7 research outputs found
Cerebral venous thrombosis and ischemic stroke with hormonal contraception
Detailed study of risk factors for the development of acute cerebral disorders blood circulation in young people and a description of the clinical case of cerebral venous thrombosis with the occurrence of ischemic stroke in both hemispheres of the brain in a woman of childbearing age while taking the drug combined oral contraceptives. An analysis of one clinical case, which was carried out on the basis of a thorough and painstaking identification of anamnestic data and interpretation of the results of a comprehensive clinical, laboratory and instrumental examination conducted by different specialists β obstetrician / gynecologist, neurologist and therapist. A clinical case of cerebral venous thrombosis is presented in a 31-year-old patient who developed on the background of hormonal contraception, and then entailed the occurrence of an acute ischemic stroke. In women of childbearing age, an increased risk of stroke as a result of cerebral venous thrombosis is associated with the development of prothrombotic conditions caused by the use of combined oral contraceptive pills. Maintaining patients of fertile age by an obstetrician / gynecologist requires interdisciplinary counseling, as well as the selection of alternative methods of contraception.Π¦Π΅Π»Ρ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ β ΠΏΠΎΠ΄ΡΠΎΠ±Π½ΠΎΠ΅ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ ΡΠ°ΠΊΡΠΎΡΠΎΠ² ΡΠΈΡΠΊΠ° ΡΠ°Π·Π²ΠΈΡΠΈΡ ΠΎΡΡΡΡΡ
Π½Π°ΡΡΡΠ΅Π½ΠΈΠΉ ΡΠ΅ΡΠ΅Π±ΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΊΡΠΎΠ²ΠΎΠΎΠ±ΡΠ°ΡΠ΅Π½ΠΈΡ Ρ ΠΌΠΎΠ»ΠΎΠ΄ΡΡ
Π»ΡΠ΄Π΅ΠΉ ΠΈ ΠΎΠΏΠΈΡΠ°Π½ΠΈΠ΅ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΠ»ΡΡΠ°Ρ ΡΠ΅ΡΠ΅Π±ΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ Π²Π΅Π½ΠΎΠ·Π½ΠΎΠ³ΠΎ ΡΡΠΎΠΌΠ±ΠΎΠ·Π° Ρ Π²ΠΎΠ·Π½ΠΈΠΊΠ½ΠΎΠ²Π΅Π½ΠΈΠ΅ΠΌ ΠΈΠ½ΡΠ°ΡΠΊΡΠ° Π² ΠΎΠ±ΠΎΠΈΡ
ΠΏΠΎΠ»ΡΡΠ°ΡΠΈΡΡ
Π³ΠΎΠ»ΠΎΠ²Π½ΠΎΠ³ΠΎ ΠΌΠΎΠ·Π³Π° Ρ ΠΆΠ΅Π½ΡΠΈΠ½Ρ Π΄Π΅ΡΠΎΡΠΎΠ΄Π½ΠΎΠ³ΠΎ Π²ΠΎΠ·ΡΠ°ΡΡΠ° Π½Π° ΡΠΎΠ½Π΅ ΠΏΡΠΈΠ΅ΠΌΠ° Π»Π΅ΠΊΠ°ΡΡΡΠ²Π΅Π½Π½ΠΎΠ³ΠΎ ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΠ° ΠΊΠΎΠΌΠ±ΠΈΠ½ΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
ΠΎΡΠ°Π»ΡΠ½ΡΡ
