Radiolyse gamma des flavonoïdes (étude de leur réactivité avec les radicaux issus des alcools)

LIMOGES-BU Médecine pharmacie (870852108) / SudocPARIS-BIUP (751062107) / SudocSudocFranceF

Cross-cultural barriers and facilitators of dementia care in Arabic-speaking migrants and refugees: Findings from a narrative scoping review

Background/aims: Given the epidemiological disparities and sociocultural shifts in the context of globalization, providing specialized and appropriate care to people living with dementia has become challenging for various ethnic minorities, particularly Arabic migrants and refugees in their host countries. This scoping review aimed to identify cross-cultural barriers and facilitators in dementia care for this population. Methods: A literature review was conducted in July 2023 following Arksey and O'Malley's (2007) framework. The search strategy included articles published in English that addressed dementia care for Arabic migrants, refugees and their caregivers in their host countries. The search engines included PubMed, Scopus, and the Web of Science. Demographic features, clinical manifestations, factors, barriers, and facilitators of dementia care were summarized. Results: Out of 25 studies have been found, 21 full-text articles were assessed for eligibility. Seven articles were included in this review based on inclusion and exclusion criteria. The principal barriers included lack of health communication (translators and interpreters), clear guidelines and strategies to establish cultural dementia care. Facilitators should include capacity building, training of healthcare practitioners, translators/interpreters about dementia assessment and care, sharing of evidence-based practice, and enabling cross-cultural adaptation of best interventions in dementia care. Conclusion: This study aimed to outline the current state of the literature on dementia care for Arabic migrants and refugees. Effective policymaking, cultural awareness, inclusion, and equity are needed in dementia care to respond culturally and linguistically to the unique characteristics of each Arabic migrant or refugee population

Health-Related Quality of Life of Moroccan COVID-19 Survivors: A Case-Control Study

Background: Research on COVID-19 has mostly focused on transmission, mortality and morbidity associated with the virus. However, less attention has been given to its impact on health-related quality of life (HRQoL) of patients with COVID-19. Therefore, this study aimed to determine the demographic and clinical risk factors associated with COVID-19 and evaluate its impact on the HRQoL of COVID-19 survivors. Methods: A case-control study was carried out between September 2021 and March 2022 on 1105 participants. A total of 354 were COVID-19 survivors and 751 were the control group. The HRQoL was assessed using both EQ-5D-5L and SF-6D generic instruments. Results: The average age of all participants was 56.17 ± 15.46. Older age, urban area, tobacco use, presence of chronic diseases especially type 1 diabetes, kidney and cardiovascular diseases were significantly associated with COVID-19. The COVID-19 survivors had significantly lower HRQoL (EQ-VAS = 50.89) compared to the control group (EQ-VAS = 63.36) (p-value < 0.0001). Pain/ discomfort and anxiety/depression were the most negatively affected by COVID-19 (p-value < 0.0001). Conclusions: The findings from this study could help healthcare professionals and policy makers to better understand the HRQoL sequelae among the COVID-19 survivors and contribute to develop tailored interventions

Lifestyle Habits Determinants of Health-Related Quality of Life in Moroccan College Students

The transition to university is a critical period during which considerable life changes arise. Useful national data to design tailored interventions aimed at promoting health-related quality of life (HRQoL) among Moroccan students are lacking. The present study is aimed at filling this gap by investigating the levels and associated factors of HRQoL among a national sample of Moroccan university students. HRQoL was assessed using the EQ-5D-5L instrument. Data from 2759 university students were collected in a large, cross-sectional, web-based survey. All statistical analyses were conducted using the R software. The EQ-5D-5L findings showed that the majority of students rated level 1 (no problems) and level 2 (slight problems) for the “Mobility”, “Self-Care”, “Usual Activities”, and “Pain/Discomfort” HRQoL dimensions. However, the “Anxiety/Depression” dimension was the exception; more than half (57.1%) of the students were slightly to extremely anxious or depressed. The levels of lifestyle habits were of concern among participants of this study. With respect to sedentary behaviors and physical activity, we found that approximately 80% of participants spent ≥2 h/day on different screen-based sedentary behaviors, and 60% were physically inactive. Lifestyle habits that were found to be associated with HRQoL are sleeping time, physical activity, leisure, hygiene, household activities, homework, and social media time. The multiple regression model explained 93% of the EQ-VAS score variance. The findings could be of great importance for researchers and policymakers interested in promoting health of university students

Association between cervical cancer-related anxiety and depression symptoms and health-related quality of life: A Moroccan cross-sectional study

