115 research outputs found
Applications of the Mellin-Barnes integral representation
We apply the Mellin-Barnes integral representation to several situations of
interest in mathematical-physics. At the purely mathematical level, we derive
useful asymptotic expansions of different zeta-functions and partition
functions. These results are then employed in different topics of quantum field
theory, which include the high-temperature expansion of the free energy of a
scalar field in ultrastatic curved spacetime, the asymptotics of the -brane
density of states, and an explicit approach to the asymptotics of the
determinants that appear in string theory.Comment: 20 pages, LaTe
Immunopathology of Postprimary Tuberculosis: Increased T-Regulatory Cells and DEC-205-Positive Foamy Macrophages in Cavitary Lesions
Postprimary tuberculosis occurs in immunocompetent people infected with Mycobacterium tuberculosis. It is restricted to the lung and accounts for 80% of cases and nearly 100% of transmission. Little is known about the immunopathology of postprimary tuberculosis due to limited availability of specimens. Tissues from 30 autopsy cases of pulmonary tuberculosis were located. Sections of characteristic lesions of caseating granulomas, lipid pneumonia, and cavitary stages of postprimary disease were selected for immunohistochemical studies of macrophages, lymphocytes, endothelial cells, and mycobacterial antigens. A higher percentage of cells in lipid pneumonia (36.1%) and cavitary lesions (27.8%) were positive for the dendritic cell marker DEC-205, compared to granulomas (9.0%, P < .05). Cavities contained significantly more T-regulatory cells (14.8%) than found in lipid pneumonia (5.2%) or granulomas (4.8%). Distribution of the immune cell types may contribute to the inability of the immune system to eradicate tuberculosis
Lactoferrin Augmentation of the BCG Vaccine Leads to Increased Pulmonary Integrity
The goal of vaccination to prevent tuberculosis disease (TB) is to offer long-term protection to the individual and the community. In addition, the success of any protective TB vaccine should include the ability to limit cavitary formation and disease progression. The current BCG vaccine protects against disseminated TB disease in children by promoting development of antigenic-specific responses. However, its efficacy is limited in preventing postprimary pulmonary disease in adults that is responsible for the majority of disease and transmission. This paper illustrates the use of lactoferrin as an adjuvant to boost efficacy of the BCG vaccine to control organism growth and limit severe manifestation of pulmonary disease. This resulting limitation in pathology may ultimately, limit spread of bacilli and subsequent transmission of organisms between individuals. The current literature is reviewed, and data is presented to support molecular mechanisms underlying lactoferrin's utility as an adjuvant for the BCG vaccine
Generalized partition functions and interpolating statistics
We show that the assumption of quasiperiodic boundary conditions (those that
interpolate continuously periodic and antiperiodic conditions) in order to
compute partition functions of relativistic particles in 2+1 space-time can be
related with anyonic physics. In particular, in the low temperature limit, our
result leads to the well known second virial coefficient for anyons. Besides,
we also obtain the high temperature limit as well as the full temperature
dependence of this coefficient.Comment: 12 pages, Latex, updated and enlarged versio
Thermodynamics of Relativistic Fermions with Chern-Simons Coupling
We study the thermodynamics of the relativistic Quantum Field Theory of
massive fermions in three space-time dimensions coupled to an Abelian
Maxwell-Chern-Simons gauge field. We evaluate the specific heat at finite
temperature and density and find that the variation with the statistical angle
is consistent with the non-relativistic ideas on generalized statistics.Comment: 12 pages, REVTe
Lactoferrin Augmentation of the BCG Vaccine Leads to Increased Pulmonary Integrity
The goal of vaccination to prevent tuberculosis disease (TB) is to offer long-term protection to the individual and the community. In addition, the success of any protective TB vaccine should include the ability to limit cavitary formation and disease progression. The current BCG vaccine protects against disseminated TB disease in children by promoting development of antigenic-specific responses. However, its efficacy is limited in preventing postprimary pulmonary disease in adults that is responsible for the majority of disease and transmission. This paper illustrates the use of lactoferrin as an adjuvant to boost efficacy of the BCG vaccine to control organism growth and limit severe manifestation of pulmonary disease. This resulting limitation in pathology may ultimately, limit spread of bacilli and subsequent transmission of organisms between individuals. The current literature is reviewed, and data is presented to support molecular mechanisms underlying lactoferrin's utility as an adjuvant for the BCG vaccine
Finite Number and Finite Size Effects in Relativistic Bose-Einstein Condensation
Bose-Einstein condensation of a relativistic ideal Bose gas in a rectangular
cavity is studied. Finite size corrections to the critical temperature are
obtained by the heat kernel method. Using zeta-function regularization of
one-loop effective potential, lower dimensional critical temperatures are
calculated. In the presence of strong anisotropy, the condensation is shown to
occur in multisteps. The criteria of this behavior is that critical
temperatures corresponding to lower dimensional systems are smaller than the
three dimensional critical temperature.Comment: 18 pages, 9 figures, Fig.3 replaced, to appear in Physical Review
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