Antibacterial effect of green tea against Porphyromonas gingivalis: a literature review

Green tea is regarded as a healthy beverage due to the biological action of polyphenols, specifically catechins. Researchers investigated the inhibitory effects of green tea (Camellia sinensis) plant on both Gram- positive and Gram-negative bacteria. Periodontitis is mainly initiated when dysbiosis of the subgingival microbiome takes place. Porphyromonas gingivalis is one of the key pathogens involved in the initiation and progression of periodontitis when its levels in subgingival biofilm overwhelm the host's immune system. It is the main pathogen that is significantly linked to severe periodontal disease. In this study, details about P. gingivalis including information about its structure, virulence factors were provided. Next, Important points related to green tea, including its active ingredients and antibacterial activity, have been clarified. Finally, the objective of this study was to demonstrate how green tea has antibacterial effects on P. gingivalis

Classic vs. novel antibacterial approaches for eradicating dental biofilm as adjunct to periodontal debridement:an evidence-based overview

Periodontitis is a multifactorial chronic inflammatory disease that affects tooth-supporting soft/hard tissues of the dentition. The dental plaque biofilm is considered as a primary etiological factor in susceptible patients; however, other factors contribute to progression, such as diabetes and smoking. Current management utilizes mechanical biofilm removal as the gold standard of treatment. Antibacterial agents might be indicated in certain conditions as an adjunct to this mechanical approach. However, in view of the growing concern about bacterial resistance, alternative approaches have been investigated. Currently, a range of antimicrobial agents and protocols have been used in clinical management, but these remain largely non-validated. This review aimed to evaluate the efficacy of adjunctive antibiotic use in periodontal management and to compare them to recently suggested alternatives. Evidence from in vitro, observational and clinical trial studies suggests efficacy in the use of adjunctive antimicrobials in patients with grade C periodontitis of young age or where the associated risk factors are inconsistent with the amount of bone loss present. Meanwhile, alternative approaches such as photodynamic therapy, bacteriophage therapy and probiotics showed limited supportive evidence, and more studies are warranted to validate their efficiency