Bond Strength of Concrete Containing Different Recycled Coarse Aggregates

Some of the remnants of construction demolition wastes could be used after recycling as coarse aggregate in concrete industry. Among these wastes are ceramics, shale bricks and hardened concrete. This research was carried out to determine the effect of using such recycled aggregate (RA) as total or partial replacement of the natural dolomite coarse aggregate in concrete mixes on their compressive and bond strength with steel bars. Two types of concrete were investigated in this research which included normal concrete and self-compacted concrete. The main variables taken into consideration wee, the type of concrete, the type and percentage of the recycled aggregate and the age of testing. The consistency of the normal fresh concrete was measured by the slump test. However, the workability and flowability of the self-compacted fresh concrete were measured using slump test, V-funnel test. Out of the experimental test results, equations were predicted which correlated between the concrete compressive strength and bond strength of both the recycled aggregate ordinary concrete and the recycled aggregate self-compacted concrete. These equations were completely different than that of the steel-concrete bond equation of concrete with natural aggregate. Out of this research results, the recycled aggregate concrete could be used in both non structural applications and in some structural applications with special precautions

Feasibility of using self-compacting concrete in civil engineering applications

This research aimed to investigate the feasibility of using self-compacting concrete in civil engineering applications as a producing a precast hollow unit. The behavior of the hollow sections cast with self-compacted concrete beneath line-load was evaluated. An experimental work was carried out and a finite element model with ANSYS (version 15) was adopted. A total of fourteen hollow beams were cast and tested. The most variables taken into thought were; the types of reinforcement (reinforced steel bar and steel wire meshes), the types of steel wire meshes (expanded and welded steel wire mesh), number of layers of steel meshes (one layer and two layers), cross section thickness of concrete (40 mm and 60mm), concrete cover thickness (15mm and 20 mm) and also the shapes of cross section (square or circular). Special attention to initial cracking load, ultimate load, deflection, cracking pattern, energy absorption and ductility index were investigated. Good agreement was found compared with the experimental results. Out of this research; this paper presents applications of self-compacted concrete for casting skinny structural hollow members. These members can be used as precast units within the construction of the tunnel to decrease the problems in highway roads due to the difficulty of using crossing bridges particularly for kids and old people which are very useful for developing countries with great economic advantages

Protein Solubility, Digestibility and Fractionation after Germination of Sorghum Varieties

The changes in crude protein, free amino acids, amino acid composition, protein solubility, protein fractionation and protein digestibility after germination of sorghum were investigated. Sorghum varieties (Dorado, Shandaweel-6, Giza-15) were soaked for 20 h followed by germination for 72 h; the results revealed that crude protein and free amino acids in raw sorghum varieties ranged from 10.62 to 12.46% and 0.66 to 1.03 mg/g, respectively. Shandaweel-6 was the highest variety in crude protein and free amino acids content. After germination, crude protein was decreased and free amino acids were increased. There was an increase in content of valine and phenylalanine amino acids after germination. On the other hand, there was a decrease in most of amino acids after germination. After germination protein solubility was significantly increased. Regarding protein fractions, there was an increase in albumin, globulin and kafirin proteins and a decrease in cross linked kafirin and cross linked glutelin after germination

Effect of Soaking, Cooking, Germination and Fermentation Processing on Proximate Analysis and Mineral Content of Three White Sorghum Varieties (Sorghum bicolor L. Moench)

The changes in chemical composition, amylose and minerals content after soaking, cooking, germination and fermentation of three white sorghum varieties, named ‘Dorado’, ‘Shandaweel-6’, and ‘Giza-15’ were investigated. The chemical composition concluded including crude protein, oils, crude fiber and ash. Crude protein content ranged from 10.62 to 12.46% in raw sorghum. ‘Shandaweel-6’ was the highest variety in crude protein content (12.46%). ‘Dorado’ was the highest variety in oils and ash (3.91 and 1.45%). ‘Shandaweel-6’ was the highest variety in crude fiber (1.85%). Amylose content ranged from 18.30 to 20.18% in raw sorghum. Amylose was higher in ‘Giza-15’ than other varieties. Minerals content i.e., Zn, Fe, Ca, K, Na, Mg, Mn and Cu were investigated. Results indicated that raw ‘Dorado’ was the highest variety in K, Mg, Ca, Fe and Mn (264.53, 137.14, 33.09, 7.65 and 1.98 mg/100 g). While, ‘Shandaweel-6’ was the highest variety in Zn and Cu (5.02 and 0.84 mg/100 g). Finally ‘Giza-15’ was the highest variety in P and Na (381.37 and 119.29 mg/100 g). After treatments chemical composition, amylose and minerals were decreased. Processing techniques reduce the levels of antinutritional organic factors, which including phytates, phenols, tannins and enzyme inhibitors by releasing exogenous and endogenous enzymes such as phytase enzyme formed during processing

Ethnicity, consanguinity, and genetic architecture of hypertrophic cardiomyopathy

