2 research outputs found
Evaluation of plasma lipids and lipoproteins in nigerians suffering from depressive illness
There are conflicting reports on the role of plasma lipids in
depressive illness. Very little is known about the lipid and
lipoprotein status in Nigerian adults suffering from depression. One
hundred subjects consisting of sixty (60) depressed patients with mean
age (40.3±12.3 yrs) and forty (40) apparently healthy controls
(40.1±10.1 yrs) were selected for the study. All subjects were
free from medication at least one month prior to the start of the
experiment. The anthropometric indices were also determined. There was
a significant increase in plasma triglyceride concentration in
depressed subjects when compared to control values (p<0.01).
However, the plasma total cholesterol, low density lipoprotein
cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) and
body mass index (BMI) did not significantly differ from control values.
The mean plasma triglyceride was significantly increased in female
patients in comparison to corresponding female controls. Plasma lipid
and lipoprotein levels did not demonstrate any definite pattern with
increasing level of depression in patients. In conclusion, plasma lipid
levels could play a significant role in depressive illness in Nigerian
Evaluation of Plasma Lipids and Lipoproteins in Nigerians Suffering From Depressive Illness
There are conflicting reports on the role of plasma lipids in
depressive illness. Very little is known about the lipid and
lipoprotein status in Nigerian adults suffering from depression. One
hundred subjects consisting of sixty (60) depressed patients with mean
age (40.3±12.3 yrs) and forty (40) apparently healthy controls
(40.1±10.1 yrs) were selected for the study. All subjects were
free from medication at least one month prior to the start of the
experiment. The anthropometric indices were also determined. There was
a significant increase in plasma triglyceride concentration in
depressed subjects when compared to control values (p<0.01).
However, the plasma total cholesterol, low density lipoprotein
cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C) and
body mass index (BMI) did not significantly differ from control values.
The mean plasma triglyceride was significantly increased in female
patients in comparison to corresponding female controls. Plasma lipid
and lipoprotein levels did not demonstrate any definite pattern with
increasing level of depression in patients. In conclusion, plasma lipid
levels could play a significant role in depressive illness in Nigerian