10 research outputs found

    Association Between a Social-Business Eating Pattern and Early Asymptomatic Atherosclerosis.

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    BACKGROUND: The importance of a healthy diet in relation to cardiovascular health promotion is widely recognized. Identifying specific dietary patterns related to early atherosclerosis would contribute greatly to inform effective primary prevention strategies. OBJECTIVES: This study sought to quantify the association between specific dietary patterns and presence and extent of subclinical atherosclerosis in a population of asymptomatic middle-aged adults. METHODS: The PESA (Progression of Early Subclinical Atherosclerosis) study enrolled 4,082 asymptomatic participants 40 to 54 years of age (mean age 45.8 years; 63% male) to evaluate the presence of subclinical atherosclerosis in multiple vascular territories. A fundamental objective of this cohort study was to evaluate the life-style-related determinants, including diet, on atherosclerosis onset and development. We conducted a cross-sectional analysis of baseline data, including detailed information on dietary habits obtained as part of the overall life-style and risk factor assessment, as well as a complete vascular imaging study that was performed blinded to the clinical information. RESULTS: Most PESA participants follow a Mediterranean (40% of participants) or a Western (41%) dietary pattern. A new pattern, identified among 19% of participants, was labeled as a social-business eating pattern, characterized by a high consumption of red meat, pre-made foods, snacks, alcohol, and sugar-sweetened beverages and frequent eating-out behavior. Participants following this pattern presented a significantly worse cardiovascular risk profile and, after adjustment for risk factors, increased odds of presenting subclinical atherosclerosis (odds ratio: 1.31; 95% confidence interval: 1.06 to 1.63) compared with participants following a Mediterranean diet. CONCLUSIONS: A new social-business eating pattern, characterized by high consumption of red and processed meat, alcohol, and sugar-sweetened beverages, and by frequent snacking and eating out as part of an overall unhealthy life-style, is associated with an increased prevalence, burden, and multisite presence of subclinical atherosclerosis. (Progression of Early Subclinical Atherosclerosis [PESA]; NCT01410318)

    A 30-month worksite-based lifestyle program to promote cardiovascular health in middle-aged bank employees: Design of the TANSNIP-PESA randomized controlled trial

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    Cardiovascular disease (CVD) is the leading cause of death worldwide. With atherosclerosis as the underlying cause for many CVD events, prevention or reduction of subclinical atherosclerotic plaque burden (SAPB) through a healthier lifestyle may have substantial public health benefits. The objective was to describe the protocol of a randomized controlled trial investigating the effectiveness of a 30-month worksite-based lifestyle program aimed to promote cardiovascular health in participants having a high or a low degree of SAPB compared with standard care. We will conduct a randomized controlled trial including middle-aged bank employees from the Progression of Early Subclinical Atherosclerosis cohort, stratified by SAPB (high SAPB n = 260, low SAPB n = 590). Within each stratum, participants will be randomized 1:1 to receive a lifestyle program or standard care. The program consists of 3 elements: (a) 12 personalized lifestyle counseling sessions using Motivational Interviewing over a 30-month period, (b) a wrist-worn physical activity tracker, and (c) a sit-stand workstation. Primary outcome measure is a composite score of blood pressure, physical activity, sedentary time, body weight, diet, and smoking (ie, adapted Fuster-BEWAT score) measured at baseline and at 1-, 2-, and 3-year follow-up. The study will provide insights into the effectiveness of a 30-month worksite-based lifestyle program to promote cardiovascular health compared with standard care in participants with a high or low degree of SAPB.Sin financiación4.171 JCR (2017) Q2, 39/128 Cardiac and Cardiovascular SystemsUE

    Prevalence, Vascular Distribution, and Multiterritorial Extent of Subclinical Atherosclerosis in a Middle-Aged Cohort: The PESA (Progression of Early Subclinical Atherosclerosis) Study.