AIMS: Hypertrophic cardiomyopathy (HCM) is characterized by phenotypic heterogeneity that is partly explained by the diversity of genetic variants contributing to disease. Accurate interpretation of these variants constitutes a major challenge for diagnosis and implementing precision medicine, especially in understudied populations. The aim is to define the genetic architecture of HCM in North African cohorts with high consanguinity using ancestry-matched cases and controls. METHODS AND RESULTS: Prospective Egyptian patients (n = 514) and controls (n = 400) underwent clinical phenotyping and genetic testing. Rare variants in 13 validated HCM genes were classified according to standard clinical guidelines and compared with a prospective HCM cohort of majority European ancestry (n = 684). A higher prevalence of homozygous variants was observed in Egyptian patients (4.1% vs. 0.1%, P = 2 × 10-7), with variants in the minor HCM genes MYL2, MYL3, and CSRP3 more likely to present in homozygosity than the major genes, suggesting these variants are less penetrant in heterozygosity. Biallelic variants in the recessive HCM gene TRIM63 were detected in 2.1% of patients (five-fold greater than European patients), highlighting the importance of recessive inheritance in consanguineous populations. Finally, rare variants in Egyptian HCM patients were less likely to be classified as (likely) pathogenic compared with Europeans (40.8% vs. 61.6%, P = 1.6 × 10-5) due to the underrepresentation of Middle Eastern populations in current reference resources. This proportion increased to 53.3% after incorporating methods that leverage new ancestry-matched controls presented here. CONCLUSION: Studying consanguineous populations reveals novel insights with relevance to genetic testing and our understanding of the genetic architecture of HCM

Three-dimensional verification of volumetric measurements and relationships between the condyle and the rest of the mandible; a novel approach

Background: Few studies have investigated the volumetric relationship between the condyles and the mandible bilaterally.Materials and methods: Condylar and mandibular segmentations from a sample of cone-beam computed tomography for 37 individuals were selected. T-test, correlation and linear regression analyses were performed to assess the relationships between the volumes of the condyles and mandible.Results: The volume of the condyles and the mandible was significantly different between genders (p < 0.05). There was a significant but moderate correlation between the volumes of the condyle and the rest of the mandible on the same side (p < 0.01). A regression analysis model demonstrated that condylar volume is related to the volume of the mandible.Conclusions: The relationship between the condylar volume and the rest of the mandible was found to be moderate. The relation between the condylar volume and mandibular volume is described by the regression equations for each side of the jaw. Sexual dimorphism exists in condylar and mandibular volumes

Relation between microRNAs and Apoptosis in Hepatocellular Carcinoma

AIM: To determine the relation between serum microRNAs and apoptotic markers as regards development of HCC to understand the underlying mechanism of HCV related hepatocarcinogenesis. PATIENTS AND METHODS: A total of 65 serum samples (25 samples from controls, 20 samples from hepatitis and 20 samples from HCC patients) were collected for miRNAs (mir 21, mir 199-a, and mir 155) detection. Human Programmed cell death protein-4 (PDCD-4) and Human Cytochrome-C (CYT-C) were determined. RESULTS: miRNAs 21 and 155 were over expressed in sera of patients with HCC compared to patients with chronic hepatitis (p < 0.0001). While serum means values of miR 199a was significantly decreased among HCC group patients when compared to patients with chronic hepatitis (p < 0.0001). The serum levels of PCDC4 and CYTC were increased in patients with HCC when compared to chronic hepatitis patients. They were also increased in patients with chronic hepatitis when compared to controls (p < 0.05, significant). There was direct correlations between apoptotic markers and oncomirs miRNAs 21 and 155 while apoptotic markers were inversely correlated with miRNA 199-a. CONCLUSION: Both microRNAs and apoptotic markers have roles in HCC pathogenesis. It seems that oncogenic microRNAs induce liver carcinogenesis in HCV patients irrespective of suppression of apoptosis.AIM: To determine the relation between serum microRNAs and apoptotic markers as regards development of HCC to understand the underlying mechanism of HCV related hepatocarcinogenesis. PATIENTS AND METHODS: A total of 65 serum samples (25 samples from controls, 20 samples from hepatitis and 20 samples from HCC patients) were collected for miRNAs (mir 21, mir 199-a, and mir 155) detection. Human Programmed cell death protein-4 (PDCD-4) and Human Cytochrome-C (CYT-C) were determined. RESULTS: miRNAs 21 and 155 were over expressed in sera of patients with HCC compared to patients with chronic hepatitis (p < 0.0001). While serum means values of miR 199a was significantly decreased among HCC group patients when compared to patients with chronic hepatitis (p < 0.0001). The serum levels of PCDC4 and CYTC were increased in patients with HCC when compared to chronic hepatitis patients. They were also increased in patients with chronic hepatitis when compared to controls (p < 0.05, significant). There was direct correlations between apoptotic markers and oncomirs miRNAs 21 and 155 while apoptotic markers were inversely correlated with miRNA 199-a. CONCLUSION: Both microRNAs and apoptotic markers have roles in HCC pathogenesis. It seems that oncogenic microRNAs induce liver carcinogenesis in HCV patients irrespective of suppression of apoptosis

The Effect of Hotel Employees’ Emotional Labour on Interpersonal Counterproductive Work Behaviours

This research aims to shed light on the effect of hotels’ employees' emotional labour with its three levels (surface acting, deep acting and genuine emotions) on interpersonal counterproductive work behaviours. To achieve this aim, a questionnaire was designed for Egyptian hotels’ employees which was structured to cover three main parts: (1) demographic characteristics of employees, (2) employees' emotional labour and (3) interpersonal counterproductive work behaviours. Structural equation modelling (SEM) was used involving (smart- PLS) software, IBM, version 4. The results show that the hotels’ employees' emotional labour with its three levels (surface acting, deep acting and genuine emotions) affects interpersonal counterproductive work behaviours with its two types (task focused and person focused) as there is a positive effect of surface acting on interpersonal counterproductive work behaviour. Employees' emotional labour must be seriously handled within the hospitality industry as it is a very important element affecting task-focused or person-focused ICWBs in the hotel. As both surface acting and genuine emotions increase task-focused or person-focused ICWBs, deep acting decreases task-focused or person-focused ICWBs