ΠΊΠΎΠ½ΡΡΠ°ΡΠ΅ΠΏΡΠΈΠ²ΠΎΠ². ΠΡΠΈΠ²Π΅Π΄Π΅Π½ Π°Π½Π°Π»ΠΈΠ· ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΡΠ»ΡΡΠ°Ρ, ΠΊΠΎΡΠΎΡΡΠΉ Π±ΡΠ» ΠΎΡΡΡΠ΅ΡΡΠ²Π»Π΅Π½ Π½Π° ΠΎΡΠ½ΠΎΠ²Π°Π½ΠΈΠΈ Π²ΡΡΠ²Π»Π΅Π½ΠΈΡ Π°Π½Π°ΠΌΠ½Π΅ΡΡΠΈΡΠ΅ΡΠΊΠΈΡ
Π΄Π°Π½Π½ΡΡ
ΠΈ ΠΈΠ½ΡΠ΅ΡΠΏΡΠ΅ΡΠ°ΡΠΈΠΈ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠΎΠ² ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½ΠΎΠ³ΠΎ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ, Π»Π°Π±ΠΎΡΠ°ΡΠΎΡΠ½ΠΎΠ³ΠΎ ΠΈ ΠΈΠ½ΡΡΡΡΠΌΠ΅Π½ΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΎΠ±ΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ, ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½Π½ΠΎΠ³ΠΎ ΡΠΏΠ΅ΡΠΈΠ°Π»ΠΈΡΡΠ°ΠΌΠΈ ΡΠ°Π·Π½ΠΎΠ³ΠΎ ΠΏΡΠΎΡΠΈΠ»Ρ β Π°ΠΊΡΡΠ΅ΡΠΎΠΌ-Π³ΠΈΠ½Π΅ΠΊΠΎΠ»ΠΎΠ³ΠΎΠΌ, Π½Π΅Π²ΡΠΎΠ»ΠΎΠ³ΠΎΠΌ ΠΈ ΡΠ΅ΡΠ°ΠΏΠ΅Π²ΡΠΎΠΌ. ΠΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΠΉ ΡΠ»ΡΡΠ°ΠΉ ΡΠ΅ΡΠ΅Π±ΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ Π²Π΅Π½ΠΎΠ·Π½ΠΎΠ³ΠΎ ΡΡΠΎΠΌΠ±ΠΎΠ·Π° Ρ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΊΠΈ 31 Π³ΠΎΠ΄Π°, ΠΊΠΎΡΠΎΡΡΠΉ ΡΠ°Π·Π²ΠΈΠ»ΡΡ Π½Π° ΡΠΎΠ½Π΅ ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΡ Π³ΠΎΡΠΌΠΎΠ½Π°Π»ΡΠ½ΠΎΠΉ ΠΊΠΎΠ½ΡΡΠ°ΡΠ΅ΠΏΡΠΈΠΈ, Π° Π·Π°ΡΠ΅ΠΌ ΠΏΠΎΠ²Π»Π΅ΠΊ Π·Π° ΡΠΎΠ±ΠΎΠΉ Π²ΠΎΠ·Π½ΠΈΠΊΠ½ΠΎΠ²Π΅Π½ΠΈΠ΅ ΠΎΡΡΡΠΎΠ³ΠΎ Π½Π°ΡΡΡΠ΅Π½ΠΈΡ ΠΌΠΎΠ·Π³ΠΎΠ²ΠΎΠ³ΠΎ ΠΊΡΠΎΠ²ΠΎΠΎΠ±ΡΠ°ΡΠ΅Π½ΠΈΡ ΠΏΠΎ ΠΈΡΠ΅ΠΌΠΈΡΠ΅ΡΠΊΠΎΠΌΡ ΡΠΈΠΏΡ. Π£ ΠΆΠ΅Π½ΡΠΈΠ½ Π΄Π΅ΡΠΎΡΠΎΠ΄Π½ΠΎΠ³ΠΎ Π²ΠΎΠ·ΡΠ°ΡΡΠ° ΠΏΠΎΠ²ΡΡΠ΅Π½Π½ΡΠΉ ΡΠΈΡΠΊ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΠΈΠ½ΡΡΠ»ΡΡΠ° ΠΊΠ°ΠΊ ΡΠ»Π΅Π΄ΡΡΠ²ΠΈΡ ΡΠ΅ΡΠ΅Π±ΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ Π²Π΅Π½ΠΎΠ·Π½ΠΎΠ³ΠΎ ΡΡΠΎΠΌΠ±ΠΎΠ·Π° ΡΠ²ΡΠ·Π°Π½ Ρ ΡΠ°Π·Π²ΠΈΡΠΈΠ΅ΠΌ ΠΏΡΠΎΡΡΠΎΠΌΠ±ΠΎΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠΎΡΡΠΎΡΠ½ΠΈΠΉ, ΠΎΠ±ΡΡΠ»ΠΎΠ²Π»Π΅Π½Π½ΡΡ
ΠΏΡΠΈΠ΅ΠΌΠΎΠΌ ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΠΎΠ² ΠΊΠΎΠΌΠ±ΠΈΠ½ΠΈΡΠΎΠ²Π°Π½Π½ΡΡ
ΠΎΡΠ°Π»ΡΠ½ΡΡ
ΠΊΠΎΠ½ΡΡΠ°ΡΠ΅ΠΏΡΠΈΠ²ΠΎΠ². ΠΠ΅Π΄Π΅Π½ΠΈΠ΅ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠΊ ΡΠ΅ΡΡΠΈΠ»ΡΠ½ΠΎΠ³ΠΎ Π²ΠΎΠ·ΡΠ°ΡΡΠ° Π°ΠΊΡΡΠ΅ΡΠΎΠΌ-Π³ΠΈΠ½Π΅ΠΊΠΎΠ»ΠΎΠ³ΠΎΠΌ ΡΡΠ΅Π±ΡΠ΅Ρ ΠΌΠ΅ΠΆΠ΄ΠΈΡΡΠΈΠΏΠ»ΠΈΠ½Π°ΡΠ½ΠΎΠ³ΠΎ ΠΊΠΎΠ½ΡΡΠ»ΡΡΠΈΡΠΎΠ²Π°Π½ΠΈΡ, Π° ΡΠ°ΠΊΠΆΠ΅ ΠΏΠΎΠ΄Π±ΠΎΡΠ° Π°Π»ΡΡΠ΅ΡΠ½Π°ΡΠΈΠ²Π½ΡΡ
ΠΌΠ΅ΡΠΎΠ΄ΠΎΠ² ΠΊΠΎΠ½ΡΡΠ°ΡΠ΅ΠΏΡΠΈΠΈ
State of cytokine system in ectopic pregnancy
