Homogeneous and Isotropic space-time, Modified torsion field and Complete cosmic scenario

The paper deals with cosmological solutions describing different phases of the Universe for the homogeneous and isotropic FLRW model of the Universe with torsion. Normally, torsion field is not suitable for maximally symmetric space time model. However, one may use a specific profile of vectorial torsion field, derived from a scalar function. By proper choices of the torsion scalar function, it is shown that a continuous cosmic evolution starting from the emergent scenario to the present late time acceleration is possible. Also thermodynamics of the system is analyzed and equivalence with Einstein gravity is discussed.Comment: 8 pages,4 figure

Habit nail tic disorder: onychotillomania involving thumbs and toes responding to fluoxetine

Habit nail tic disorder is a type of nail dystrophy caused by repetitive trauma to the nail matrix. It is a body-focused repetitive behavior that is commonly reported among adults and may or may not be associated with obsessive-compulsive behavior. In this report, we present a case of a 12-year-old adolescent girl who had a central furrow with longitudinal ridges running parallel from the proximal to the distal end of both her thumbnails and toenails, giving them a "washboard" appearance and diagnosed as habit nail tic disorder, and treatment involved fluoxetine 20 mg and the application of permeable adhesive tape to protect the nails from external trauma. There was a positive response observed two months after the beginning of the treatment and the nail matrix resolved spontaneously

Observational constraints on f(R, T) gravity with f(R,T)=R+h(T)f(R,T) = R + h(T) f ( R , T ) = R + h ( T )

Abstract The present cosmological model deals with modified f(R, T) gravity theory with $$f(R,T)=R+h(T)$$ f ( R , T ) = R + h ( T ) in the background of homogeneous and isotropic FLRW space-time model. Four choices of h(T) have been studied and examined from two observational data sets. It is found that model III, namely, the linear combination of power law and logarithmic form is more consistent with observed data than the others. However, all four considered models are a worse fit than the LCDM model

Theoretical and observational prescription of warm-inflation in FLRW universe with torsion

Abstract The paper deals with Warm Inflationary scenario in FLRW with torsion both from theoretical and observational point of view. In the background of flat FLRW model the Hubble parameter is found to be proportional to the torsion function and warm inflation is examined both in weak and strong dissipation regimes for the power law choice of potential using slow-roll approximation with quasi-stable criteria for radiation. The slow-roll parameters, no.of e-folds, scalar spectral index, and tensor-to-scalar ratio are determined in the present model for mainly three choices of the dissipation coefficient $$\Gamma$$ Γ using the Planck data set. Finally, we focus on single-field chaotic quartic potential with the above choices of the dissipation coefficient to confront the warm inflation observational predictions directly with the latest observational data set

Metabolism of Phytochemicals

Several phytochemicals have been developed as medicinal compounds. Extensive research has recently been conducted on phytochemicals such as curcumin, resveratrol, catechin, gallic acid, humulone, quercetin, rutin, diosgenin, allicin, gingerenone-A, caffeic acid, ellagic acid, kaempferol, isorhamnetin, chlorogenic acid, and others. All of these phytochemicals are metabolized in the biological system. To study the metabolic pathways of phytochemicals, studies are done using both in vitro and in vivo techniques. Metabolism is critical in determining phytochemical bioavailability, pharmacokinetics, and effectiveness. Metabolism can occur in organs such as the intestine, liver, gut, and spleen. The metabolic process is aided by a variety of enzymes, including cytochrome P450 enzymes found in the organs. This study outlines a few phytochemicals metabolic pathways. Tannic acid, ellagic acid, curcumin, quercetin, and resveratrol are selected and explained as examples

Sodium fluoride induces skeletal muscle atrophy via changes in mitochondrial and sarcomeric proteomes.

Sodium Fluoride (NaF) can change the expression of skeletal muscle proteins. Since skeletal muscle is rich in mitochondrial and contractile (sarcomeric) proteins, these proteins are sensitive to the effects of NaF, and the changes are dose-and time-dependent. In the current study, we have analysed the effect of high concentrations of NaF (80ppm) on mouse skeletal muscle at two different time points, i.e., 15 days and 60 days. At the end of the experimental time, the animals were sacrificed, skeletal muscles were isolated, and proteins were extracted and subjected to bioinformatic (Mass Spectrometric) analysis. The results were analysed based on changes in different mitochondrial complexes, contractile (sarcomeric) proteins, 26S proteasome, and ubiquitin-proteasome pathway. The results showed that the mitochondrial proteins of complex I, II, III, IV and V were differentially regulated in the groups treated with 80ppm of NaF for 15 days and 60 days. The network analysis indicated more changes in mitochondrial proteins in the group treated with the higher dose for 15 days rather than 60 days. Furthermore, differential expression of (sarcomeric) proteins, downregulation of 26S proteasome subunits, and differential expression in proteins related to the ubiquitin-proteasome pathway lead to muscle atrophy. The differential expression might be due to the adaptative mechanism to counteract the deleterious effects of NaF on energy metabolism. Data are available via ProteomeXchange with identifier PXD035014