Proximate composition, structural characterization and phytochemical screening of the seed oil of Adenanthera pavonina linn

Adenanthera pavonina is leguminous species which is a perennial and non-climbing tree which is a highly valuable plant for food, drink, and traditional medicine. The Adenanthera pavonina Linn Seed was obtained in our institution premises. This present study was targeted at evaluating proximate analysis, phytochemical determination, a physicochemical parameter of the spectroscopically characterized oil sample of Adenanthera pavonina. The oil which was extracted by standard method had percentage yield of 15.36%. The phytochemical screening of the oil revealed the presence of saponin, alkaloid, and terpenoids. Proximate analysis result unveiled that seed oil of Adenanthera pavonina Linn had an appreciable quantity of protein 27.72%, Crude fiber 5.82 and Ash contents 2.51. It also showed the moisture content, organic matter, carbohydrate, pH and Refractive index to be 13.34%, 97.49% 54.36%, 5.96 and 1.62 respectively. The mineral determination showed that the seed oil contained Manganese (0.001 ± 0.0002 %), Iron (13.52 mg/kg), while Potassium (K), Sodium (Na), Nickel (Ni), Chromium (Cr), Cobalt (Co), Lead (Pb) and Cadmium (Cd) were below the detectable limit. The structure of the oil was elucidated using physicochemical analyses and spectral data which include FT-IR, UV, 1H- and 13C-NMR as well as mass spectral data. The spectroscopic data correlated well and was consistent with the proposed structure. The seed oil could provide access to increase dietary formulation owing to its high protein content. Keyword

Effect of polyol on multiple ligand capped silver alloyed nanobimetallic particles in tri-n-octylphosphine oxide and oleic acid matrices

The syntheses of Ag/M (M is Co, Ni, Pd, Pt and Ru) alloyed nanobimetallic particles in tri-noctylphosphine oxide and oleic acid matrices were successfully carried out by the successive reduction of ligand capped metal ions with polyols, which resulted in rapid precipitation of some fractal high index faceted hybrid Ag/M bimetal nanoparticles. The optical measurements revealed the existence of modified surface plasmon band and peak broadening resulting from reaction-limited growth processes of the metal sols, making it possible to monitor the changes spectrometrically. The bimetallic nanoparticles were further characterized by powder x-ray diffraction, x-ray photoelectron spectroscopy and electron microscopy techniques which confirmed the formation of novel core–shell and alloyed clusters. The Ag/M nanoparticles thus synthesized within TOPO/OA matrices indicated significant reduction potential as a result of their energy band gap 2.65–2.77eV which points to the fact that they could serve as reducing agents for electrocatalytic reaction

Facile synthesis, characterization and antimicrobial activity of 2-alkanamino benzimidazole derivatives

Benzimidazole derivatives are known to represent a class of medicinally important compounds which are extensively used in drug design and catalysis. A series of 2-substituted benzimidazole derivatives 10a-i was herein synthesized from the reaction of o-phenylenediamine with some amino acids using ameliorable pathway. The chemical structures of the synthesized compounds were confirmed by IR, UV, 1H-NMR, 13C-NMR, Mass spectral and analytical data. The compounds were investigated for their antimicrobial activity alongside gentamicin clinical standard. The results showed that this skeletal framework exhibited marked potency as antimicrobial agents. The most active compound was 1H-benzo[d]imidazol-2-yl)methanamine, 10a

Exploration of the chemistry and biological properties of pyrimidine as a privileged pharmacophore in therapeutics

The pyrimidine moiety is one of the most widespread heterocycles in biologically occurring compounds, such as nucleic acids components (uracil, thymine and cytosine) and vitamin B1. Due to its prebiotic nature to living cells in biodiversity, it is an highly privileged motif for the development of molecules of biological and pharmaceutical interest. This present work deals with the exploration of chemistry and medicinal diversity of pyrimidine which might pave way to long await discovery in therapeutic medicine for future drug design