In patients with recurrent ectopic pregnancy in comparison with primary ectopic pregnancy marked by an older age, high infection index, complicated by somatic, obstetrical and gynecological diseases, a higher rate of surgical interventions on the abdominal organs. Inclusion in the complex rehabilitation of local spa factors leads to an sighnificant decrease in the levels of proinflammatory and antiinflammatory cytokines, including IL-4 and TNF-a whit prevent further tissue destruction and proliferation of connective tissue in patients with recurrent and especially with primary ectopic pregnancy.Π£ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠΊ Ρ ΠΏΠΎΠ²ΡΠΎΡΠ½ΠΎΠΉ Π²Π½Π΅ΠΌΠ°ΡΠΎΡΠ½ΠΎΠΉ Π±Π΅ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΡΡΡΡ Π² ΡΡΠ°Π²Π½Π΅Π½ΠΈΠΈ Ρ ΠΏΠ΅ΡΠ²ΠΈΡΠ½ΠΎΠΉ ΠΎΡΠΌΠ΅ΡΠ΅Π½ Π±ΠΎΠ»Π΅Π΅ ΡΡΠ°ΡΡΠΈΠΉ Π²ΠΎΠ·ΡΠ°ΡΡ, Π²ΡΡΠΎΠΊΠΈΠΉ ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΎΠ½Π½ΡΠΉ ΠΈΠ½Π΄Π΅ΠΊΡ, ΠΎΡΠ»ΠΎΠΆΠ½Π΅Π½Π½ΡΠΉ ΡΠΎΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΠΉ, Π°ΠΊΡΡΠ΅ΡΡΠΊΠΈΠΉ ΠΈ Π³ΠΈΠ½Π΅ΠΊΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠΉ Π°Π½Π°ΠΌΠ½Π΅Π·, Π±ΠΎΠ»ΡΡΠ°Ρ ΡΠ°ΡΡΠΎΡΠ° ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠ²Π½ΡΡ
Π²ΠΌΠ΅ΡΠ°ΡΠ΅Π»ΡΡΡΠ² Π½Π° ΠΎΡΠ³Π°Π½Π°Ρ
Π±ΡΡΡΠ½ΠΎΠΉ ΠΏΠΎΠ»ΠΎΡΡΠΈ. ΠΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅ Π² ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡ ΡΠ΅Π°Π±ΠΈΠ»ΠΈΡΠ°ΡΠΈΠΎΠ½Π½ΡΡ
ΠΌΠ΅ΡΠΎΠΏΡΠΈΡΡΠΈΠΉ ΠΌΠ΅ΡΡΠ½ΡΡ
Π±Π°Π»ΡΠ½Π΅ΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠ°ΠΊΡΠΎΡΠΎΠ² ΠΏΡΠΈΠ²ΠΎΠ΄ΠΈΡ ΠΊ Π²ΡΡΠ°ΠΆΠ΅Π½Π½ΠΎΠΌΡ ΡΠ½ΠΈΠΆΠ΅Π½ΠΈΡ ΡΡΠΎΠ²Π½Π΅ΠΉ ΠΏΡΠΎΠ²ΠΎΡΠΏΠ°Π»ΠΈΡΠ΅Π»ΡΠ½ΡΡ
ΠΈ ΠΏΡΠΎΡΠΈΠ²ΠΎΠ²ΠΎΡΠΏΠ°Π»ΠΈΡΠ΅Π»ΡΠ½ΡΡ
ΡΠΈΡΠΎΠΊΠΈΠ½ΠΎΠ², Π² ΡΠΎΠΌ ΡΠΈΡΠ»Π΅ ΠΠ-4 ΠΈ Π€ΠΠ-Π°, ΠΏΡΠ΅Π΄ΠΎΡΠ²ΡΠ°ΡΠ΅Π½ΠΈΡ Π΄Π°Π»ΡΠ½Π΅ΠΉΡΠ΅ΠΉ ΡΠΊΠ°Π½Π΅Π²ΠΎΠΉ Π΄Π΅ΡΡΡΡΠΊΡΠΈΠΈ ΠΈ ΡΠ°Π·ΡΠ°ΡΡΠ°Π½ΠΈΡ ΡΠΎΠ΅Π΄ΠΈΠ½ΠΈΡΠ΅Π»ΡΠ½ΠΎΠΉ ΡΠΊΠ°Π½ΠΈ Ρ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠΎΠΊ Ρ ΠΏΠΎΠ²ΡΠΎΡΠ½ΠΎΠΉ ΠΈ, ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎ, Ρ ΠΏΠ΅ΡΠ²ΠΈΡΠ½ΠΎΠΉ Π²Π½Π΅ΠΌΠ°ΡΠΎΡΠ½ΠΎΠΉ Π±Π΅ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΡΡΡΡ
The results of the study of pain in women with external genital Endometriosis
