Integrating Divergent Epistemologies of the Two Influential Views on Organizational Knowledge Creation

This paper integrates the divergent epistemologies of the organizational learning view and the knowledge-creation view on how new knowledge is created in organizations. The former view adopts an information-processing perspective and emphasizes the importance of deep knowledge and higher-level learning, whereas the latter view adopts a social constructionist perspective and stresses the importance of tacit knowledge and interactive dialogue. The paper’s integration uses the theorization of knowledge levels; specifically, the shifts and movements in knowledge trajectories and the inverse relationship between the degree of tacitness and explicitness. The paper contributes greater coherence in our understanding of knowledge creation as well as generates new meaning/insights. The paper concludes by highlighting potential interpretations/insights and implications, before presenting limitations and future research directions.</p

Adequacy of phosphodiesterase inhibitor in prevention and treatment of LPS induced organ failure in BALB/c mice

Background: Even though with immense improvement and extensive understanding of pathophysiology of sepsis induced organ failure and affected population, it continues to put hundreds of people worldwide to eternal sleep due to lack of targeted therapy. Newer treatment modalities is the dire need of time. The present study was aimed to ascertain the adequacy of phosphodiesterases inhibitor - pentoxifylline (75mg/kg i.p) in endotoxin/LPS induced hepatotoxicity in BALB/c mice.Methods: The number of animals in each group was six. Endotoxin/lipopolysaccharides induced hepatotoxicity was reproduced in mice by giving lipopolysaccharide of serotype E. coli intraperitoneally. To ascertain the Preventive role, pentoxifylline was administered forehand LPS injection whereas therapeutic potential adjuged via post LPS delivering. The extent of liver damage was evaluated through serum alanine aminotransferases (ALT) and aspartate aminotransferase (AST) estimation along with histopathological examination of liver tissue.Results: Results set forth that serum ALT, AST levels and histological alteration abated considerably (p ≤0.05) both in animals subjected to pentoxifylline pre and post-treatment.Conclusions: Pentoxifylline set up promising results in endotoxin induced hepatotoxicity and can be used therapeutic adjuncts to conventional treatment strategies in sepsis induced liver failure

Improving investment promotion agencies performance in attracting foreign direct investment

Purpose This study aims to investigate how investment promotion agencies (IPAs) attract funds effectively from emerging to established countries. Design/methodology/approach A qualitative action research (AR) study with data collected from focus groups and semi-structured interviews, observation and journaling. Comparative case studies are also presented to provide an external perspective to the researchers’ internal action researcher positions. Findings The research identifies four main factors that impact IPAs’ effectiveness in seeking a strategic asset in the UK from a developing country, China. The factors are policy advocacy, targeting industry, regional strategy and cultural adaption, which provide positive and significant influences on IPAs’ effectiveness. Research limitations/implications Little research has been published about the roles of IPAs in attracting foreign direct investment (FDI) from a developing to a developed country. The study uses an AR approach and case studies, which have not previously been used to investigate IPAs’ performance. The study extends the sparse extant research and provides insights into what influences the performance of IPAs, thus contributing to knowledge and practice. Practical implications The findings provide insights into the ways in which IPAs influence FDI flows. The research contributes to discipline knowledge and practice by identifying factors influencing funding in a non-traditional manner, that is from a developing to a developed country. Originality/value Little research has been published about the roles of IPAs in attracting FDI from a developing to a developed country. The study uses an AR approach and case study, which have not previously been used to investigate IPAs’ performance. The study extends the sparse extant research and provides insights into what influences the performance of IPAs, thus contributing to knowledge and practice. </jats:sec

Wi-Fi Fingerprinting Based Room Level Indoor Localization Framework Using Ensemble Classifiers

Over the past decennium, Wi-Fi fingerprinting based indoor localization has seized substantial attention. Room level indoor localization can enable numerous applications to increase their diversity by incorporating user location. Real-world commercial scale deployments have not been realized because of difficulty in capturing radio propagation models. In case of fingerprinting based approaches, radio propagation model is implicitly integrated in the gathered fingerprints providing more realistic information as compared to empirical propagation models. We propose ensemble classifiers based indoor localization using Wi-Fi fingerprints for room level prediction. The major advantages of the proposed framework are, ease of training, ease to set up framework providing high room-level accuracy with trifling response time making it viable and appropriate for real time applications. It performs well in comparison with recurrently used ANN (Artificial Neural Network) and kNN (k-Nearest Neighbours) based solutions. Experiments performed showed that on our real-world Wi-Fi fingerprint dataset, our proposed approach achieved 89% accuracy whereas neural network and kNN based best found configurations achieved 85 and 82% accuracy respectively

A multi-level perspective on trust, collaboration and knowledge sharing cultures in a highly formalized organization

