Assessment of mediatory role defense styles in the relationship between ego development and marital satisfaction

In recent decades the impact of personality traits on marital relationships has attracted a lot of attention because the character is the most important and the most fundamental issue in marital dissatisfaction. Given the importance of the character , present research studies the mediating role of defense styles in the relationship between marital satisfaction and level of ego developments. Research has shown that correlation can be predicted. For this purpose 200 people were selected by available sampling of Ss ,from teachers of Savogbolag  township. Data from the defense styles (DSQ), sentence completion test (SCT) and marital satisfaction (ENRICH) questionnaires  were collected and the hypothesized model using path analysis methods were used.Results obtained from the correlation and regression analysis showed that ego development indirectly with the mediatory style defense(impact factor:0/21) had significant  impact on  marital satisfaction. we can Therefore prove that the role of the personality and its components, in defense style and ego development can determine level of marital satisfaction and key factors in developing a prevention program are education and health with emphasis on personality

the comparison of biofeed back and kegel exercises methods effectiveness in treatment of urg urinary incontinence in women

The purpose of this study was to determine the effectiveness of biofeedback therapy for urinary incontinence urgency in women, compared with Kegel exercises. In a semi-empirical study, 45 female patients suffering from urinary incontinence urgency, attending Atieh neurology center in 2014 were selected by random sampling and were put in case or control groups randomly. Patients in biofeedback received 5 sessions of 40 minutes electromyographic biofeedback two days a week, while the patients in the other group, attended two 30 minutes session a day of Kegel exercises for 8 weeks. The patients filled up the questionnaire to assess the intensity of incontinence before and after treatment and finally, the data were analyzed through Multivariate analysis of covariance (MANCOVA). The results revealed electromyographic biofeedback therapy was more effective than Kegel exercises (P<0.0001). Furthermore, patients undergoing Biofeedback therapy and Kegel exercises had significant difference with the control group. So, it is concluded that the biofeedback therapy is more effective than Kegel exercises in treating urinary incontinence in women

The Effectiveness of Cognitive Behavior Therapy of Impulse Control on Reduction of Impulsiveness, Crave of Usage and Addiction Severity among Crack Users

Introduction: The present study was done in order to study of the effectiveness of CBT of impulse control on the reduction of impulsiveness, crave of usage and addiction severity of Crack users. Method: In a quasi experimental design 30 Crack addict users who were treating with Methadone in a clinic selected by interview method and consideration of entrance criterions. Then they allocated to two groups (15 subjects for each group) as a witness and experimental groups. The experimental group was under Methadone drug therapy and CBT of impulse control for 8 sessions, and 60 min for each session. But witness group was under Methadone drug therapy and there was not any other intervention. All participants in research were examined before and after treatment by three scales namely: Bart's Impulsiveness Scale, Tifani's Crave Usage, and Addiction Severity Index. MANCOVA was run for analyzing of data. Results: The results showed that significant difference between two groups on impulsiveness subscales crave usage, and addiction severity (except of medical status, job status, law status, and family status). Conclusion: It can say CBT of impulse control can be effective on the reduction of impulsiveness, crave usage and addiction severity in Crack users

Alteration in Frequency and Function of CD4+CD25+ FOXP3+ Regulatory T cells in Patients with Immune Thrombocytopenic Purpura

Immune thrombocytopenic  purpura (ITP) is an autoimmune bleeding disorder characterized by production  of auto-antibodies against platelet antigens. It is obvious that regulatory T cells (Tregs) have a major role in controlling immune homeostasis and preventing autoimmunity. To investigate the frequency and functions of Tregs, twenty ITP patients and twenty age- and sex- matched healthy controls were recruited. The peripheral blood mononuclear cells were isolated and the proportion of Tregs was defined by flow cytometry method. The expression of immune-regulatory markers, cytotoxic T-lymphocyte associated antigen-4 (CTLA-4) and glucocorticoid induced tumor necrosis  factor  receptor  (GITR)  were  also  assessed by  quantitative  Real-time polymerase chain reaction TaqMan method. For evaluation of Treg function, Tregs were enriched and their ability to inhibit proliferation of T cells was measured and levels of immune-regulatory cytokines IL-10 and Transforming growth factor beta (TGF-β) were also measured.Results showed that the frequency of Tregs  and  the  mean  fluorescence  intensity  of  forkhead  box  P3  (FOXP3)  protein  significantly decreased in ITP patients compared to those in healthy controls. In addition, there was a significant reduction  in relative expression of both  CTLA-4 and GITR  mRNA  in ITP  patients (p=0.02 and p=0.006, respectively). The suppressive function of Tregs also diminished in ITP patients compared to controls. Both  IL-10 and TGF-β  cytokines were produced  in lower amounts  in ITP  patients than controls. It  could  be  concluded  that  alteration  in  Treg  frequency and  functional  characteristics might  be responsible for loss of self-tolerance and subsequently destructive immune responses observed in ITP patients

Features of Childhood Acute Myeloid Leukemia in Iran: a Report from Double Center Study

Acute Myeloblastic Leukemia is one of the important malignancies in children. For better managing the prognosis of this disease, there should be enough information about common features of this malignancy. The aim of this study was to evaluate these common features in children with Acute Myeloblastic Leukemia. A total of 104 eligible children less than 15-year-old have been referred from 2007-2011 to two referral centers for childhood malignancies. Basic epidemiological information recorded in checklists for each individual. Analyzes have been done by SPSS version 22. Out of patients, 57 cases were males (54.8%). The male/female ratio was 1.2. The mean age of patients was 6.5 ± 4.3 years. The majority subtypes of patients were M3, M4, non-M3, and M2, respectively. The common molecular abnormalities were t (15;17) and inv (16). Of patients, 19.2% had an early relapse. The mean age of relapse in patients was 6.7 ± 3.9 years. Sixty patients (57.7%) were alive, and 44 cases (42.3%) died during or after therapy. The three years overall survival rate of patients was 42% in this study. According to our data, AML has the same frequency as compared with data from developing countries. But different epidemiological characteristic was a lower rate of three years overall survival in patients. These data may serve the health authorities for more effective environmental and preventive measurements, purposeful allocation of resources for facilitating up-to-date diagnostic and treatment modalities, psychological support programs for respective family members and educational purposes