Design, construction, and beam tests of a rotatable collimator prototype for high-intensity and high-energy hadron accelerators

A rotatable-jaw collimator design was conceived as a solution to recover from catastrophic beam impacts which would damage a collimator at the Large Hadron Collider (LHC) or its High-Luminosity upgrade (HL-LHC). One such rotatable collimator prototype was designed and built at SLAC and delivered to CERN for tests with LHC-type circulating beams in the Super Proton Synchrotron (SPS). This was followed by destructive tests at the dedicated High Radiation to Materials (HiRadMat) facility to validate the design and rotation functionality. An overview of the collimator design, together with results from tests without and with beam are presented

International evaluation of the psychometrics of health-related quality of life questionnaires for use among long-term survivors of testicular and prostate cancer

Background: Understanding of the physical, functional and psychosocial health problems and needs of cancer survivors requires cross-national and cross-cultural standardization of health-related quality of life (HRQoL) questionnaires that capture the full range of issues relevant to cancer survivors. To our knowledge, only one study has investigated in a comprehensive way whether a questionnaire used to evaluate HRQoL in cancer patients under active treatment is also reliable and valid when used among (long-term) cancer survivors. In this study we evaluated, in an international context, the psychometrics of HRQoL questionnaires for use among long-term, disease-free, survivors of testicular and prostate cancer. Methods: In this cross-sectional study, we recruited long-term survivors of testicular and prostate cancer from Northern and Southern Europe and from the United Kingdom who had participated in two phase III EORTC clinical trials. Participants completed the SF-36 Health Survey, the EORTC QLQ-C30 questionnaire, the QLQ-PR25 (for prostate cancer) or the QLQ-TC26 (for testicular cancer) questionnaires, and the Impact of Cancer questionnaire. Testicular cancer survivors also completed subscales from the Nordic Questionnaire for Monitoring the Age Diverse Workforce. Results: Two hundred forty-two men (66% response rate) were recruited into the study. The average time since treatment was more than 10 years. Overall, there were few missing questionnaire data, although scales related to sexuality, satisfaction with care and relationship concern

Mission to Mars using integrated propulsion concepts: considerations, opportunities, and strategies

The aim of this paper is to evaluate the feasibility of a mission to Mars using the Integrated Propulsion Systems (IPS) which means to couple Nuclear-MPD-ISPU propulsions ystems. In particular both mission analysis and propulsion aspects are analyzed together with technological aspects. Identifying possible mission scenarios will lead to the study of possible strategies for Mars Exploration and also of methods for reducing cost. As regard to IPS, the coupling between Nuclear Propulsion (Rubbia\u2019s engine) and Superconductive MPD propulsion is considered for the Earth\u2013Mars trajectories: major emphasis is given to the advantages of such a system. The In Situ Resource Utilization (ISRU) concerns on-Mars operations; In Situ Propellant Utilization (ISPU) is foreseen particularly for LOX-CH4 engines for Mars Ascent Vehicles and this possibility is analyzed from a technological point of view. Tether Systems are also considered during interplanetary trajectories and as space elevators on Mars orbit. Finally strategic considerations as sociated to this mission are considered also

Mission to Mars Using Integrated Propulsion Concepts: Considerations, Opportunities, and Strategies

The aim of this paper is to evaluate the feasibility of a mission to Mars using the Integrated Propulsion Systems (IPS) which means to couple Nuclear-MPD-ISPU propulsion systems. In particular both mission analysis and propulsion aspects are analyzed together with technological aspects. Identifying possible mission scenarios will lead to the study of possible strategies for Mars Exploration and also of methods for reducing cost. As regard to IPS, the coupling between Nuclear Propulsion (Rubbia's engine) and Superconductive MPD propulsion is considered for the Earth\u2013Mars trajectories: major emphasis is given to the advantages of such a system. The In Situ Resource Utilization (ISRU) concerns on-Mars operations; In Situ Propellant Utilization (ISPU) is foreseen particularly for LOX-CH4 engines for Mars Ascent Vehicles and this possibility is analyzed from a technological point of view. Tether Systems are also considered during interplanetary trajectories and as space elevators on Mars orbit. Finally strategic considerations associated to this mission are considered also

EFFECTS OF PHYSICAL ACTIVITY IN CHILDREN WITH SEVERE HAEMOPHILIA

Recurring bleeding lead to artropathy with disability. In the past sports and physical activity was denied to children with severe haemophilia for the risk of trauma. Nowadays the preventive administration of lack factor (prophylaxis regimen) guarantees a good hemostatic coverage. Children in prophylaxis will be encouraged to practice sports. The movement strengthens bones and muscles preventing displaced articular motions. Moreover children during physical activity play with peer favoring social integration. Unfortunately Italian law for sports medicine certification is not clear if children with haemophilia (in prophylaxis) can play sports in organized trainings and competition