2 research outputs found
Nitrofurantoin and fosfomycin for resistant urinary tract infections: old drugs for emerging problems
Uncomplicated urinary tract infection is one of the most common indications for antibiotic use in
the community. However, the Gram-negative organisms that can cause the infection are becoming
more resistant to antibiotics.
Many multidrug resistant organisms retain susceptibility to two old antibiotics, nitrofurantoin
and fosfomycin. Advantages over newer drugs include their high urinary concentrations and
minimal toxicity.
Fosfomycin is a potential treatment option for patients with uncomplicated urinary tract infection
due to resistant organisms. Nitrofu