Synthesis of novel antimicrobial aryl himachalene derivatives from naturally occurring himachalenes

Five new 2,9,9-trimethyl-6,7,8,9-tetrahydro-benzocyclohepten-5-ylidene-amine derivatives (16a-16e) were synthesized from α-dehydro-ar-himachalene (11) that was originally prepared from an isomeric mixture of α, β and γ himachalenes (10), the abundant sesquiterpenes of Cedrus deodara essential oil. In addition, different aryl himachalenes derivatives (9, 12, 14 and 15) were also formed from 11. The structures of the synthesized compounds were confirmed on the basis of their NMR, IR and mass spectral data. The prepared compounds were tested against a group of sixteen organisms including gram positive and gram negative bacterial and fungal strains. The introduction of a series of substituted imine groups into aryl himachalenes at 5th position (16a-16e) enhanced antimicrobial activity as compared to the aromatized derivatives (9, 12, 14 and 15) against gram-positive bacteria Bacillus subtilis, Micrococcus luteus and Staphylococcus aureus, and mycotoxigenic fungi Aspergillus parasiticus, A. ochraceous and A. sydowii

Synthesis of 5-[o-(10-phenylisoalloxazine-3-acetamido)phenyl]-10,15,20-triphenylporphyrin

172-17

Chemical Composition and Larvicidal Activities of the Himalayan Cedar, Cedrus deodara Essential Oil and Its Fractions Against the Diamondback Moth, Plutella xylostella

Plants and plant-derived materials play an extremely important role in pest management programs. Essential oil from wood chips of Himalayan Cedar, Cedrus deodara (Roxburgh) Don (Pinales: Pinaceae), was obtained by hydrodistillation and fractionated to pentane and acetonitrile from which himachalenes and atlantones enriched fractions were isolated. A total of forty compounds were identified from these fractions using GC and GC-MS analyses. Essential oils and fractions were evaluated for insecticidal activities against second instars of the diamondback moth, Plutella xylostella L. (Lepidoptera: Yponomeutidae), using a leaf dip method. All samples showed promising larvicidal activity against larvae of P. xylostella. The pentane fraction was the most toxic with a LC50 value of 287 µg/ml. The himachalenes enriched fraction was more toxic (LC50 = 362 µg/ml) than the atlantones enriched fraction (LC50 = 365 µg/ml). LC50 of crude oil was 425 µg/ml and acetonitrile fraction was LC50 = 815 µg/ml. The major constituents, himachalenes and atlantones, likely accounted for the insecticidal action. Present bioassay results revealed the potential for essential oil and different constituents of C. deodara as botanical larvicides for their use in pest management

Complexes of V(III), Oxovanadium(IV) & Oxovanadium(V) with 2-Thio-3-benzoylhydantoin

281-28

Complexes of V(III), Oxovanadium(IV) & Oxovanadium(V) with 2-Thio-3-benzoylhydantoin

281-28

Vesicle formation by amphiphilic 10-alkyl-3-methyl isoalloxazine in aqueous medium

118-124<span style="font-size:12.0pt;font-family: " times="" new="" roman";mso-fareast-font-family:"times="" roman";mso-ansi-language:="" en-in;mso-fareast-language:en-in;mso-bidi-language:ar-sa"="" lang="EN-IN">The synthetic 10-alkyl isoalloxazines have been found to form vesicles in aqueous and binary solvent systems and confirmed by UV -visible, fluorescence, transmission electron microscopy and quasi elastic light scattering experiments. The mean external diameters of vesicles have been calculated for isoalloxazine with different carbon atom chain at position 10 by transmission electron microscopy and quasi elastic laser light scattering. The gel to liquid phase transition of Iiposomes measured by  differential scanning calorimetry shows reproducible endothermic peak which lies well in the range of typical aqueous vesicles</span

Biomimetic oxidation of nicotine with hydrogen Peroxide and 5-ethylflavin mononucleotide perchlorate

294-29

Naturally Occurring Limonene to Cinnamyl-type γ-Butyrolactone Substituted Aldol Condensation Derivatives as Antioxidant Compounds

A method has been developed for the synthesis of γ-butyrolactone substituted cinnamyl type Aldol condensation products under milder proline and triethylamine basic conditions. The antioxidant activity of all the synthesized compounds was assessed using three different assays. The cinnamyl type derivatives of γ-butyrolactone bearing an -OH group in the benzene ring exhibited excellent antioxidant activity

Foliar application of seaweed sap as biostimulant for enhancement of yieldand quality of tomato (<i>Lycopersicon esculentum</i> Mill.)

215-219Effect of Kappaphycus alvarezii sap (seaweed) on growth and yield of tomato was studied in field during kharif season of 2006-07. K. alvarezii sap, applied as a foliar spray (5.0%), increased yield of tomato fruit (60.89%) as compared to control plants sprayed with water, attributed to increase in number of fruits per plant and size of fruit. With application of sap, fruit quality and also macro (13.24-67.50%) and micro (23.84-42.61%) elements content increased over control. Nutrient uptake by fruit and shoot was improved with foliar application of K. alvarezii sap. Plants receiving foliar applications showed resistance to leaf curl, bacterial wilt and fruit borer