Purpose The purpose of this study is to investigate organizational culture’s perceived importance and practice as it unfolds across hierarchal layers of a formalized organization. Organizational culture is important in innovation and change and becomes significant if its importance and practice are shared across all levels of an organization. Highly formalized organizations are not an exception to this. Yet, there is a shortage of empirical evidence on how the organizational culture’s perceived importance and practice unfold across the senior-management, middle-management and operational levels of a formalized organization. Design/methodology/approach Applying a theoretical frame incorporating information asymmetry, knowledge sharing and cultural participation, this paper examined three important facets of culture, namely, trust, collaboration and knowledge-sharing. Using a Jordanian bank’s case study, this paper collected data using a mixed-methods approach; quantitative to identify variations across levels and, subsequently, qualitative to explore the nuanced patterns in the perceived importance and practice of the three facets across different organizational levels in the context of a formalized organization. Findings The findings suggest that the importance and practice of the three cultural facets are shared, as well as differentiated across organizational levels based on purposiveness, person/situation-dependency and nature of work and nature/relevance of knowledge. Originality/value Using a multi-level lens provided insight not yet gained by current work in the field. This allowed us to unearth nuanced differences in the perception of organizational culture across organizational hierarchies. The paper contributes to the scholarship on organizational culture in the context of formalized organizations and to managerial practice by offering insights on how a shared practice of trust, collaboration and knowledge sharing is distributed across organizational levels, not captured before. This paper also suggests propositions related to each of three cultural facets, not spelled out before. </jats:sec

Women's leadership gamut in Saudi Arabia's higher education sector

This paper explores women's leadership in Saudi Arabia's three university settings—gender segregated (women or men-only), unsegregated (co-educational) and the majority of partially segregated universities where women's campuses exist within male-dominated universities. While Saudi Arabia's accelerated reforms are creating new opportunities for women's leadership, these are not reflected in the higher education sector yet. In adopting a feminist institutional theory perspective, this study employed a feminist qualitative approach, including 14 semi-structured interviews in Saudi Arabia's three university settings. The findings revealed that the barriers to women's leadership were most significant within the partially segregated universities, rendering women leaders as effectively powerless. In contrast, women's leadership flourished in the women-only university setting. As such, the findings suggest that the dominating partially segregated model is ineffective and problematic for women's leadership, and contradict the dominant view that gender segregation disempowers women. These insights have implications for the transformation of Saudi Arabia's higher education sector, aligned with the Kingdom's Vision 2030 policy

Absorptive capacity and performance: The role of customer relationship and technological capabilities in high-tech SMEs

This study focuses on how the interplay between a firm&apos;s absorptive capacity (ACAP), and its technological and customer relationship capability contributes to its overall performance. Using structural equation modeling in a sample of 158 firms (316 questionnaires, two respondents per firm) from South Korea&apos;s semiconductor industry, we find that a firm&apos;s ACAP leads to better performance in terms of new product development, market performance and profitability when used in combination with the firm&apos;s capability to engage state of the art technologies in its new product development program (NPD) (technological capability) as well as cultivate strong customer relationships to gain customer insight in NPD (customer relationship capability). By highlighting the interactive nature of absorptive capacity&apos;s antecedents and how these relate to firms&apos; performance, this study contributes to the understanding of the role of ACAP as a mechanism for translating external knowledge into tangible benefits in high-tech SMEs, thus leading to important theoretical and practical implications

Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: Multispecialty, prospective cohort study in 25 countries

Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P \u3c 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (β coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely

Interactions between selected bile salts and Triton X-100 or sodium lauryl ether sulfate

<p>Abstract</p> <p>Background</p> <p>In order to develop colloidal drug carriers with desired properties, it is important to determine physico-chemical characteristics of these systems. Bile salt mixed micelles are extensively studied as novel drug delivery systems. The objective of the present investigation is to develop and characterize mixed micelles of nonionic (Triton X-100) or anionic (sodium lauryl ether sulfate) surfactant having oxyethylene groups in the polar head and following bile salts: cholate, deoxycholate and 7-oxodeoxycholate.</p> <p>Results</p> <p>The micellization behaviour of binary anionic-nonionic and anionic-anionic surfactant mixtures was investigated by conductivity and surface tension measurements. The results of the study have been analyzed using Clint's, Rubingh's, and Motomura's theories for mixed binary systems. The negative values of the interaction parameter indicate synergism between micelle building units. It was noticed that Triton X-100 and sodium lauryl ether sulfate generate the weakest synergistic interactions with sodium deoxycholate, while 7-oxodeoxycholate creates the strongest attractive interaction with investigated co-surfactants.</p> <p>Conclusion</p> <p>It was concluded that increased synergistic interactions can be attributed to the larger number of hydrophilic groups at α side of the bile salts. Additionally, 7-oxo group of 7-oxodeoxycholate enhance attractive interactions with selected co-surfactants more than 7-hydroxyl group of sodium cholate.</p

Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries

Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P &lt; 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely