Simple-Box-9 coil system: A novel approachto design of a square coil system for producing uniform magnetic fields

This paper presents a novel approach for the design of square coil system, through considerations of a conventional square coil system. This simple approach allows us to design a coil system which contains a greater number of coils. From this design method, we introduce a new structure system of same-sized square coils, Simple-Box-9. The constant coil spacing is a fourth-part of the side length of the coil, and the number of windings is 2/1/1/1/1/1/1/1/2. From numerical calculations and experiments, it is shown that Simple-Box-9 can achieve the best uniformity compared with conventional square coil systems.ArticleMaterials Science Forum. 670:275-283 (2010)journal articl

Simple-Box-9 Coil System: A Novel Approach to Design of a Square Coil System for Producing Uniform Magnetic Fields

This paper presents a novel approach for the design of square coil system, through considerations of a conventional square coil system. This simple approach allows us to design a coil system which contains a greater number of coils. From this design method, we introduce a new structure system of same-sized square coils, Simple-Box-9. The constant coil spacing is a fourth-part of the side length of the coil, and the number of windings is 2/1/1/1/1/1/1/1/2. From numerical calculations and experiments, it is shown that Simple-Box-9 can achieve the best uniformity compared with conventional square coil systems.ArticleMaterials Science Forum. 670:275-283 (2010)journal articl

Asymmetrically traveling auroral surges in the northern and southern hemisphere

The Tenth Symposium on Polar Science/Ordinary sessions: [OS] Space and upper atmospheric sciences, Wed. 4 Dec. / Institute of Statistics and Mathematics (ISM) Seminar room 2 (D304) (3rd floor

Association between Big Five Personality Traits and Participation in Cardiac Rehabilitation in Japanese Patients with Cardiovascular Disease: A Retrospective Cohort Study

Cardiac rehabilitation (CR) remains underutilised, despite its established clinical benefit. A personality traits assessment may help promote CR implementation, as they are determinants of health-related behaviour. This study aimed to examine the association between the Big Five personality traits and outpatient CR participation in patients with cardiovascular disease (CVD) after discharge. This retrospective cohort study included 163 patients aged <80 years, who underwent inpatient CR when hospitalised for CVD. The Big Five personality traits (conscientiousness, neuroticism, openness, extraversion, and agreeableness) of each patient were evaluated at discharge, using the Japanese version of the Ten-Item Personality Inventory. We examined the relationship of each personality trait with non-participation in outpatient CR and dropout within three months, using logistic regression analysis. Out of 61 patients who initiated the outpatient CR, 29 patients dropped out, leaving us with 32 subjects. The logistic regression analysis results showed that high conscientiousness was associated with non-participation in CR. The primary reason for this was a lack of motivation. Conversely, low conscientiousness and high openness were predictors of dropout. This study suggests that the assessment of the Big Five personality traits, especially conscientiousness and openness, can help improve health communication with patients to promote outpatient CR participation after discharge

Cell-Based Double-Screening Method to Identify a Reliable Candidate for Osteogenesis-Targeting Compounds

Small-molecule compounds strongly affecting osteogenesis can form the basis of effective therapeutic strategies in bone regenerative medicine. A cell-based high-throughput screening system might be a powerful tool for identifying osteoblast-targeting candidates; however, this approach is generally limited with using only one molecule as a cell-based sensor that does not always reflect the activation of the osteogenic phenotype. In the present study, we used the MC3T3-E1 cell line stably transfected with the green fluorescent protein (GFP) reporter gene driven by a fragment of type I collagen promoter (Col-1a1GFP-MC3T3-E1) to evaluate a double-screening system to identify osteogenic inducible compounds using a combination of a cell-based reporter assay and detection of alkaline phosphatase (ALP) activity. Col-1a1GFP-MC3T3-E1 cells were cultured in an osteogenic induction medium after library screening of 1280 pharmacologically active compounds (Lopack1280). After 7 days, GFP fluorescence was measured using a microplate reader. After 14 days of osteogenic induction, the cells were stained with ALP. Library screening using the Col-1a1/GFP reporter and ALP staining assay detected three candidates with significant osteogenic induction ability. Furthermore, leflunomide, one of the three detected candidates, significantly promoted new bone formation in vivo. Therefore, this double-screening method could identify candidates for osteogenesis-targeting compounds more reliably than conventional methods