
    Novel and advantageous systems and methods for performing nanometer-scale microscopy using graphene plasmons (GPs) are provided. Sub-diffraction microscopy can be achieved, taking advantage of the extremely small plasmon wavelength and low dissipation of GPs. Nanometer-scale resolution can be obtained under very weak light intensity, which is especially important in the imaging of biological systems.U
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