122 research outputs found
Oesophageal Foreign Bodies: An Experience with Rigid Oesophagoscopy in a Developing Country
No Abstract
Assessment of the water quality parameters in relation to fish community of Osinmo reservoir, Ejigbo, Osun State, Nigeria
Physicochemical indices of water body changed seasonally and this necessitated an investigation to assess the water quality parameters of Osinmo reservoir in relation to its fish species. The water quality parameters were measured using standard methods. Results obtained show that the reservoir is alkaline in nature with dissolved oxygen concentration (1.8-7.2 mgl-1) and alkalinity (64 CaCO3 mgl-1-108 CaCO3 mgl-1) which were within the optimum range for growth and survival of fish. Four families of fish comprising eight species were encountered. The sex-ratio of five species which were statistically different (P<0.05) indicatedreproductive efficiency populations while other fish species whose sex-ratio differed insignificantly (P>0.05) revealed a growing population. The well-being of the fish species was adequate as observed in the least meancondition factor of 0.666±0.057 in C. gariepinus and the highest mean of 2.000±0.242 in S. galilaeus. The productivity of the reservoir can be improved through proper management of the water body.Keywords: Water quality, fish abundance, diversity, fish biometrics, sex-ratio, condition factor
Sustaining Carbon Sink Potentials in Tropical Forest
Forests are major carbon sinks and providers of environmental services which are currently not paid for. Despite the increasing awareness in recent years of the unique and crucial role that forests play in climate stabilization, not to mention their capacity to protect water, soil, and biodiversity, deforestation continues at an alarming rate. Deforestation is by far the leading contributor to greenhouse gas emissions in developing countries.Reducing carbon emissions from deforestation and degradation in developing countries is of central importance in efforts to combat climate change. In order to solve the climate change problem, there is need to reduce atmospheric concentration of green gases to a safe level.This paper examines the measures of sustaining carbon sink potentials in tropical forest
Effect of Plant Spacing in the Nursery on the Production of Planting Materials for Field Establishment of Vetiver Grass
A study was conducted between June and October, 2001, at the Teaching and Research Farm of the University of Ibadan (7° 24' N, 3° 54' E), Nigeria, to evaluate the effect of plant spacing in the nursery on the growth of vetiver grass (Vetiveria zizanioides L.) so as to determine the optimum plant spacing in the nursery for the production of planting materials for field establishment. Four spacings, 20 x 30 cm2, 15 x 40 cm2, 20 x 40 cm2 and 40 x 40 cm2, were replicated four times and laid out in a randomized complete block design. Treatment plots measured 4 m x 4 m. Per stand, two vetiver tillers were planted on flat seedbeds. Parameters assessed included plant height, dry matter yield and tiller production. Shoot, root and total plant dry matter and tiller count were measured at 16 weeks after planting (WAP). Spacing had no effect (P< 0.05) on plant height but impacted very significantly (P< 0.01) on root, shoot and total plant dry matter production, which increased with wider spacing. In a spatial context, dry matter yield per hectare was least in the widest spacing. Spacing had no effect (P< 0.05) on number of tillers produced per planted tiller (multiplication rate) but it had a very significant effect (P< 0.01) on the number of tillers produced per unit area. The closest spacings, 20 x 30 cm2 and 15 x 40 cm2, which gave the highest number of tillers per hectare (203.3 x 104 and 196.7 x 104, respectively), were recommended for production of planting materials in the nursery
The micro-minerals composition in serum of rabbits (Oryctolagus cuniculus) infected with Trypanosoma congolense
Sixteen (16) rabbits aged between 6 to 12 months were infected with fresh stock of Trypanosoma congolense (Gboko strain) intravenously at the rate of 1.0 × 106ml. Animals were classified into two groups; groups A were infected, while group B served as uninfected controls. Samples from the infected and the uninfected controls showed a significant increase in the levels of sodium (Na+), calcium (Ca2+), phosphate (PO4 2-) and blood urea nitrogen (BUN) (P < 0.05) and a significant decline in the levels of potassium (K+) and bicarbonate (HCO3 2-) (P < 0.05). Therefore, the alterations in the compositions of these micro-minerals in the serum of rabbits may suggest that, they could have a role in the pathogenesis of trypanosomosis due to T. congolense infection.Key words: Rabbits, micro-minerals, Trypanosoma congolense, pathogenesis
The role of laboratory confirmations and molecular epidemiology in global eradication of measles
