266 research outputs found
Toward a Right to Counsel in Civil Cases in New York State: A Report of the New York State Bar Association
Toward a Right to Counsel in Civil Cases in New York State: A Report of the New York State Bar Association
Preserving Aliens\u27 and Migrant Workers\u27 Access to Civil Legal Services: Constitutional and Policy Considerations
Preserving Aliens\u27 and Migrant Workers\u27 Access to Civil Legal Services: Constitutional and Policy Considerations
Panel Discussion: International, National, and Local Perspectives on Civil Right to Counsel
The following is based on a transcript of a panel discussion which took place at An Obvious Truth: Creating an Action Blueprint for a Civil Right to Counsel in New York State, held at Touro Law Center, Central Islip, New York, in March, 2008
A combinatorial TIR1/AFB–Aux/IAA co-receptor system for differential sensing of auxin
The plant hormone auxin regulates virtually every aspect of plant growth and development. Auxin acts by binding the F-box protein transport inhibitor response 1 (TIR1) and promotes the degradation of the AUXIN/INDOLE-3-ACETIC ACID (Aux/IAA) transcriptional repressors. Here we show that efficient auxin binding requires assembly of an auxin co-receptor complex consisting of TIR1 and an Aux/IAA protein. Heterologous experiments in yeast and quantitative IAA binding assays using purified proteins showed that different combinations of TIR1 and Aux/IAA proteins form co-receptor complexes with a wide range of auxin-binding affinities. Auxin affinity seems to be largely determined by the Aux/IAA. As there are 6 TIR1/AUXIN SIGNALING F-BOX proteins (AFBs) and 29 Aux/IAA proteins in Arabidopsis thaliana, combinatorial interactions may result in many co-receptors with distinct auxin-sensing properties. We also demonstrate that the AFB5–Aux/IAA co-receptor selectively binds the auxinic herbicide picloram. This co-receptor system broadens the effective concentration range of the hormone and may contribute to the complexity of auxin response
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