90 women of reproductive age, including 70 women with pain syndrome of varying severity in external genital endometriosis, were examined to identify the features of pain symptoms. Studied socio-demographic indicators, developed a questionnaire of pain, depending on the nature of pain and the severity of associated symptoms. The results of the study revealed that the intensity of the pain syndrome had no correlation with the localization of the process, the presence or absence of infiltrative growth of endometriosis, the number of endometrioid lesions, and the intensity of the pain syndrome is not related to the duration of the pain. But the duration of the pain syndrome is associated with the degree of prevalence of medium-strength external genital endometriosis correlation significant relationship (r=0.33; p<0.001). Conclusion: Pain syndrome in external genital ndometriosis is associated not only with the pathological process itself, but also with morphological changes in structures, the degree of prevalence of the focal process, forming directly the substrate of pain.ΠΠ±ΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΎ 90 ΠΆΠ΅Π½ΡΠΈΠ½ ΡΠ΅ΠΏΡΠΎΠ΄ΡΠΊΡΠΈΠ²Π½ΠΎΠ³ΠΎ Π²ΠΎΠ·ΡΠ°ΡΡΠ°, ΠΈΠ· ΠΊΠΎΡΠΎΡΡΡ
70 ΠΆΠ΅Π½ΡΠΈΠ½ Ρ Π±ΠΎΠ»Π΅Π²ΡΠΌ ΡΠΈΠ½Π΄ΡΠΎΠΌΠΎΠΌ ΡΠ°Π·Π»ΠΈΡΠ½ΠΎΠΉ ΡΡΠ΅ΠΏΠ΅Π½ΠΈ ΡΡΠΆΠ΅ΡΡΠΈ Π½Π° ΡΠΎΠ½Π΅ Π½Π°ΡΡΠΆΠ½ΠΎΠ³ΠΎ Π³Π΅Π½ΠΈΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠ½Π΄ΠΎΠΌΠ΅ΡΡΠΈΠΎΠ·Π°, Ρ ΡΠ΅Π»ΡΡ Π²ΡΡΠ²Π»Π΅Π½ΠΈΡ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ Π±ΠΎΠ»Π΅Π²ΠΎΠΉ ΡΠΈΠΌΠΏΡΠΎΠΌΠ°ΡΠΈΠΊΠΈ. ΠΠ·ΡΡΠ΅Π½Ρ ΡΠΎΡΠΈΠ°Π»ΡΠ½ΠΎ-Π΄Π΅ΠΌΠΎΠ³ΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΏΠΎΠΊΠ°Π·Π°ΡΠ΅Π»ΠΈ, ΡΠ°Π·ΡΠ°Π±ΠΎΡΠ°Π½Π° Π°Π½ΠΊΠ΅ΡΠ° Π±ΠΎΠ»Π΅Π²ΡΡ
ΠΎΡΡΡΠ΅Π½ΠΈΠΉ Π² Π·Π°Π²ΠΈΡΠΈΠΌΠΎΡΡΠΈ ΠΎΡ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠ° Π±ΠΎΠ»ΠΈ ΠΈ Π²ΡΡΠ°ΠΆΠ΅Π½Π½ΠΎΡΡΠΈ ΡΠΎΠΏΡΡΡΡΠ²ΡΡΡΠΈΡ
ΡΠΈΠΌΠΏΡΠΎΠΌΠΎΠ². ΠΠΎ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ°ΠΌ ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΡ Π²ΡΡΠ²Π»Π΅Π½ΠΎ, ΡΡΠΎ ΠΈΠ½ΡΠ΅Π½ΡΠΈΠ²Π½ΠΎΡΡΡ Π±ΠΎΠ»Π΅Π²ΠΎΠ³ΠΎ ΡΠΈΠ½Π΄ΡΠΎΠΌΠ° Π½Π΅ ΠΈΠΌΠ΅Π»Π° ΠΊΠΎΡΡΠ΅Π»ΡΡΠΈΠΎΠ½Π½ΡΡ ΡΠ²ΡΠ·Ρ Ρ Π»ΠΎΠΊΠ°Π»ΠΈΠ·Π°ΡΠΈΠ΅ΠΉ ΠΏΡΠΎΡΠ΅ΡΡΠ°, Π½Π°Π»ΠΈΡΠΈΡ ΠΈΠ»ΠΈ ΠΎΡΡΡΡΡΡΠ²ΠΈΡ ΠΈΠ½ΡΠΈΠ»ΡΡΡΠ°ΡΠΈΠ²Π½ΠΎΠ³ΠΎ ΡΠΎΡΡΠ° ΡΠ½Π΄ΠΎΠΌΠ΅ΡΡΠΈΠΎΠ·Π°, ΠΎΡ ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²Π° ΡΠ½Π΄ΠΎΠΌΠ΅ΡΡΠΈΠΎΠΈΠ΄Π½ΡΡ