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    BACKGROUND: Data are limited on the presence, distribution, and extent of subclinical atherosclerosis in middle-aged populations. METHODS AND RESULTS: The PESA (Progression of Early Subclinical Atherosclerosis) study prospectively enrolled 4184 asymptomatic participants 40 to 54 years of age (mean age, 45.8 years; 63% male) to evaluate the systemic extent of atherosclerosis in the carotid, abdominal aortic, and iliofemoral territories by 2-/3-dimensional ultrasound and coronary artery calcification by computed tomography. The extent of subclinical atherosclerosis, defined as presence of plaque or coronary artery calcification ≥1, was classified as focal (1 site affected), intermediate (2-3 sites), or generalized (4-6 sites) after exploration of each vascular site (right/left carotids, aorta, right/left iliofemorals, and coronary arteries). Subclinical atherosclerosis was present in 63% of participants (71% of men, 48% of women). Intermediate and generalized atherosclerosis was identified in 41%. Plaques were most common in the iliofemorals (44%), followed by the carotids (31%) and aorta (25%), whereas coronary artery calcification was present in 18%. Among participants with low Framingham Heart Study (FHS) 10-year risk, subclinical disease was detected in 58%, with intermediate or generalized disease in 36%. When longer-term risk was assessed (30-year FHS), 83% of participants at high risk had atherosclerosis, with 66% classified as intermediate or generalized. CONCLUSIONS: Subclinical atherosclerosis was highly prevalent in this middle-aged cohort, with nearly half of the participants classified as having intermediate or generalized disease. Most participants at high FHS risk had subclinical disease; however, extensive atherosclerosis was also present in a substantial number of low-risk individuals, suggesting added value of imaging for diagnosis and prevention. CLINICAL TRIAL REGISTRATION: URL: http://www.clinicaltrials.gov. Unique identifier: NCT01410318

    Aplicación didáctica mediante virtualización de afloramientos geológicos por medio herramientas digitales de muy alta resolución

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    Tras la situación sanitaria del curso 2019-2020 y a través del Proyecto INNOVA Gestión 223 de la convocatoria del año 2020-2021, la Facultad de Ciencias Geológicas ha adquirido una herramienta para la virtualización de afloramientos geológicos. Durante el curso 2020-2021 se ha virtualizado una salida de campo de cada uno de los grados que se imparten en la Facultad, Grado en Geología y Grado en Ingeniería Geológica. Además, la mayor parte de la actividad de campo de este curso tendrá lugar durante el mes de mayo, por lo que los profesores van a poder realizar la virtualización de sus salidas de campo mientras realizan la salida presencial con los estudiantes, o incluso en algunas asignaturas los propios estudiantes van a ser los responsables de la virtualización de las mismas. Por ello, la herramienta GIGAPAN no sólo es de elevada utilidad en momentos en los que las restricciones de movilidad impiden la realización del campo sino que también permiten aplicar metodologías docentes invertidas durante la realización de los campamentos. De este modo los estudiantes pasan a tener un papel activo en relación a su proceso de aprendizaje. La herramienta GIGAPAN permite que se combinen imágenes fotográficas de megapíxeles de alta resolución para crear imágenes panorámicas de gigapíxeles que luego se pueden explorar a muchas escalas haciendo zoom y visión panorámica. Los GigaPans son gigapíxeles panorámicos, imágenes digitales con billones de píxeles. Gigapan crea panorámicas enormes, para conseguir elevado detalle con mucha nitidez. Además de proporcionar una experiencia de aprendizaje alternativa, estos recursos permiten una visita 'virtual' que puede ser una herramienta de aprendizaje útil en cualquier escenario docente. La utilidad del material generado tiene validez más allá de la pandemia, ya que puede ser utilizado por los estudiantes en el estudio de las asignaturas de la titulación, con un enorme potencial didáctico hasta ahora poco explorado. Hasta la fecha el GIGAPAN se ha venido utilizando con cámaras personales de profesores de la Facultad, por lo que se hace necesario completar esta herramienta con una cámara compatible con el módulo que permita ser usada tanto por profesores que no dispongan de la misma como por estudiantes de la Facultad
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