Introduction: Health-related quality of life (HRQoL) of cervical cancer patients treated by Concurrent Chemoradiation (CCRT) in Morocco is influenced by multiple concomitant factors that affect patients’ post-treatment physical and psychosocial well-being. Therefore, the assessment of post-treatment health related quality of life may help identify groups of patients and risk factors for future interventions for improving post-treatment quality of life. Method: This study aimed at assessing HRQoL and its association to psychological distress of 103 cervical cancer patients treated with CCRT in Morocco. The assessment was performed using the EORTC-QLQ-C30 and the HADS questionnaires. Results: Cervical cancer patients had diminished HRQoL for functional dimensions (''emotional functioning'', “physical functioning” and “role functioning” with averages of 51.78, 54.17, and 58.74, respectively) and high level for symptomatic dimensions with mean scores of 58.90 for “Appetite loss’, 38.83 for “financial difficulties”, 45.31 for “insomnia”, 45.42 for “fatigue”, and 46.28 for “pain”. The assessment of anxiety and depression symptoms showed that the majority of patients had high level of anxiety (62.1%), and depression (61.2%). Emotional functioning, fatigue and insomnia were the main predictors of anxiety disorders in women with cervical cancer. Lower emotional functioning and greater fatigue and insomnia contributed significantly to higher anxiety level. Conclusions: HRQoL and psychological status of Moroccan cervical cancer patients undergoing CCRT were negatively affected. These findings suggest that future patient care policies should include strategies for improving HRQoL, mainly through psychological support and patient education as well as prevention or reduction treatment complications

Among 157 marginal zone lymphomas, DBA.44(CD76) expression is restricted to tumour cells infiltrating the red pulp of the spleen with a diffuse architectural pattern.

International audienc

Relationship between Meteorological and Air Quality Parameters and COVID-19 in Casablanca Region, Morocco

The aim of this study was to investigate the relationship between meteorological parameters, air quality and daily COVID-19 transmission in Morocco. We collected daily data of confirmed COVID-19 cases in the Casablanca region, as well as meteorological parameters (average temperature, wind, relative humidity, precipitation, duration of insolation) and air quality parameters (CO, NO2, 03, SO2, PM10) during the period of 2 March 2020, to 31 December 2020. The General Additive Model (GAM) was used to assess the impact of these parameters on daily cases of COVID-19. A total of 172,746 confirmed cases were reported in the study period. Positive associations were observed between COVID-19 and wind above 20 m/s and humidity above 80%. However, temperatures above 25° were negatively associated with daily cases of COVID-19. PM10 and O3 had a positive effect on the increase in the number of daily confirmed COVID-19 cases, while precipitation had a borderline effect below 25 mm and a negative effect above this value. The findings in this study suggest that significant associations exist between meteorological factors, air quality pollution (PM10) and the transmission of COVID-19. Our findings may help public health authorities better control the spread of COVID-19

COVID-19 Vaccination Acceptance among Health Science Students in Morocco: A Cross-Sectional Study

While students in the health sciences occupy pivotal roles in the Moroccan COVID-19 response and vaccination campaigns, factors associated with COVID-19 vaccine acceptability among students have not been reported. This study aimed to determine the willingness and identify predictive attitudes and beliefs of COVID-19 vaccine acceptance among health science students in Morocco. A cross-sectional, self-administered online questionnaire was conducted among students of the Mohammed VI University of Health Sciences in Casablanca, Morocco in January 2021. In total, 1272 students participated. Univariate and multivariate logistic regression models were used to calculate odds ratios and 95% confidence intervals. Overall, 26.9% of participants reported being willing to receive the COVID-19 vaccine. Between genders, male students were more likely to accept the vaccine. Regarding individual attitudes and beliefs about COVID-19 infection, students with greater confidence in COVID-19 information, and higher perceived likelihood and perceived severity of infection were more likely to be willing to get the vaccine. Concerning a COVID-19 vaccine, students who reported lower levels of perceived harm and higher levels of perceived vaccine effectiveness were more willing to get vaccinated. Our findings help guide future efforts to tailor communication and identify strategies to increase COVID-19 vaccine uptake among students

Acceptability of COVID-19 vaccination among health care workers: a cross-sectional survey in Morocco

Introduction This study aimed to evaluate the acceptability of COVID-19 vaccination among health care workers prior to the start of the COVID-19 vaccination campaign in Morocco. Methods This cross-sectional study was conducted in the Cheikh Khalifa University Hospital of Casablanca-Morocco. Utilizing a web-based platform surveys were distributed over a 3-week period via professional mailing list and social media. Odds ratios and 95% confidence intervals were estimated by using logistic regression models. Results A total of 303 health care workers participated in this study. The results showed a relatively high rate of vaccination acceptability (62.0%) among health care workers included in this study. Participants were more likely to accept the COVID-19 vaccine if they were physician, nurse, or technician (OR 1.79; 95% CI: 1.09–2.95), had high score of confidence in the information circulating about COVID-19 (OR 1.91; 95% CI: 1.36–2.69), or had high score of perceived severity of COVID-19 (OR 1.55; 95% CI: 1.11–2.15). Reasons of hesitation/or refusal of COVID-19 vaccine were fear of the likely side effects of the vaccine for 74.8% of participants, and concern about the effectiveness of the vaccine for 47.8%. Conclusion This study showed a relatively high rate of the COVID-19 vaccination acceptance among health care workers in Morocco. Willingness to be vaccinated was significantly associated with job category, confidence in the information circulating about COVID-19, and perceived severity of COVID-19. These results could be useful in the development of educational interventions to increase the acceptance of COVID-19 vaccine among health care workers in Morocco and similar settings