Granuloma annulare: report of 13 patients treated with photodynamic therapy

Dear Editor, Granuloma annulare (GA) is a benign in?ammatory granuloma- tous skin. Photodynamic therapy (PDT) has been described as another therapeutic option for localized GA, with a degree of recommendation B. Therefore, we have carried out a review of all patients with GA treated with PDT in our Dermatology Unit. We performed a retrospective observational study in San Jorge Hospital (Huesca, Spain) including all patients diagnosed with GA and treated with PDT between 2007 and 2018. Diagno- sis of GA was clinical and a skin biopsy was performed if it was necessary. In all patients, methyl aminolevulinate (MAL) or aminolevulinic acid (ALA) was applied under occlusive and opa- que dressing for 3 h and illuminated with LED 635 nm (Aktilite?, Uppsala, Sweden) with a ?uence of 37 J/cm . The lesions were prepared by a soft curettage or microneedling, and some lesions did not receive any kind of prior skin preparation. Continuous variables were described using means and standard deviations. Statistical analyses were carried out using SPSS soft- ware (version 20.0; IBM Corp, Armonk, NY, USA). Thirteen patients were included in the study (Table 1). Eleven cases (84.6%) were women and two men (15.4%), with a mean of 53 years old. Eighty-four per cent patients (n = 11) ..

Granuloma annulare: report of 13 patients treated with photodynamic therapy

Dear Editor, Granuloma annulare (GA) is a benign in?ammatory granuloma- tous skin. Photodynamic therapy (PDT) has been described as another therapeutic option for localized GA, with a degree of recommendation B. Therefore, we have carried out a review of all patients with GA treated with PDT in our Dermatology Unit. We performed a retrospective observational study in San Jorge Hospital (Huesca, Spain) including all patients diagnosed with GA and treated with PDT between 2007 and 2018. Diagno- sis of GA was clinical and a skin biopsy was performed if it was necessary. In all patients, methyl aminolevulinate (MAL) or aminolevulinic acid (ALA) was applied under occlusive and opa- que dressing for 3 h and illuminated with LED 635 nm (Aktilite?, Uppsala, Sweden) with a ?uence of 37 J/cm . The lesions were prepared by a soft curettage or microneedling, and some lesions did not receive any kind of prior skin preparation. Continuous variables were described using means and standard deviations. Statistical analyses were carried out using SPSS soft- ware (version 20.0; IBM Corp, Armonk, NY, USA). Thirteen patients were included in the study (Table 1). Eleven cases (84.6%) were women and two men (15.4%), with a mean of 53 years old. Eighty-four per cent patients (n = 11) ..