Dekan:

Synthesis and physico-chemical studies on dithiolene complexes of the closed-shell (d 10) metals and trivalent lanthanide ion

zur Erlangung des Grades

First and foremost, I would like to dedicate my thanks to my supervisor Prof. Dr. Volkhard Helms for offering me the opportunity to work in his group. During the last years, he supported me with fruitful discussions, valuable suggestions, and his encouragement. Especially, I am thankful for offering me the opportunity to attend many interesting conferences and workshops. In this context, I would also like to thank the Center for Bioinformatics, Saar for the initial funding. I want to thank my co-workers, especially Tihamér Geyer for his technical support and assistance and the “Coffee Club ” for very enjoyable scientific, as well as non-scientific discussions. Furthermore, I thank Jan Fuhrmann and Dirk Neumann who kindly provided their BALLPass implementation to us and Anja Berwanger and Prof. Dr. Rita Bernhardt for giving me interesting insights into the “in vitro ” world of Biochemistry. Last, but now least I want to specially thank my friends Benjamin Eckert, Lars Steinbrück, Dorothea Emig, Peter Walter, and Andreas Schlicker for revising my thesis and my family for always believing in me. Protein-protein interactions play a pivotal role in most biological processes. Especially their functio

Dr. Holger KohlmannList of abbreviations Abbreviation Full Name

AAA a.u.

Datum des Promotionskolloquiums: 29. Juni 2007

We describe basic concepts and software architectures for the integration of shallow and deep (linguistics-based, semantics-oriented) natural language processing (NLP) components. The main goal of this novel, hybrid integration paradigm is improving robustness of deep processing. After an introduction to constraint-based natural language parsing, we give an overview of typical shallow processing tasks. We introduce XML standoff markup as an additional abstraction layer that eases integration of NLP components, and propose the use of XSLT as a standardized and efficient transformation language for online NLP integration. In the main part of the thesis, we describe our contributions to three hybrid architecture frameworks that make use of these fundamentals. SProUT is a shallow system that uses elements of deep constraint-based processing, namely type hierarchy and typed feature structures. WHITEBOARD is the first hybrid architecture to integrate not only part-of-speech tagging, but also named entity recognition and topological parsing, with deep parsing. Finally, we present Heart of Gold, a middlewar