Tips and tricks in surgical management of maxillary sinus tumors

Background: 3% of head and neck carcinomas are sinonasal malignancy. Aim of study: Epidemiological evaluation of cancer maxilla in National Cancer Institute, Cairo University with emphasis on surgical strategy and intraoperative assessment of tumor extension that augment the oncologic, functional and esthetic results after resection of tumors of the maxilla. Patients and methods: 30 patients diagnosed as malignant maxillary tumor in the surgical department, National Cancer Institute, Cairo University in the period from October 2012 to May 2016. Results: In this study the most commonly recorded pathological diagnosis was squamous cell carcinoma 14 patients (46.7%). Most of the patients were presented with delayed presentation, in this study stage IVa was the most frequent stage (detected in 15 patients accounting for 50%). The overall survival of the studied cases was estimated using Kaplan-Meier survival estimate. It was of mean 22 months. The 2 year survival rate for the overall studied cases was 40% During the follow up period, local recurrence was recorded in 12 patients in this study (40%). Distant metastases were detected during follow up in two patients in this study (6.6%). Conclusion: Fine intraoperative surgical maneuvers can obtain secured resection margin (with special attention to adenoid cystic carcinoma); avoid postoperative functional complications like trismus, nasal regurgitation of food, epiphora or double vision finally enhance esthetic result

Multiple synchronous rhabdomyomas in the tongue and floor of the mouth: case report

Observation: A 61-year-old male patient presented with tongue and base floor of the mouth firm swelling with intact overlying mucosa with ballottement by bimanual palpation. Histopathological examination and immunodiagnosis revealed this mass as adult rhabdomyoma. Comments: Any tongue base or floor of the mouth mass with intact overlying mucosa should be approached by magnetic resonance imaging with great concern of rhabdomyoma

Endoscopic Evaluation after Conventional Adenoid Curettage

Introduction Adenoidectomy is one of the most common procedures performed by otolaryngologists. Traditional adenoid curettage is performed blindly, which can result in inadequate removal of the adenoid and injury to the surrounding structures

The Potential Utility of Circulating Oncofetal H19 Derived miR-675 Expression versus Tissue lncRNA-H19 Expression in Diagnosis and Prognosis of HCC in Egyptian Patients

Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide. Interestingly, lncRNA-H19 acts independently in HCC and influences miR-675 expressions. We aimed to assess the potential utility of tissue lncRNA-H19 versus miR-675 expressions as a non-invasive biomarker for HCC diagnosis and prognosis in Egyptian patients. Ninety-one HCC patients and 91 controls included in this study were investigated for expression of lncRNA-H19 and miR675 using RT-qPCR. Our results showed that the expression of lncRNA-H19 and microRNA-675 were higher in patients than in controls (p p p < 0.001, 0.001, respectively). Oncofetal H19-derived miR-675 expression could be considered a potential noninvasive diagnostic and prognostic biomarker, outstanding the performance of the expression of tissue lncRNA-H19 for HCC