ΠΎΡΠ°Π³ΠΎΠ² ΠΏΠΎΡΠ°ΠΆΠ΅Π½ΠΈΡ, Π° ΡΠ°ΠΊΠΆΠ΅ ΠΈΠ½ΡΠ΅Π½ΡΠΈΠ²Π½ΠΎΡΡΡ Π±ΠΎΠ»Π΅Π²ΠΎΠ³ΠΎ ΡΠΈΠ½Π΄ΡΠΎΠΌΠ° Π½Π΅ ΡΠ²ΡΠ·Π°Π½Π° Ρ Π΄Π»ΠΈΡΠ΅Π»ΡΠ½ΠΎΡΡΡΡ Π±ΠΎΠ»ΠΈ. ΠΠΎ Π΄Π»ΠΈΡΠ΅Π»ΡΠ½ΠΎΡΡΡ Π±ΠΎΠ»Π΅Π²ΠΎΠ³ΠΎ ΡΠΈΠ½Π΄ΡΠΎΠΌΠ° ΡΠ²ΡΠ·Π°Π½Π° ΡΠΎ ΡΡΠ΅ΠΏΠ΅Π½ΡΡ ΡΠ°ΡΠΏΡΠΎΡΡΡΠ°Π½Π΅Π½Π½ΠΎΡΡΠΈ Π½Π°ΡΡΠΆΠ½ΠΎΠ³ΠΎ Π³Π΅Π½ΠΈΡΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠ½Π΄ΠΎΠΌΠ΅ΡΡΠΈΠΎΠ·Π° ΡΡΠ΅Π΄Π½Π΅ΠΉ ΡΠΈΠ»Ρ ΠΊΠΎΡΡΠ΅Π»ΡΡΠΈΠΎΠ½Π½ΠΎΠΉ Π΄ΠΎΡΡΠΎΠ²Π΅ΡΠ½ΠΎΠΉ ΡΠ²ΡΠ·ΡΡ (r=0,33; p<0,001). ΠΡΠ²ΠΎΠ΄: ΠΠΎΠ»Π΅Π²ΠΎΠΉ ΡΠΈΠ½Π΄ΡΠΎΠΌ ΠΏΡΠΈ Π½Π°ΡΡΠΆΠ½ΠΎΠΌ Π³Π΅Π½ΠΈΡΠ°Π»ΡΠ½ΠΎΠΌ ΡΠ½Π΄ΠΎΠΌΠ΅ΡΡΠΈΠΎΠ·Π΅ ΡΠ²ΡΠ·Π°Π½ Π½Π΅ ΡΠΎΠ»ΡΠΊΠΎ Ρ ΡΠ°ΠΌΠΈΠΌ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠΌ ΠΏΡΠΎΡΠ΅ΡΡΠΎΠΌ, Π½ΠΎ ΠΈ Ρ ΠΌΠΎΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠΌΠΈ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΡΠΌΠΈ ΡΡΡΡΠΊΡΡΡ, ΡΡΠ΅ΠΏΠ΅Π½ΡΡ ΡΠ°ΡΠΏΡΠΎΡΡΡΠ°Π½Π΅Π½Π½ΠΎΡΡΠΈ ΠΎΡΠ°Π³ΠΎΠ²ΠΎΠ³ΠΎ ΠΏΡΠΎΡΠ΅ΡΡΠ°, ΡΠΎΡΠΌΠΈΡΡΡ Π½Π΅ΠΏΠΎΡΡΠ΅Π΄ΡΡΠ²Π΅Π½Π½ΠΎ ΡΡΠ±ΡΡΡΠ°Ρ Π±ΠΎΠ»ΠΈ
The efficacy evaluation of proposed treatment policy and anemia prevention among teenage girls
A clinical blood analysis of 462 teenage girls was ascertain. As a result, the main group, which consisted of 110 teenage girls with iron deficiency anemia the age of 12-17, was formed. In order to compare results, experimental group (control group), which consisted of 50 healthy teenage girls, was formed. Implementation of the complex treatment (hemostatic and, in some cases, hormonal cure in combination with iron preparation) led to a positive result in health of teenage girls with anemia.Π£ 462 Π΄Π΅Π²ΡΡΠ΅ΠΊ-ΠΏΠΎΠ΄ΡΠΎΡΡΠΊΠΎΠ² Π±ΡΠ» ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ ΠΎΠ±ΡΠΈΠΉ Π°Π½Π°Π»ΠΈΠ· ΠΊΡΠΎΠ²ΠΈ. Π ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΠ΅ ΡΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π»Π°ΡΡ ΠΎΡΠ½ΠΎΠ²Π½Π°Ρ Π³ΡΡΠΏΠΏΠ°, ΡΠΎΡΡΠΎΡΡΠ°Ρ ΠΈΠ· 110 Π΄Π΅Π²ΡΡΠ΅ΠΊ-ΠΏΠΎΠ΄ΡΠΎΡΡΠΊΠΎΠ² Ρ ΠΆΠ΅Π»Π΅Π·ΠΎΠ΄Π΅ΡΠΈΡΠΈΡΠ½ΠΎΠΉ Π°Π½Π΅ΠΌΠΈΠ΅ΠΉ Π² Π²ΠΎΠ·ΡΠ°ΡΡΠ΅ ΠΎΡ 12 Π΄ΠΎ 17 Π»Π΅Ρ. Π‘ ΡΠ΅Π»ΡΡ ΡΠΎΠΏΠΎΡΡΠ°Π²Π»Π΅Π½ΠΈΡ Π΄Π°Π½Π½ΡΡ
Π±ΡΠ»Π° ΡΡΠΎΡΠΌΠΈΡΠΎΠ²Π°Π½Π° Π³ΡΡΠΏΠΏΠ° ΡΡΠ°Π²Π½Π΅Π½ΠΈΡ (ΠΊΠΎΠ½ΡΡΠΎΠ»ΡΠ½Π°Ρ Π³ΡΡΠΏΠΏΠ°) - 50 Π·Π΄ΠΎΡΠΎΠ²ΡΡ
Π΄Π΅Π²ΡΡΠ΅ΠΊ-ΠΏΠΎΠ΄ΡΠΎΡΡΠΊΠΎΠ². ΠΡΠΎΠ²Π΅Π΄Π΅Π½ΠΈΠ΅ ΠΊΠΎΠΌΠΏΠ»Π΅ΠΊΡΠ½ΠΎΠ³ΠΎ Π»Π΅ΡΠ΅Π½ΠΈΡ (Π³Π΅ΠΌΠΎΡΡΠ°ΡΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΈ Π² ΠΎΡΠ΄Π΅Π»ΡΠ½ΡΡ
ΡΠ»ΡΡΠ°ΡΡ
