Implementation of intensity modulated radiotherapy for prostate cancer in a private radiotherapy service in Mexico

Intensity modulated radiation therapy (IMRT) allows physicians to deliver higher conformal doses to the tumour, while avoiding adjacent structures. As a result the probability of tumour control is higher and toxicity may be reduced. However, implementation of IMRT is highly complex and requires a rigorous quality assurance (QA) program both before and during treatment. The present article describes the process of implementing IMRT for localized prostate cancer in a radiation therapy department. In our experience, IMRT implementation requires careful planning due to the need to simultaneously implement specialized software, multifaceted QA programs, and training of the multidisciplinary team. Establishing standardized protocols and ensuring close collaboration between a multidisciplinary team is challenging but essential

A Single Cutaneous Metastasis In A Male With Breast Cancer Treated With Surgery And Adjuvant Radiotherapy: A Case Report

Background: Breast cancer in men is a rare disease that represents <1% of cases. Currently, there is no consensus on the management of this disease in men and even less in distant recurrences, the information that is available is extracted from the management in women and from retrospective studies. Case report: We present the case of a man with breast cancer stage IIA (T1, N1, M0) AJCC 2010 treated with modified radical mastectomy, adjuvant chemotherapy and radiotherapy, which during the follow-up presented a nodular lesion on the face with positive histopathologic report for a metastasis from a breast adenocarcinoma then he was treated aggressively with surgery and radiotherapy to the tumor bed with adequate local control and survival of the disease. Conclusion: Breast cancer in men represents <1% of the cases. there are a few reports of patients with a few metastatic lesions to the skin from breast cancer and most of these report mention that there is no consensus in the management of these patients given its low incidence and the treatment should be individualized according to each scenario

Phase Angle and Nutritional Status: The Impact on Survival and Health-Related Quality of Life in Locally Advanced Uterine Cervical Cancer

The phase angle, an indicator of muscle mass status and membrane cell integrity, has been associated with low survival, poorer clinical outcomes, and worse quality of life among cancer patients, but information on women with uterine cervical cancer (UCCa) is scarce. In this prospective study, we used a bioelectrical impedance analyzer to obtain the PA of 65 women with UCCa. We compared the health-related quality of life and inflammatory and nutritional indicators between low PA and normal PA. The mean age was 52 ± 13. The low PA and normal PA groups differed in terms of the C-reactive protein (15.8 ± 19.6 versus 6.82 ± 5.02, p = 0.022), glucose (125.39 ± 88.19 versus 88.78 ± 23.08, p = 0.021), albumin (3.9 ± 0.39 versus 4.37 ± 0.30, p = 0.000), EORTC QLQ-C30 loss of appetite symptom scale score (33.33 (0.0–100.00) versus 0.0 (0.0–0.0), p = 0.005), and EORTC QLQ-CX24 menopausal symptoms scale score (0.0 (0.0–33.33) versus 0.0 (0.0–100.0), p = 0.03). The main finding of the present study is the interaction between PA and obesity as critical cofactors in the UCCa adeno and adenosquamous histologic variants, to a greater extent than cervical squamous cell carcinoma