Quantum Cosmology and Open Universes

Quantum creation of Universes with compact spacelike sections that have curvature $k$ either closed, flat or open, i.e. $k=\pm1,0$ are studied. In the flat and open cases, the superpotential of the Wheeler De Witt equation is significantly modified, and as a result the qualitative behaviour of a typical wavefunction differs from the traditional closed case. Using regularity arguments, it is shown that the only consistent state for the wavefunction is the Tunneling one. By computing the quantum probabilities for the curvature of the sections, it is shown that quantum cosmology actually favours that the Universe be open, $k=-1$. In all cases sufficient inflation $\sim 60$ e-foldings is predicted: this is an improvement over classical measures that generally are ambiguous as to whether inflation is certain to occur.Comment: 11 pages, Revtex, 7 figures. Accepted for publication in PRD. New material and important corrections added in response to referee's repor

Dyson summation without violating Ward identities and the Goldstone-boson equivalence theorem

In contrast to the conventional treatment of gauge theories, in the background-field method the Ward identities for connected Green functions are not violated by Dyson summation of self-energies in finite orders of perturbation theory. Thus, Dyson summation does not spoil gauge cancelations at high energies which are ruled by the Goldstone-boson equivalence theorem. Moreover, in the background-field method the precise formulation of the equivalence theorem in higher orders (including questions of renormalization) is simplified rendering actual calculations easier. Finally, the equivalence theorem is also formulated for the Standard Model with a non-linearly realized scalar sector and for the gauged non-linear $\sigma$-model.Comment: 26 pages, latex, complete ps-file available via anonymous ftp from ftp://ftp.physik.uni-wuerzburg.de/pub/preprint/1996/WUE-ITP-96-002.ps, reference added and some comments on Ref.[6] modifie

Obesity prevention and personal responsibility: the case of front-of-pack food labelling in Australia

<p>Abstract</p> <p>Background</p> <p>In Australia, the food industry and public health groups are locked in serious struggle for regulatory influence over the terms of front-of-pack food labelling. Clear, unambiguous labelling of the nutritional content of pre-packaged foods and of standardized food items sold in chain restaurants is consistent with the prevailing philosophy of 'personal responsibility'. An interpretive, front-of-pack labelling scheme has the capacity to encourage healthier patterns of eating, and to be a catalyst for improvements in the nutritional quality of food products through re-formulation. On the other hand, the strength of opposition of the Australian Food and Grocery Council to 'Traffic Light Labelling', and its efforts to promote a non-interpretive, voluntary scheme, invite the interpretation that the food industry is resistant to any reforms that could destabilise current (unhealthy) purchasing patterns and the revenues they represent.</p> <p>Discussion</p> <p>This article argues that although policies that aim to educate consumers about the nutritional content of food are welcome, they are only one part of a broader basket of policies that are needed to make progress on obesity prevention and public health nutrition. However, to the extent that food labelling has the capacity to inform and empower consumers to make healthier choices - and to be a catalyst for improving the nutritional quality of commercial recipes - it has an important role to play. Furthermore, given the dietary impact of meals eaten in fast food and franchise restaurants, interpretive labelling requirements should not be restricted to pre-packaged foods.</p> <p>Summary</p> <p>Food industry resistance to an interpretive food labelling scheme is an important test for government, and a case study of how self-interest prompts industry to promote weaker, voluntary schemes that pre-empt and undermine progressive public health regulation.</p

Theories of schizophrenia: a genetic-inflammatory-vascular synthesis

BACKGROUND: Schizophrenia, a relatively common psychiatric syndrome, affects virtually all brain functions yet has eluded explanation for more than 100 years. Whether by developmental and/or degenerative processes, abnormalities of neurons and their synaptic connections have been the recent focus of attention. However, our inability to fathom the pathophysiology of schizophrenia forces us to challenge our theoretical models and beliefs. A search for a more satisfying model to explain aspects of schizophrenia uncovers clues pointing to genetically mediated CNS microvascular inflammatory disease. DISCUSSION: A vascular component to a theory of schizophrenia posits that the physiologic abnormalities leading to illness involve disruption of the exquisitely precise regulation of the delivery of energy and oxygen required for normal brain function. The theory further proposes that abnormalities of CNS metabolism arise because genetically modulated inflammatory reactions damage the microvascular system of the brain in reaction to environmental agents, including infections, hypoxia, and physical trauma. Damage may accumulate with repeated exposure to triggering agents resulting in exacerbation and deterioration, or healing with their removal. There are clear examples of genetic polymorphisms in inflammatory regulators leading to exaggerated inflammatory responses. There is also ample evidence that inflammatory vascular disease of the brain can lead to psychosis, often waxing and waning, and exhibiting a fluctuating course, as seen in schizophrenia. Disturbances of CNS blood flow have repeatedly been observed in people with schizophrenia using old and new technologies. To account for the myriad of behavioral and other curious findings in schizophrenia such as minor physical anomalies, or reported decreased rates of rheumatoid arthritis and highly visible nail fold capillaries, we would have to evoke a process that is systemic such as the vascular and immune/inflammatory systems. SUMMARY: A vascular-inflammatory theory of schizophrenia brings together environmental and genetic factors in a way that can explain the diversity of symptoms and outcomes observed. If these ideas are confirmed, they would lead in new directions for treatments or preventions by avoiding inducers of inflammation or by way of inflammatory modulating agents, thus preventing exaggerated inflammation and consequent triggering of a psychotic episode in genetically predisposed persons