This review reports on the role of laboratory confirmation and molecular epidemiology in global eradication of measles. The role of laboratory confirmation and molecular epidemiology in defining the origins of measles outbreaks cannot be overemphasized. New serological tests based on recombinant proteins detect only a fraction of the total measles virus (MV) specific antibodies. Several assays based on recombinant MV-haemagglutinin (ELISA and flow cytometry) or MV-fusion protein (flow cytometry) as well as neutralization and haemagglutination test have been evaluated using a large panel of lowtitre and negative sera. Isolation of measles virus confirmed the diagnosis. Phylogenetic trees are invaluable tools for monitoring the progress of immunization activities. Recent advances in genomic sequencing technology have lent its support to the monitoring and evaluation of vaccination programmes. More so, indigenous prepared measles antigens has been advocated to be produced, refined further and reproduced massively. This will be highly cost effective especially in field for seromonitoring and surveillance of measles. There is therefore, continual need for simpler diagnostic tests in elimination and eventual eradication of measles
In vitro Anticancer Screening of 24 Locally Used Nigerian Medicinal Plants
Background: Plants that are used as traditional medicine represent a relevant pool for selecting plant candidates that may have anticancer properties. In this study, the ethnomedicinal approach was used to select several medicinal plants native to Nigeria, on the basis of their local or traditional uses. The collected plants were then evaluated for cytoxicity. Methods: The antitumor activity of methanolic extracts obtained from 24 of the selected plants, were evaluated in vitro on five human cancer cell lines. Results: Results obtained from the plants screened indicate that 18 plant extracts of folk medicine exhibited promising cytotoxic activity against human carcinoma cell lines. Erythrophleum suaveolens (Guill. & Perr.) Brenan was found to demonstrate potent anti-cancer activity in this study exhibiting IC50 = 0.2-1.3 g/ml. Conclusions: Based on the significantly potent activity of some plants extracts reported here, further studies aimed at mechanism elucidation and bio-guided isolation of active anticancer compounds is currently underway.Chemistry and Chemical Biolog
Effect of Microwave Frying on Acrylamide Generation, Mass Transfer, Color, and Texture in French Fries
[EN] The objective of this work was to evaluate the effect of microwave power on acrylamide generation, as well as moisture and oil fluxes and quality attributes of microwave-fried potatoes. Concretely, 25 g of potato strips, in 250 mL of fresh oil (at room temperature), were subjected to three different microwave powers (315, 430, and 600 W) in a conventional microwave oven. Microwave frying resulted in an acrylamide reduction ranged from 37 to 83% compared to deep-oil frying. Microwave-fried French fries presented lower moisture and higher fat content than deep-oil fried potatoes. Concretely, microwave-fried potatoes presented values of moisture and texture more similar to potato chips than French fries, nonetheless with lower fat levels (less than 20 g/100 g wb) and acrylamide content (lower than 100 ¿g/kg wb) at the reference time. This study presents an alternative way of frying to address the production of healthier potato chips.The authors would like to thank the Universitat Politecnica de Valencia for the PhD scholarship given to Mariola Sansano Tomas.Sansano, M.; De Los Reyes Cánovas, R.; Andrés Grau, AM.; Heredia Gutiérrez, AB. (2018). Effect of Microwave Frying on Acrylamide Generation, Mass Transfer, Color, and Texture in French Fries. Food and Bioprocess Technology. 11(10):1934-1939. doi:10.1007/s11947-018-2144-zS193419391110AACC. (1995). Approved methods of the American association of cereal chemists (9th ed.). St. Paul: The Association.Adedeji, A. A., Ngadi, M. O., & Raghavan, G. S. V. (2009). Kinetics of mass transfer in microwave precooked and deep-fat fried chicken nuggets. Journal of Food Engineering, 91(1), 146–153.Ahrné, L., Andersson, C.-G., Floberg, P., Rosén, J., & Lingnert, H. (2007). 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Echocardiographic partition values and prevalence of left ventricular hypertrophy in hypertensive Nigerians
BACKGROUND: Left ventricular hypertrophy (LVH) is a well known independent risk factor for cardiovascular events. It has been shown that combination of left ventricular mass (LVM) and relative wall thickness (RWT) can be used to identify different forms of left ventricular (LV) geometry. Prospective studies have shown that LV geometric patterns have prognostic implications, with the worst prognosis associated with concentric hypertrophy. The methods for the normalization or indexation of LVM have also recently been shown to confer some prognostic value especially in obese population. We sought to determine the prevalence of echocardiographic lLVH using eight different and published cut-off or threshold values in hypertensive subjects seen in a developing country's tertiary centre. METHODS: Echocardiography was performed in four hundred and eighty consecutive hypertensive subjects attending the cardiology clinic of the University college Hospital Ibadan, Nigeria over a two-year period. RESULTS: Complete data was obtained in 457 (95.2%) of the 480 subjects (48.6% women). The prevalence of LVH ranged between 30.9–56.0%. The highest prevalence was when LVM was indexed to the power of 2.7 with a partition value of 49.2 g/ht(2.7 )in men and 46.7 g/ht(2.7 )in women. The lowest prevalence was observed when LVM was indexed to body surface area (BSA) and a partition value of 125 g/m(2 )was used for both sexes. Abnormal LV geometry was present in 61.1%–74.0% of our subjects and commoner in women. CONCLUSION: The prevalence of LVH hypertensive patients is strongly dependent on the cut-off value used to define it. Large-scale prospective study will be needed to determine the prognostic implications of the different LV geometry in native Africans
Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015
SummaryBackground The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 provides an up-to-date synthesis of the evidence for risk factor exposure and the attributable burden of disease. By providing national and subnational assessments spanning the past 25 years, this study can inform debates on the importance of addressing risks in context. Methods We used the comparative risk assessment framework developed for previous iterations of the Global Burden of Disease Study to estimate attributable deaths, disability-adjusted life-years (DALYs), and trends in exposure by age group, sex, year, and geography for 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks from 1990 to 2015. This study included 388 risk-outcome pairs that met World Cancer Research Fund-defined criteria for convincing or probable evidence. We extracted relative risk and exposure estimates from randomised controlled trials, cohorts, pooled cohorts, household surveys, census data, satellite data, and other sources. We used statistical models to pool data, adjust for bias, and incorporate covariates. We developed a metric that allows comparisons of exposure across risk factors—the summary exposure value. Using the counterfactual scenario of theoretical minimum risk level, we estimated the portion of deaths and DALYs that could be attributed to a given risk. We decomposed trends in attributable burden into contributions from population growth, population age structure, risk exposure, and risk-deleted cause-specific DALY rates. We characterised risk exposure in relation to a Socio-demographic Index (SDI). Findings Between 1990 and 2015, global exposure to unsafe sanitation, household air pollution, childhood underweight, childhood stunting, and smoking each decreased by more than 25%. Global exposure for several occupational risks, high body-mass index (BMI), and drug use increased by more than 25% over the same period. All risks jointly evaluated in 2015 accounted for 57·8% (95% CI 56·6–58·8) of global deaths and 41·2% (39·8–42·8) of DALYs. In 2015, the ten largest contributors to global DALYs among Level 3 risks were high systolic blood pressure (211·8 million [192·7 million to 231·1 million] global DALYs), smoking (148·6 million [134·2 million to 163·1 million]), high fasting plasma glucose (143·1 million [125·1 million to 163·5 million]), high BMI (120·1 million [83·8 million to 158·4 million]), childhood undernutrition (113·3 million [103·9 million to 123·4 million]), ambient particulate matter (103·1 million [90·8 million to 115·1 million]), high total cholesterol (88·7 million [74·6 million to 105·7 million]), household air pollution (85·6 million [66·7 million to 106·1 million]), alcohol use (85·0 million [77·2 million to 93·0 million]), and diets high in sodium (83·0 million [49·3 million to 127·5 million]). From 1990 to 2015, attributable DALYs declined for micronutrient deficiencies, childhood undernutrition, unsafe sanitation and water, and household air pollution; reductions in risk-deleted DALY rates rather than reductions in exposure drove these declines. Rising exposure contributed to notable increases in attributable DALYs from high BMI, high fasting plasma glucose, occupational carcinogens, and drug use. Environmental risks and childhood undernutrition declined steadily with SDI; low physical activity, high BMI, and high fasting plasma glucose increased with SDI. In 119 countries, metabolic risks, such as high BMI and fasting plasma glucose, contributed the most attributable DALYs in 2015. Regionally, smoking still ranked among the leading five risk factors for attributable DALYs in 109 countries; childhood underweight and unsafe sex remained primary drivers of early death and disability in much of sub-Saharan Africa. Interpretation Declines in some key environmental risks have contributed to declines in critical infectious diseases. Some risks appear to be invariant to SDI. Increasing risks, including high BMI, high fasting plasma glucose, drug use, and some occupational exposures, contribute to rising burden from some conditions, but also provide opportunities for intervention. Some highly preventable risks, such as smoking, remain major causes of attributable DALYs, even as exposure is declining. Public policy makers need to pay attention to the risks that are increasingly major contributors to global burden. Funding Bill & Melinda Gates Foundation
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