Π³ΠΎΡΠΌΠΎΠ½Π°Π»ΡΠ½ΡΠ΅ ΡΡΠ΅Π΄ΡΡΠ²Π° Π² ΡΠΎΡΠ΅ΡΠ°Π½ΠΈΠΈ Ρ ΠΏΡΠ΅ΠΏΠ°ΡΠ°ΡΠ°ΠΌΠΈ ΠΆΠ΅Π»Π΅Π·Π°) ΠΏΡΠΈΠ²Π΅Π»ΠΎ ΠΊ ΠΏΠΎΠ»ΠΎΠΆΠΈΡΠ΅Π»ΡΠ½ΠΎΠΌΡ ΡΠ΅Π·ΡΠ»ΡΡΠ°ΡΡ Ρ Π΄Π΅Π²ΡΡΠ΅ΠΊ-ΠΏΠΎΠ΄ΡΠΎΡΡΠΊΠΎΠ² Ρ Π°Π½Π΅ΠΌΠΈΠ΅ΠΉ
About the study the clinical data in women in early natural and surgical postmenopausal women
Climacteric syndrome remains an urgent problem today. The climax is both the norm and disease: the norm because the menopause in the female body is a natural phenomenon, but a disease because it is a persistent violation of the regulation, leading eventually to decreased viability of the organism. We examined 207 women aged 40-55 years with climacteric syndrome in early natural (110 women) and surgical postmenopausal (97 women). The study of clinical data revealed some differences in the occurrence of menopausal women in early natural and surgical postmenopausal women.ΠΠ»ΠΈΠΌΠ°ΠΊΡΠ΅ΡΠΈΡΠ΅ΡΠΊΠΈΠΉ ΡΠΈΠ½Π΄ΡΠΎΠΌ ΠΎΡΡΠ°Π΅ΡΡΡ Π°ΠΊΡΡΠ°Π»ΡΠ½ΠΎΠΉ ΠΏΡΠΎΠ±Π»Π΅ΠΌΠΎΠΉ ΠΈ Π½Π° ΡΠ΅Π³ΠΎΠ΄Π½ΡΡΠ½ΠΈΠΉ Π΄Π΅Π½Ρ. ΠΊΠ»ΠΈΠΌΠ°ΠΊΡ ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΎΠ΄Π½ΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎ ΠΈ Π½ΠΎΡΠΌΠΎΠΉ ΠΈ Π±ΠΎΠ»Π΅Π·Π½ΡΡ: Π½ΠΎΡΠΌΠΎΠΉ ΠΏΠΎΡΠΎΠΌΡ, ΡΡΠΎ ΠΊΠ»ΠΈΠΌΠ°ΠΊΡ Π² ΠΆΠ΅Π½ΡΠΊΠΎΠΌ ΠΎΡΠ³Π°Π½ΠΈΠ·ΠΌΠ΅ ΡΠ²Π»Π΅Π½ΠΈΠ΅ Π·Π°ΠΊΠΎΠ½ΠΎΠΌΠ΅ΡΠ½ΠΎΠ΅, Π° Π±ΠΎΠ»Π΅Π·Π½ΡΡ ΠΏΠΎΡΠΎΠΌΡ, ΡΡΠΎ ΡΡΠΎ ΡΡΠΎΠΉΠΊΠΎΠ΅ Π½Π°ΡΡΡΠ΅Π½ΠΈΠ΅ ΡΠ΅Π³ΡΠ»ΡΡΠΈΠΈ, ΠΏΡΠΈΠ²ΠΎΠ΄ΡΡΠ΅Π΅ Π² ΠΊΠΎΠ½Π΅ΡΠ½ΠΎΠΌ ΠΈΡΠΎΠ³Π΅ ΠΊ ΡΠ½ΠΈΠΆΠ΅Π½ΠΈΡ ΠΆΠΈΠ·Π½Π΅ΡΠΏΠΎΡΠΎΠ±Π½ΠΎΡΡΠΈ ΠΎΡΠ³Π°Π½ΠΈΠ·ΠΌΠ°. ΠΠ°ΠΌΠΈ Π±ΡΠ»ΠΎ ΠΎΠ±ΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΎ 207 ΠΆΠ΅Π½ΡΠΈΠ½ Π² Π²ΠΎΠ·ΡΠ°ΡΡΠ΅ 40-55 Π»Π΅Ρ Ρ ΠΊΠ»ΠΈΠΌΠ°ΠΊΡΠ΅ΡΠΈΡΠ΅ΡΠΊΠΈΠΌ ΡΠΈΠ½Π΄ΡΠΎΠΌΠΎΠΌ Π² ΡΠ°Π½Π½Π΅ΠΉ Π΅ΡΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΠΉ (110 ΠΆΠ΅Π½ΡΠΈΠ½) ΠΈ Ρ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΏΠΎΡΡΠΌΠ΅Π½ΠΎΠΏΠ°ΡΠ·Π΅ (97 ΠΆΠ΅Π½ΡΠΈΠ½). ΠΠ·ΡΡΠ΅Π½ΠΈΠΈ ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΡ
Π΄Π°Π½Π½ΡΡ
Π²ΡΡΠ²ΠΈΠ»ΠΎ Π½Π΅ΠΊΠΎΡΠΎΡΡΠ΅ ΡΠ°Π·Π»ΠΈΡΠΈΡ Π² ΠΏΡΠΎΡΠ΅ΠΊΠ°Π½ΠΈΠΈ ΠΌΠ΅Π½ΠΎΠΏΠ°ΡΠ·Ρ Ρ ΠΆΠ΅Π½ΡΠΈΠ½ Π² ΡΠ°Π½Π½Π΅ΠΉ Π΅ΡΡΠ΅ΡΡΠ²Π΅Π½Π½ΠΎΠΉ ΠΈ Ρ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΏΠΎΡΡΠΌΠ΅Π½ΠΎΠΏΠ°ΡΠ·Π΅
To the question about the study of genetic factors of cardiovascular diseases in women of postmenopausal age
