Oral anticoagulation in end-stage CKD and atrial fibrillation

Leading cardiovascular diseases (arterial hypertension, coronary heart disease and diabetes mellitus) are often accompanied by such complications as atrial fibrillation (AF) and chronic kidney disease (CKD). As kidney function worsens, the risk of AF increases. The incidence of AF and CKD ranges from 5:1. At the same time, the risk of developing of end-stage CKD (ESCKD) increases in patients with AF. The combination of AF and ESCKD, on the one hand, increases the risk of thromboembolic complications, and on the other hand, it can cause hemorrhagic complications, which makes it difficult to decide whether to start oral anticoagulant therapy

The Effects of Eprosartan Mesylate and Lercanidipine on Reducing Microalbuminuria in Patients with Nephropathy due to Type 2 Diabetes

In total, 57 patients (31 males and 26 females) with diabetic nephropathy were studied on a comparative basis to observe the renoprotective effectiveness of eprosartan mesylate and lercanidipine. Eprosartan mesylate revealed a higher nephroprotective effect compared with lercanidipine at comparable antihypertensive effects of equivalent doses of both these preparations

Numerical study of dissipative SW/MWCNT-nanofluid coating flow from a stretching wall to a porous medium with shape factor effects

A mathematical model is developed for incompressible steady-state dissipative CNT-aqueous nanofluid boundary layer flow from a stretching sheet to a saturated isotropic porous medium. Three different CNT shapes (spheres, blades and platelets) are considered. Both single-walled (SWCNT) and multi-walled (MWCNT) carbon nanotubes are examined. A Darcy-Brinkman model is adopted for the porous medium and a modified viscous dissipation formulation is considered which features porous media influence in the energy conservation equation. Appropriate expressions are deployed for the CNT-modified nanofluid viscosity, density, specific heat capacity, thermal conductivity and CNT shape factor. Via similarity transformations, th

Growth, characterization, and anti-bacterial activity of l-methionine supplemented with sulphamic acid single crystals

Sulphamic acid (SA) crystals supplemented with l-methionine (LM) were grown at moderate temperatures using a slow evaporation procedure. The powder XRD pattern showed that LM supplemented with SA (LMSA) crystals have an orthorhombic crystal structure. The FTIR studies confirmed the presence of various vibrational modes. Using a UV-Vis spectrometer, the transmittance of LMSA in the UV and visible range was observed, and the band gap of the LMSA was also calculated. The hardness value of LMSA was higher compared to that of pure SA. Photoluminescence emission studies of LMSA pointed out emissions at 491 and 542 nm, which were attributed to the transition from the 5D4 state to 7F6 and 7F5 ground, respectively. LMSA crystals were effective in killing pathogenic bacteria, according to the studies on their anti-bacterial activity

Brownian motion and thermophoretic diffusion impact on Darcy-Forchheimer flow of bioconvective micropolar nanofluid between double disks with Cattaneo-Christov heat flux

The topic of fluid flow through disks is important due to a broad range of its applications in industries, engineering, and scientific fields. The objective of the current article is to analyze the bioconvective micropolar nanofluid flow between the coaxial, parallel, and radially stretching double disks in the occurrence of gyrotactic motile microorganisms with convective thermal boundary conditions. Darcy–Forchheimer medium is considered between the double disks that allow the flow horizontally with additional effects of porosity and friction. The flow is also considered under the impacts of thermal conductivity and thermal radiations. The influence of gyrotactic microorganisms is accommodated through the bioconvection, which increases the strength of thermal transportation. Furthermore, the Cattaneo-Christov heat flux theory is also accounted. The flow model is trans moved into a system of ordinary differential equations (ODEs) utilizing appropriate similarity transformation functions. The bvp4c technique has been used to solve the transformed flow model. The implication of some prominent physical and bioconvection parameters on velocities, microrotation, thermal field, volumetric concentration of nanoparticles, and microorganisms’ fields are presented through graphs and tabular ways. It is observed that the stretching ratio parameter of the disks accelerates the axial and micro rotational velocities of the nanofluid. In contrast, the stretching Reynolds number slows down the radial velocity near the plane’s center. The temperature profile goes high against the Brownian motion, thermal radiation, and thermal conductivity parameters, while an inverse trend has been observed for increasing magnitudes of Prandtl number. The nanoparticles concentration profile is upsurged against the thermophoresis parameter. The density profile of gyrotactic motile microorganisms is de-escalated by the Peclet number and the bioconvection Lewis number. Micropolar parameters cause an increase of couple stresses and a decrement in shear stresses. A comparison with published work is provided under certain limitations to test the validity of numerical scheme accuracy

Effect and investigating of graphene nanoparticles on mechanical, physical properties of polylactic acid polymer

Polylactic acid (PLA) is a linear aliphatic polyester thermoplastic made from renewable sources such as sugar beet and cornstarch. Methods of preparation of polylactic acid are biological and chemical. The advantages of polylactic acid are biocompatibility, easily processing, low energy loss, transparency, high strength, resistance to water and fat penetration and low consumption of carbon dioxide during production. However, polylactic acid has disadvantages such as hydrophobicity, fragility at room temperature, low thermal resistance, slow degradation rate, permeability to gases, lack of active groups and chemical neutrality. To overcome the limitations of polylactic acid, such as low thermal stability and inability to absorb gases, nanoparticles such as graphene are added to improve its properties. Samples were prepared by solution casting method using chloroform as solvent and in thin films. The mechanical, thermal, and structural properties of Polylactic acid pure and Polylactic acid/graphene nanocomposites were studied using tensile Test X-ray diffraction (XRD), Root mean square (RMS) and Differential Scanning Calorimetry (DSC). Also, by exposing the samples to Ultraviolet (UV) rays and then performing the tensile test, the resistance of the produced nanocomposites against Ultraviolet (UV) rays was investigated. With performing the above tests, it was found that by adding graphene nanoparticles to Polylactic acid, the crystallinity decreases and the strength and elongation of graphene particles (0.4% graphene) increase to a certain extent and then decrease. The loss modulus and storage modulus are also increased by the addition of graphene nanoparticles. By comparing the samples exposed to Ultraviolet (UV) rays with other samples, a significant decrease in elongation and a significant increase in modulus of elasticity were observed. In other words, Ultraviolet (UV) rays make Polylactic acid/graphene nanocomposites brittle