Mass Determination from Constraint Effective Potential

The Constraint Effective Potential (CEP) allows a determination of the mass and other quantities directly, without relying upon asymptotic correlator decays. We report and discuss the results of some mass calculations in $(\lambda \Phi^4)_4$, obtained from CEP and our improved version of CEP (ICEP).Comment: LATTICE99(Higgs, Yukawa, SUSY

Probing finite size effects in (λΦ4)4(\lambda \Phi^4)_4 MonteCarlo calculations

The Constrained Effective Potential (CEP) is known to be equivalent to the usual Effective Potential (EP) in the infinite volume limit. We have carried out MonteCarlo calculations based on the two different definitions to get informations on finite size effects. We also compared these calculations with those based on an Improved CEP (ICEP) which takes into account the finite size of the lattice. It turns out that ICEP actually reduces the finite size effects which are more visible near the vanishing of the external source.Comment: LATTICE98(Gauge, Higgs and Yukawa Models

The (λΦ4)4(\lambda \Phi^4)_4 theory on the lattice: effective potential and triviality

We compute numerically the effective potential for the $(\lambda \Phi^4)_4$ theory on the lattice. Three different methods were used to determine the critical bare mass for the chosen bare coupling value. Two different methods for obtaining the effective potential were used as a control on the results. We compare our numerical results with three theoretical descriptions. Our lattice data are in quite good agreement with the ``Triviality and Spontaneous Symmetry Breaking'' picture.Comment: Contribution to the Lattice '97 proceedings, LaTeX, uses espcrc2.sty, 3 page

Physical mechanisms generating spontaneous symmetry breaking and a hierarchy of scales

We discuss the phase transition in 3+1 dimensional lambda Phi^4 theory from a very physical perspective. The particles of the symmetric phase (`phions') interact via a hard-core repulsion and an induced, long-range -1/r^3 attraction. If the phion mass is sufficiently small, the lowest-energy state is not the `empty' state with no phions, but is a state with a non-zero density of phions Bose-Einstein condensed in the zero-momentum mode. The condensate corresponds to the spontaneous-symmetry-breaking vacuum with neq 0 and its excitations ("phonons" in atomic-physics language) correspond to Higgs particles. The phase transition happens when the phion's physical mass m is still positive; it does not wait until m^2 passes through zero and becomes negative. However, at and near the phase transition, m is much, much less than the Higgs mass M_h. This interesting physics coexists with `triviality;' all scattering amplitudes vanish in the continuum limit, but the vacuum condensate becomes infinitely dense. The ratio m/M_h, which goes to zero in the continuum limit, can be viewed as a measure of non-locality in the regularized theory. An intricate hierarchy of length scales naturally arises. We speculate about the possible implications of these ideas for gravity and inflation.Comment: 27 pages plus 2 files of figure

A lattice test of alternative interpretations of ``triviality'' in (λΦ4)4(\lambda \Phi^4)_4 theory

There are two physically different interpretations of ``triviality'' in $(\lambda\Phi^4)_4$ theories. The conventional description predicts a second-order phase transition and that the Higgs mass $m_h$ must vanish in the continuum limit if $v$, the physical v.e.v, is held fixed. An alternative interpretation, based on the effective potential obtained in ``triviality-compatible'' approximations (in which the shifted `Higgs' field $h(x)\equiv \Phi(x)-$ is governed by an effective quadratic Hamiltonian) predicts a phase transition that is very weakly first-order and that $m_h$ and $v$ are both finite, cutoff-independent quantities. To test these two alternatives, we have numerically computed the effective potential on the lattice. Three different methods were used to determine the critical bare mass for the chosen bare coupling value. All give excellent agreement with the literature value. Two different methods for obtaining the effective potential were used, as a control on the results. Our lattice data are fitted very well by the predictions of the unconventional picture, but poorly by the conventional picture.Comment: 16 pages, LaTeX, 2 eps figures (acknowledgements added in the replaced version

DAPK1 Promoter Methylation and Cervical Cancer Risk: A Systematic Review and a Meta-Analysis.

Objective: The Death-Associated Protein Kinase 1 (DAPK1) gene has been frequently investigated in cervical cancer (CC). The aim of the present study was to carry out a systematic review and a meta-analysis in order to evaluate DAPK1 promoter methylation as an epigenetic marker for CC risk. Methods A systematic literature search was carried out. The Cochrane software package Review Manager 5.2 was used. The fixed-effects or random-effects models, according to heterogeneity across studies, were used to calculate odds ratios (ORs) and 95% Confidence Intervals (CIs). Furthermore, subgroup analyses were conducted by histological type, assays used to evaluate DAPK1 promoter methylation, and control sample source. Results: A total of 20 papers, published between 2001 and 2014, on 1929 samples, were included in the meta-analysis. DAPK1 promoter methylation was associated with an increased CC risk based on the random effects model (OR: 21.20; 95%CI = 11.14–40.35). Omitting the most heterogeneous study, the between study heterogeneity decreased and the association increased (OR: 24.13; 95% CI = 15.83–36.78). The association was also confirmed in all the subgroups analyses. Conclusions: A significant strong association between DAPK1 promoter methylation and CC was shown and confirmed independently by histological tumor type, method used to evaluate methylation and source of control samples. Methylation markers may have value in early detection of CC precursor lesions, provide added reassurances of safety for women who are candidates for less frequent screens, and predict outcomes of women infected with human papilloma virus

First lattice evidence for a non-trivial renormalization of the Higgs condensate

General arguments related to ``triviality'' predict that, in the broken phase of $(\lambda\Phi^4)_4$ theory, the condensate re-scales by a factor $Z_{\phi}$ different from the conventional wavefunction-renormalization factor, $Z_{prop}$. Using a lattice simulation in the Ising limit we measure $Z_{\phi}=m^2 \chi$ from the physical mass and susceptibility and $Z_{prop}$ from the residue of the shifted-field propagator. We find that the two $Z$'s differ, with the difference increasing rapidly as the continuum limit is approached. Since $Z_{\phi}$ affects the relation of to the Fermi constant it can sizeably affect the present bounds on the Higgs mass.Comment: 10 pages, 3 figures, 1 table, Latex2