Cardiovascular disease is one of the most frequent reasons of death among the women of menopausal age. In addition to the hormonal disorders, which is accompanying this period of life, there is no doubt in presence of genetic predisposition to the development of cardiovascular diseases. The connection between the risk of the development of cardiovascular diseases and increased levels of PAI-1 in the blood, due to the presence of the 4G allele of PAI-1 and genetic polymorphism of MTHFR in genotype, was examined in this article. The study of genetic factors, which play a role in the development of cardiovascular diseases, indicates, that women of postmenopausal age are at the high risk of the listed diseases, and this should be considered during the selecting the optimal method of treatment of menopausal disorders.Π‘Π΅ΡΠ΄Π΅ΡΠ½ΠΎ-ΡΠΎΡΡΠ΄ΠΈΡΡΠ°Ρ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡ ΡΠ²Π»ΡΠ΅ΡΡΡ ΠΎΠ΄Π½ΠΎΠΉ ΠΈΠ· ΡΠ°ΠΌΡΡ
ΡΠ°ΡΡΡΡ
ΠΏΡΠΈΡΠΈΠ½ ΡΠΌΠ΅ΡΡΠ½ΠΎΡΡΠΈ ΠΆΠ΅Π½ΡΠΈΠ½ ΠΊΠ»ΠΈΠΌΠ°ΠΊΡΠ΅ΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π²ΠΎΠ·ΡΠ°ΡΡΠ°. ΠΠΎΠΌΠΈΠΌΠΎ Π³ΠΎΡΠΌΠΎΠ½Π°Π»ΡΠ½ΡΡ
Π½Π°ΡΡΡΠ΅Π½ΠΈΠΉ, ΡΠΎΠΏΡΡΡΡΠ²ΡΡΡΠΈΡ
ΡΡΠΎΠΌΡ ΠΏΠ΅ΡΠΈΠΎΠ΄Ρ ΠΆΠΈΠ·Π½ΠΈ, Π² Π½Π°ΡΡΠΎΡΡΠ΅Π΅ Π²ΡΠ΅ΠΌΡ Π½Π΅Ρ ΡΠΎΠΌΠ½Π΅Π½ΠΈΠΉ Π² Π½Π°Π»ΠΈΡΠΈΠΈ Π³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΏΡΠ΅Π΄ΡΠ°ΡΠΏΠΎΠ»ΠΎΠΆΠ΅Π½Π½ΠΎΡΡΠΈ ΠΊ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΡΠ΅ΡΠ΄Π΅ΡΠ½ΠΎ-ΡΠΎΡΡΠ΄ΠΈΡΡΡΡ
Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ. Π Π΄Π°Π½Π½ΠΎΠΉ ΡΡΠ°ΡΡΠ΅ ΡΠ°ΡΡΠΌΠ°ΡΡΠΈΠ²Π°Π΅ΡΡΡ ΡΠ²ΡΠ·Ρ ΠΌΠ΅ΠΆΠ΄Ρ ΡΠΈΡΠΊΠΎΠΌ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΡΠ΅ΡΠ΄Π΅ΡΠ½ΠΎ-ΡΠΎΡΡΠ΄ΠΈΡΡΡΡ
Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ ΠΈ ΠΏΠΎΠ²ΡΡΠ΅Π½ΠΈΠ΅ΠΌ ΡΡΠΎΠ²Π½Ρ Π ΠΠ Π² ΠΊΡΠΎΠ²ΠΈ, ΠΎΠ±ΡΡΠ»ΠΎΠ²Π»Π΅Π½Π½ΠΎΠ³ΠΎ ΠΏΡΠΈΡΡΡΡΡΠ²ΠΈΠ΅ΠΌ Π² ΠΈΡ
Π³Π΅Π½ΠΎΡΠΈΠΏΠ΅ -4G Π°Π»Π»Π΅Π»Ρ Π³Π΅Π½Π° Π ΠΠ ΠΈ Π³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ ΠΏΠΎΠ»ΠΈΠΌΠΎΡΡΠΈΠ·ΠΌΠ° ΠΠ’ΠΠ€Π . ΠΡΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΈΠ΅ Π³Π΅Π½Π΅ΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠ°ΠΊΡΠΎΡΠΎΠ², ΠΈΠ³ΡΠ°ΡΡΠΈΡ
ΡΠΎΠ»Ρ Π² ΡΠ°Π·Π²ΠΈΡΠΈΠΈ ΡΠ΅ΡΠ΄Π΅ΡΠ½ΠΎ-ΡΠΎΡΡΠ΄ΠΈΡΡΡΡ
Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ, ΡΠ²ΠΈΠ΄Π΅ΡΠ΅Π»ΡΡΡΠ²ΡΡΡ ΠΎ ΡΠΎΠΌ, ΡΡΠΎ ΠΆΠ΅Π½ΡΠΈΠ½Ρ ΠΏΠΎΡΡΠΌΠ΅Π½ΠΎΠΏΠ°ΡΠ·Π°Π»ΡΠ½ΠΎΠ³ΠΎ Π²ΠΎΠ·ΡΠ°ΡΡΠ° ΡΠΎΡΡΠ°Π²Π»ΡΡΡ Π³ΡΡΠΏΠΏΡ Π²ΡΡΠΎΠΊΠΎΠ³ΠΎ ΡΠΈΡΠΊΠ° ΠΏΠΎ ΠΏΠ΅ΡΠ΅ΡΠΈΡΠ»Π΅Π½Π½ΡΠΌ Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΡΠΌ ΠΈ ΡΡΠΎ Π½Π΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΠΎ ΡΡΠΈΡΡΠ²Π°ΡΡ ΠΏΡΠΈ Π²ΡΠ±ΠΎΡΠ΅ ΠΎΠΏΡΠΈΠΌΠ°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΌΠ΅ΡΠΎΠ΄Π° Π»Π΅ΡΠ΅Π½ΠΈΡ ΠΌΠ΅Π½ΠΎΠΏΠ°ΡΠ·Π°Π»ΡΠ½ΡΡ
ΡΠ°ΡΡΡΡΠΎΠΉΡΡΠ²
Features of clinical data in women in early surgical postmenopausal women
Surgical deactivation of ovarian function in women of reproductive age remains one of the urgent problems of modern medicine. This analysis was performed in 60 women of the main group aged 40-55 years in early surgical postmenopausal women who underwent abdominal gynecological operations with ovarian excision. Indications for surgical interventions on the organs of the reproductive system in women are ovarian tumors, combined pathology of the reproductive system, severe purulent processes of the genitals and others, the volume of which includes removal of the ovaries.Π₯ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ΅ Π²ΡΠΊΠ»ΡΡΠ΅Π½ΠΈΠ΅ ΡΡΠ½ΠΊΡΠΈΠΈ ΡΠΈΡΠ½ΠΈΠΊΠΎΠ² Ρ ΠΆΠ΅Π½ΡΠΈΠ½ ΡΠ΅ΠΏΡΠΎΠ΄ΡΠΊΡΠΈΠ²Π½ΠΎΠ³ΠΎ Π²ΠΎΠ·ΡΠ°ΡΡΠ° ΠΎΡΡΠ°Π΅ΡΡΡ ΠΎΠ΄Π½ΠΎΠΉ ΠΈΠ· Π°ΠΊΡΡΠ°Π»ΡΠ½ΡΡ
ΠΏΡΠΎΠ±Π»Π΅ΠΌ ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΠΎΠΉ ΠΌΠ΅Π΄ΠΈΡΠΈΠ½Ρ. ΠΠ°Π½Π½ΡΠΉ Π°Π½Π°Π»ΠΈΠ· Π±ΡΠ» ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ Ρ 60 ΠΆΠ΅Π½ΡΠΈΠ½ ΠΎΡΠ½ΠΎΠ²Π½ΠΎΠΉ Π³ΡΡΠΏΠΏΡ Π² Π²ΠΎΠ·ΡΠ°ΡΡΠ΅ ΠΎΡ 40 Π΄ΠΎ 55 Π»Π΅Ρ Π² ΡΠ°Π½Π½Π΅ΠΉ Ρ
ΠΈΡΡΡΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΏΠΎΡΡΠΌΠ΅Π½ΠΎΠΏΠ°ΡΠ·Π΅, ΠΊΠΎΡΠΎΡΡΠ΅ ΠΏΠ΅ΡΠ΅Π½Π΅ΡΠ»ΠΈ Π°Π±Π΄ΠΎΠΌΠΈΠ½Π°Π»ΡΠ½ΡΠ΅ Π³ΠΈΠ½Π΅ΠΊΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΠ΅ ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠΈ Ρ ΡΠ΄Π°Π»Π΅Π½ΠΈΠ΅ΠΌ ΡΠΈΡΠ½ΠΈΠΊΠΎΠ². ΠΠΎΠΊΠ°Π·Π°Π½ΠΈΡΠΌΠΈ Π΄Π»Ρ ΠΎΠΏΠ΅ΡΠ°ΡΠΈΠ²Π½ΡΡ
Π²ΠΌΠ΅ΡΠ°ΡΠ΅Π»ΡΡΡΠ² Π½Π° ΠΎΡΠ³Π°Π½Π°Ρ
ΡΠ΅ΠΏΡΠΎΠ΄ΡΠΊΡΠΈΠ²Π½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ Ρ ΠΆΠ΅Π½ΡΠΈΠ½ ΡΠ²Π»ΡΡΡΡΡ ΠΎΠΏΡΡ
ΠΎΠ»ΠΈ ΡΠΈΡΠ½ΠΈΠΊΠΎΠ², ΡΠΎΡΠ΅ΡΠ°Π½Π½Π°Ρ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΡ ΠΏΠΎΠ»ΠΎΠ²ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ, ΡΡΠΆΠ΅Π»ΡΠ΅ Π³Π½ΠΎΠΉΠ½ΡΠ΅ ΠΏΡΠΎΡΠ΅ΡΡΡ Π³Π΅Π½ΠΈΡΠ°Π»ΠΈΠΉ ΠΈ Π΄ΡΡΠ³ΠΈΠ΅, ΠΎΠ±ΡΠ΅ΠΌ ΠΊΠΎΡΠΎΡΡΡ
Π²ΠΊΠ»ΡΡΠ°Π΅Ρ ΡΠ΄Π°Π»Π΅Π½ΠΈΠ΅ ΡΠΈΡΠ½ΠΈΠΊΠΎΠ²