The odds ratios of serum biochemistry and an autoantibody marker significantly associated with patients classified as having primary biliary cholangitis autoimmune hepatitis overlap syndrome.

<p>The odds ratios of serum biochemistry and an autoantibody marker significantly associated with patients classified as having primary biliary cholangitis autoimmune hepatitis overlap syndrome.</p

Clinical variables, serum biochemistry and autoantibody markers in all patients diagnosed with primary biliary Cholangitis-Autoimmune hepatitis overlap syndrome evaluated in the study.

<p>Clinical variables, serum biochemistry and autoantibody markers in all patients diagnosed with primary biliary Cholangitis-Autoimmune hepatitis overlap syndrome evaluated in the study.</p

Area under the receiver operating characteristic curve (AUROC) values for combinations of variables significantly associated with primary biliary cholangitis autoimmune hepatitis overlap syndrome.

<p>Area under the receiver operating characteristic curve (AUROC) values for combinations of variables significantly associated with primary biliary cholangitis autoimmune hepatitis overlap syndrome.</p

Comparisons of frequencies of autoantibodies in patients with primary biliary cholangitis autoimmune hepatitis overlap syndrome (PBC-AIH OS) and patients with Primary Biliary Cholangitis (PBC) alone.

<p>Comparisons of frequencies of autoantibodies in patients with primary biliary cholangitis autoimmune hepatitis overlap syndrome (PBC-AIH OS) and patients with Primary Biliary Cholangitis (PBC) alone.</p

Receiver Operating Characteristics (ROC) curve utilizing the combination of serum ALT, IgG and presence of <i>Crithidia luciliae</i> assayed anti-dsDNA to identify patients with primary biliary cholangitis autoimmune hepatitis overlap syndrome.

<p>Serum ALT and immunoglobulin G are expressed in units of IU/L and g/L respectively. Anti-dsDNA was evaluated using the <i>Crithidia luciliae</i> immunofluorescence (CLIFT) assay (1:20 dilution). Utilizing all three variables resulted in the highest AUROC value of 0.84.</p