Detection and Forecasting of Islamic Calendar Effects in Time Series Data: Revisited

This paper is an attempt to revisit the pioneering work of Riazuddin and Khan (2002). A complete business cycle has been elapsed (2002-2010) since their study, so there is need to review the results with additional information. This revisited attempt, based on a theoretically specified framework, arrived at similar results and found significant impact of Islamic calendar. The Islamic months of Ramadan and Zilhaj have positive impact on currency holdings and negative impact on deposits. Although stylized facts indicate that consumer prices are significantly higher during Ramadan but econometric investigation rejects the upward exogenous shifts in prices during Ramadan. Therefore, structural relationship analyzed in co-integration framework has shown that inflation is not directly impacted by the Ramadan but indirectly through increase in its determinants. Inflationary tendencies during Ramadan are not due to exogenous increase by producers and retailers but possibly due to demand surge in the wake of redistribution of income. The months of June and December have positive effects on deposits and negative effects on currency in circulation indicating the presence of window dressing. Finally, as seasonal factors have important role in determining economic time series, therefore, ignoring those in monthly time series models will lead to omitted variable bias and inappropriate forecasts.currency in circulation, deposits, cointegration, seasonal factors

Ventral Hernia: Causes and Management

Ventral hernia is the most common type of hernia after inguinal hernias. The term “ventral hernia” creates some confusion, because in most countries of the world, especially in Europe, it is considered as incisional hernia, while in the USA, it is usually considered as hernias of anterior abdominal wall except groin hernias. Daily in the world millions of abdominal surgeries are being performed by both open or conventional and laparoscopic techniques, with 3–20% incidence of incisional. That’s why mainly incisional hernia and its causes, risk factors, and predisposing conditions and management will be discussed in this chapter, though other ventral hernias will be described briefly. The important causes, risk factors [congenital and acquired (patients and postoperative)], and predisposing conditions for ventral hernias will be discussed in detail. The signs and symptoms produced by ventral hernia (incision) will be described initially and later, and how to investigate to confirm the diagnosis and necessary investigations before surgery for different types of patients is described. In managing the ventral hernia, different treatment options are discussed and described, like conservative management, open method, laparoscopic technique, and more advanced robotic technique. After surgery postoperative care of patient and wound is also discussed

Formulation and evaluation of ileo-colonic targeted matrix-mini-tablets of Naproxen for chronotherapeutic treatment of rheumatoid arthritis

AbstractIn this present research work, the aim was to develop ileo-colonic targeted matrix-mini-tablets-filled capsule system of Naproxen for chronotherapeutic treatment of Rheumatoid Arthritis. So Matrix-mini-tablets of Naproxen were prepared using microsomal enzyme dependent and pH-sensitive polymers by direct compression method which were further filled into an empty HPMC capsule. The compatibility was assessed using FT-IR and DSC studies for pure drug, polymers and their physical mixtures. The prepared batches were subjected to physicochemical studies, drug content estimation, in-vitro drug release and stability studies. When FTIR and DSC studies were performed, it was found that there was no interaction between Naproxen and polymers used. The physicochemical properties of all the prepared matrix-mini-tablets batches were found to be in limits. The drug content percentage in the optimized formulation F18 was found to be 99.24±0.10%. Our optimized matrix-mini-tablets-filled-capsule formulation F18 releases Naproxen after a lag time of 2.45±0.97h and 27.30±0.86%, 92.59±0.47%, 99.38±0.69% at the end of 5, 8, 12h respectively. This formulation was also found to be stable as per the guidelines of International Conference on Harmonisation of Technical Requirements of Pharmaceuticals for Human Use. Thus, a novel ileo-colonic targeted delivery system of Naproxen was successfully developed by filling matrix-mini-tablets into an empty HPMC capsule shell for targeting early morning peak symptoms of rheumatoid arthritis

Selection of potent bacterial strain for over-production of PHB by using low cost carbon source for eco-friendly bioplastics

Background: The microbial PHB production is a promising tool for the plastic industry for the synthesis of environmental friendly, biodegradable plastic in contrast to the conventional petro-chemical based non-degradable plastics. The selection of potent bacterial strains, inexpensive carbon source, efficient fermentation and recovery processes are important aspects that were taken into account during this study.Methods: Different bacterial strains i.e. Bacillus Spp, P. putida and P. fluorescens were screened for maximum PHB production. Under media optimization, various carbon and nitrogen sources (alone or in combination) were used to achieve the maximum PHB production. Finally the degradation tests of the PHB sheet were also performed to test its biodegradability potential.Results: Shake flask studies have shown the PHB concentrations upto 7.02, 4.50 and 34.4 mg/g of dry cell mass of P. putida, P. fluorescens and Bacillus Spp. respectively. Almost same results were observed at laboratory scale production of PHB in 10 L fermenter i.e. 6.28, 6.23 and 39.5 mg/g of dry cell mass by P. putida, P. fluorescens and Bacillus Spp. respectively. On the basis of these observations, Bacillus Spp. was chosen for laboratory scale PHB production. Corn steep liquor (4%) was chosen as the best medium to achieve the highest PHB contents. Isolated PHB has shown biodegradation in soil up to 86.7% at 37oC.Conclusion: The Bacillus Spp. Proved to be the best strain for PHB production on only 4% CSL which is cheapest and easily available

Femtosecond Filaments for Standoff Detection of Explosives

In this report, we present our results from various studies to qualitatively discriminate the common military explosives viz. RDX, TNT and HMX in their pure form at a distance of ~6.5 m in standoff mode using femtosecond (fs) filament induced breakdown spectroscopy technique (fs FIBS) together with principal component analysis. A ~30 cm length fs filament obtained by a two-lens configuration was used to interrogate those energetic molecules in the form of pressed pellets (150 mg each). The plasma emissions were collected by a Schmidt-Cassegrain telescope (SCT) from a distance of ~8 m away from the investigation zone. Additionally, a few significant results obtained from the LIBS-based investigations of nitroimidazoles with respect to the standoff distance (~2 m) are discussed. Furthermore, we have also summarised a few important results from our recent investigations of bulk energetic materials in various configurations (including those with fs filaments). The results obtained from various fs FIBS configurations corroborate that the filament generation and its properties, the size and f-number of collection optics influence signal strength in the FIBS technique. These results project the fs FIBS technique as a potential technique for investigations aimed at hazardous materials and harsh environments in the standoff mode