Fast track fed-batch culture development for COVID-19 vaccine clinical study

Please click Additional Files below to see the full abstract

Remote Diagnosis of Architectural Heritage Based on 5W1H Model-Based Metadata in Virtual Reality

We propose a framework based on the 5W1H model-based metadata for remote diagnosis in virtual reality (VR). For this purpose, we suggest unique metadata composed of Point of Interest (POI)-extended anchor (xAnchor)-content for a context-aware service in virtual and augmented reality. We define the attributes of the metadata based on the 5W1H context for information retrieval according to the context in a remote diagnosis. Second, we propose the ontology-based linker metadata that express the relations between AR scenes and that retrieve external information. Moreover, we suggest heritage building information metadata for information retrieval according to context. For evaluation, we created a geo-tagged content tool and a remote diagnosis VR application. We conducted focus-group interviews and heuristic evaluations for remote diagnosis in VR to verify the methodology of this study. As a result, we found that experts were most satisfied with the functions that provide the contextualized information. This study contributes to the geospatial metadata for a context-aware service in VR/AR as well as the remote diagnosis framework to overcome the time-consuming problem of the existing remote diagnosis

Balancing Computation Loads and Optimizing Input Vector Loading in LSTM Accelerators

The long short-term memory (LSTM) is a widely used neural network model for dealing with time-varying data. To reduce the memory requirement, pruning is often applied to the weight matrix of the LSTM, which makes the matrix sparse. In this paper, we present a new sparse matrix format, named rearranged compressed sparse column (RCSC), to maximize the inference speed of the LSTM hardware accelerator. The RCSC format speeds up the inference by: 1) evenly distributing the computation loads to processing elements (PEs) and 2) reducing the input vector load miss within the local buffer. We also propose a hardware architecture adopting hierarchical input buffer to further reduce the pipeline stalls which cannot be handled by the RCSC format alone. The simulation results for various datasets show that combined use of the RSCS format and the proposed hardware requires 2x smaller inference runtime on average compared to the previous work.1

Isotope-production cross sections of residual nuclei in proton- and deuteron-induced reactions on

The isotope-production cross sections in p- and d-induced reactions on 93Zr at approximately 50 MeV/nucleon were measured by using the inverse-kinematics method at RIKEN RI Beam Factory. The measured data were compared with the previous experimental 93Zr + p, d at 105 and 209 MeV/nucleon data. This comparison represents that the isotopic distribution of production cross sections at 51 MeV p-induced reaction is appreciably different from those at 105 and 209 MeV. On the other hand, these three data sets show that the shape of isotopic distribution is similar in the case of the d-induced reaction. Also, the measured production cross sections were compared with the theoretical model calculations with Particle and Heavy Ion Transport code System (PHITS) version 3.10 in order to investigate the reproducibility of the models implemented in PHITS. The calculations well reproduced the experimental data even in such low incident energy, while several discrepancies were still seen as in the p- and d-induced reactions at 105 and 209 MeV/nucleon

Isotope-production cross sections of residual nuclei in proton- and deuteron-induced reactions on 93Zr at 50 MeV/u

The isotope-production cross sections in p- and d-induced reactions on 93Zr at approximately 50 MeV/nucleon were measured by using the inverse-kinematics method at RIKEN RI Beam Factory. The measured data were compared with the previous experimental 93Zr + p, d at 105 and 209 MeV/nucleon data. This comparison represents that the isotopic distribution of production cross sections at 51 MeV p-induced reaction is appreciably different from those at 105 and 209 MeV. On the other hand, these three data sets show that the shape of isotopic distribution is similar in the case of the d-induced reaction. Also, the measured production cross sections were compared with the theoretical model calculations with Particle and Heavy Ion Transport code System (PHITS) version 3.10 in order to investigate the reproducibility of the models implemented in PHITS. The calculations well reproduced the experimental data even in such low incident energy, while several discrepancies were still seen as in the p- and d-induced reactions at 105 and 209 MeV/nucleon