Thiosemicarbazone organocatalysis:Tetrahydropyranylation and 2-deoxygalactosylation reactions and kinetics-based mechanistic investigation

Thiosemicarbazones are introduced as a new class of highly tunable and efficient organocatalysts. We showcase this by studies of the tetrahydropyranylation reaction, where insights to the mechanism was achieved by a double Hammett analysis of both the substrate and the catalyst.</p