Loeffler's Syndrome and Multifocal Cutaneous Larva Migrans: Case report of an uncommon occurrence and review of the literature

Cutaneous larva migrans (CLM) is a zoonotic skin disease that is frequently diagnosed in tropical and subtropical countries. Loeffler’s syndrome (LS) is a transient respiratory ailment characterized by pulmonary infiltration along with peripheral eosinophilia and commonly follows parasitic infestation. We report here an interesting case of a patient presenting with LS that was attributed secondary to multifocal CLM. Treatment with seven-day course of oral albendazole (400mg daily) coupled with nebulization (levosalbutamol and budesonide) led to complete resolution of cutaneous lesions and respiratory complaints in two weeks. There was complete resolution of pulmonary pathology at 4 weeks follow-up. As there are only a few reported cases of LS associated with CLM, we also reviewed the literature on this rare association. Keywords: Loeffler's syndrome; peripheral eosinophilia; cutaneous larva migrans; multifocal; disseminated; helminths, albendazole