Values of Exemplary Jesuit College Graduates

What values do undergraduates adopt and internalize as a result of their college experiences at a Catholic Jesuit college/university? In an attempt to answer this question, the authors chose 21 exemplary graduates from 2000-2007 at a Catholic, Jesuit college in the northeastern part of the United States and conducted a ten question intensive interview with each of them. After transcribing and coding the interviews, it was discovered that these graduates had a strong grasp of such Jesuit ideals as “men and women for others,” “educating the whole person,” “cura personalis,” and “magis,” but apparently a weaker grasp of the more recent Jesuit emphasis on diversity and social justice. Faculty and members of the campus ministry staff had a strong influence on helping these graduates to develop a better sense of Jesuit values. Campus ministry activities, service and immersion trips, and research with faculty helped those interviewed to learn and practice Jesuit values

Cardiolipin interactions with proteins

Cardiolipins (CL) represent unique phospholipids of bacteria and eukaryotic mitochondria with four acyl chains and two phosphate groups that have been implicated in numerous functions from energy metabolism to apoptosis. Many proteins are known to interact with CL, and several cocrystal structures of protein-CL complexes exist. In this work, we describe the collection of the first systematic and, to the best of our knowledge, the comprehensive gold standard data set of all known CL-binding proteins. There are 62 proteins in this data set, 21 of which have nonredundant crystal structures with bound CL molecules available. Using binding patch analysis of amino acid frequencies, secondary structures and loop supersecondary structures considering phosphate and acyl chain binding regions together and separately, we gained a detailed understanding of the general structural and dynamic features involved in CL binding to proteins. Exhaustive docking of CL to all known structures of proteins experimentally shown to interact with CL demonstrated the validity of the docking approach, and provides a rich source of information for experimentalists who may wish to validate predictions