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Not AvailableFifty years ago, the green revolution increased agricultural production worldwide, saving millions of people from starvation and undernourishment. To enhance plant growth and nutrition, plant growth-promoting rhizobacteria (PGPR) plays a significant role in the intensively managed agricultural systems. The rising demand for crop production with a significant reduction in synthetic chemical fertilizers and pesticide use is a challenge. Plant growth-promoting rhizobacteria (PGPR) are those microorganisms that live within a rhizospheric zone of plant host in a symbiosis relationship. PGPRis beneficial microorganism to plant that can protect it from deleterious effects of environmental stresses such as drought, salinity, flooding, and phytopathogens. The mechanisms of PGPR include curbing hormonal and nutritional harmony, inducing systemic resistance against phytopathogens, and solubilizing nutrients for easy uptake by crops. Molecular tools showed great potential in the identification and tracking of the phylogeny of soil microbes. Today is the era of omics which including genomics, transcriptomics, proteomics and metabolomics, these omics helps us to the better understanding of the PGPRs function and their interaction with the host. Proteomics enhances the knowledge of the gene (s) and pathways induced during the host-PGPR interaction. The 2D-PAGE strategy has been widely used in understanding stress responses as well as in understanding constitutive differences between developmental stages or genotypes.it provides a broad overview of proteins produced by both the partners.Not Availabl