1,037 research outputs found
Symmetries of generalized soliton models and submodels on target space
Some physically relevant non-linear models with solitons, which have target
space , are known to have submodels with infinitly many conservation laws
defined by the eikonal equation. Here we calculate all the symmetries of these
models and their submodels by the prolongation method. We find that for some
models, like the Baby Skyrme model, the submodels have additional symmetries,
whereas for others, like the Faddeev--Niemi model, they do not.Comment: 18 pages, one Latex fil
A Smirnov-Bickel-Rosenblatt theorem for compactly-supported wavelets
In nonparametric statistical problems, we wish to find an estimator of an
unknown function f. We can split its error into bias and variance terms;
Smirnov, Bickel and Rosenblatt have shown that, for a histogram or kernel
estimate, the supremum norm of the variance term is asymptotically distributed
as a Gumbel random variable. In the following, we prove a version of this
result for estimators using compactly-supported wavelets, a popular tool in
nonparametric statistics. Our result relies on an assumption on the nature of
the wavelet, which must be verified by provably-good numerical approximations.
We verify our assumption for Daubechies wavelets and symlets, with N = 6, ...,
20 vanishing moments; larger values of N, and other wavelet bases, are easily
checked, and we conjecture that our assumption holds also in those cases
NMR and TRLFS studies of Ln(III) and An(III) C5-BPP complexes
C5-BPP is a highly efficient N-donor ligand for the separation of trivalent actinides, An(III), from trivalent lanthanides, Ln(III). The molecular origin of the selectivity of C5-BPP and many other N-donor ligands of the BTP-type is still not entirely understood. We present here the first NMR studies on C5-BPP Ln(III) and An(III) complexes. C5-BPP is synthesized with 10% 15N labeling and characterized by NMR and LIFDI-MS methods. 15N NMR spectroscopy gives a detailed insight into the bonding of C5-BPP with lanthanides and Am(III) as a representative for trivalent actinide cations, revealing significant differences in 15N chemical shift for coordinating nitrogen atoms compared to Ln(III) complexes. The temperature dependence of NMR chemical shifts observed for the Am(III) complex indicates a weak paramagnetism. This as well as the observed large chemical shift for coordinating nitrogen atoms show that metal–ligand bonding in Am(C5-BPP)3 has a larger share of covalence than in lanthanide complexes, confirming earlier studies. The Am(C5-BPP)3 NMR sample is furthermore spiked with Cm(III) and characterized by time-resolved laser fluorescence spectroscopy (TRLFS), yielding important information on the speciation of trace amounts of minor complex species
Impact of a quadrivalent meningococcal ACWY glycoconjugate or a serogroup B meningococcal vaccine on meningococcal carriage: an observer-blind, phase 3 randomised clinical trial
Background: Meningococcal conjugate vaccines protect individuals directly, but also confer herd protection by interrupting carriage transmission. This Phase III observer-blind, randomised, controlled study evaluated the effects of meningococcal quadrivalent (ACWY) glycoconjugate (MenACWY-CRM) or serogroup B (4CMenB) vaccination on meningococcal carriage rates in young adults.
Methods: University students (aged 18–24 years) from ten sites in England were randomised to receive two vaccinations one month apart: two doses of Japanese Encephalitis vaccine (controls), two doses of 4CMenB (4CMenB), or one dose of MenACWY-CRM then placebo (MenACWY-CRM). Meningococci were isolated from oropharyngeal swabs collected before vaccination and at five scheduled intervals over one year. Primary analysis was cross-sectional carriage one month after the vaccine course; secondary analyses included comparison of carriage at any time point after primary analysis until study termination.
Findings: 2954 subjects were randomised (control, n=987; 4CMenB, n=988; MenACWY-CRM, n=979); approximately one-third of each group was positive for meningococcal carriage at study entry. By one month, there was no significant difference in carriage between controls and 4CMenB (Odds Ratios (OR) [95% CI]; 1·2 [0·8−1·7]) or MenACWY-CRM (OR [95% CI], 0·9 [0·6–1·3]) groups. From three months after dose two, 4CMenB vaccination resulted in significantly lower carriage of any meningococcal strain (calculated efficacy 18·2% [95% CI: 3·4–30·8]) and capsular groups BCWY (calculated efficacy 26·6% [95% CI: 10·5–39·9]) compared to control vaccination. Significantly lower carriage rates were also observed in the MenACWY-CRM group compared with controls: calculated efficacies 39·0% [95%CI: 17·3-55·0] and 36.2% [95%CI: 15·6-51·7] for serogroups Y and CWY, respectively.
Interpretation: MenACWY-CRM and 4CMenB vaccines reduced meningococcal carriage rates over 12 months post-vaccination and, therefore, may affect transmission where widely implemented
Structured light enhanced machine learning for fiber bend sensing
The intricate optical distortions that occur when light interacts with complex media, such as few- or multi-mode optical fiber, often appear random in origin and are a fundamental source of error for communication and sensing systems. We propose the use of orbital angular momentum (OAM) feature extraction to mitigate phase-noise and allow for the use of intermodal-coupling as an effective tool for fiber sensing. OAM feature extraction is achieved by passive all-optical OAM demultiplexing, and we demonstrate fiber bend tracking with 94.1% accuracy. Conversely, an accuracy of only 14% was achieved for determining the same bend positions when using a convolutional-neural-network trained with intensity measurements of the output of the fiber. Further, OAM feature extraction used 120 times less information for training compared to intensity image based measurements. This work indicates that structured light enhanced machine learning could be used in a wide range of future sensing technologies
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