19 research outputs found
A 20-year satellite-reanalysis-based climatology of extreme precipitation characteristics over the Sinai Peninsula
Extreme precipitation events and associated flash floods caused by synoptic cyclonic systems profoundly impact society and the environment, particularly in arid regions. This study brings forward a satellitereanalysis-based approach to quantify extreme precipitation characteristics over the Sinai Peninsula (SiP) in Egypt from a statistical–synoptic perspective for the period of 2001–2020. With a multi-statistical approach developed in this research, SiP’s wet and dry periods are determined. Using satellite observations of precipitation and a set of derived precipitation indices, we characterize the spatiotemporal variations of extreme rainfall climatologies across the SiP. Then, using the reanalysis datasets, synoptic systems responsible for the occurrence of extreme precipitation events along with the major tracks of cyclones during the wet and dry periods are described. Our results indicate that trends and spatial patterns of the rainfall events across the region are inconsistent in time and space. The highest precipitation percentiles ( ∼ 20 mm per month), frequencies (∼ 15 d per month with rainfall ≥ 10 mm d−1), standard deviations (∼ 9 mm month per month), and monthly ratios (∼ 18 %) are estimated in the northern and northeastern parts of the region during the wet period, especially in early winter; also, a substantial below-average precipitation condition (drier trend) is clearly observed in most parts except for the south. Mediterranean cyclones accompanied by the Red Sea and Persian troughs are responsible for the majority of extreme rainfall events year-round. A remarkable spatial relationship is found between SiP’s rainfall and the atmospheric variables of sea level pressure, wind direction, and vertical velocity. A cyclone-tracking analysis indicates that 125 cyclones (with rainfall ≥ 10 mm d−1) formed within, or transferred to, the Mediterranean basin and precipitated over the SiP during wet periods compared to 31 such cyclones during dry periods. It is estimated around 15 % of cyclones with sufficient rainfall > 40 mm d−1 would be capable of leading to flash floods during the wet period. This study, therefore, sheds new light on the extreme precipitation characteristics over the SiP and its association with dominant synoptic-scale mechanisms over the eastern Mediterranean region
A 20-year satellite-reanalysis-based climatology of extreme precipitation characteristics over the Sinai Peninsula
Extreme precipitation events and associated flash floods caued by the synoptic cyclonic-systems have profound impacts on society and the environment particularly in dry regions. This study brings forward a satellite-reanalysis-based approach to quantify the extreme precipitation characteristics over the Sinai Desert in Egypt, from a statistical-synoptic perspective for the period of 2001–2020. Using the satellite remote-sensing precipitation and a set of climate indices, we characterize the spatiotemporal distribution of extreme rainfall climatologies across the Sinai region. Then, using the reanalysis dataset, the synoptic systems responsible for the occurrence of precipitation events along with the major tracks of cyclones during the wet and dry periods are explored. Our results indicate that the temporal changes and spatial patterns of the precipitation events do not show a homogenous tendency, rather lack of spatiotemporal coherence across the Sinai. Northern parts of the Sinai, unlike other areas, exhibit the highest anomalies (approx. ±45 mm/decade); and the annual rainfall trends indicate a drier-climate in the north at −0.03 mm/decade, while a wetter-climate is observed in the central and southern parts at 0.10 and 0.36 mm/decade, respectively. The Mediterranean cyclones accompanied by the Red Sea -and Persian Troughs are responsible for the majority of extreme rainfall events all-round the year. A remarkable spatial relationship between the Sinai’s rainfall and the atmospheric variables of sea level pressure, wind direction and vertical velocity is found. Furthermore, the cyclone-tracking analysis indicates that 125 and 31 cyclones (rainfall ≥ 10mm/day) either formed within -or transferred to the Mediterranean basin and precipitated over the Sinai during wet and dry periods, respectively; while some (~15 % with rainfall > 40mm/day) being capable of leading to flash flood in the wet period of the region. This study, therefore, sheds new light on the extreme rainfall characteristics and the dominant synoptic mechanisms over the Sinai region in the eastern Mediterranean basin
Evaluation of overall survival and disease-free survival of adjuvant chemotherapy and hormone therapy in patients with breast cancer
Abstract :
Background: This study evaluated the effect of adjuvant chemotherapy and hormone therapy on overall survival and disease-free survival in patients with breast cancer with hormone receptor-positive, HER2-negative tumor without lymph node involvement.
Methods: Breast cancer patients with hormone receptor-positive, HER2-negative, and no lymph node involvement were included in this retrospective cohort study. Patient records were used to collect data on sex, age, time of disease onset, tumor subtype, tumor size, grade, lymphovascular and perineural involvement, ki67, and treatment protocols. Patients were divided into 2 groups: Patients who received both adjuvant chemotherapy and hormonal therapy and patients who received hormonal therapy only. Disease-free survival index (DFS) and overall survival index (OS) were evaluated.
Results: Sixty-seven female patients were enrolled in this study. Of them, 68.2% received both adjuvant chemotherapy and hormonal therapy and 31.6% received hormonal therapy only. During follow-up, recurrences occurred in 8 patients. The 3-year and 5-year DFS were 93.4% and 90%, respectively. The 3-year and 5-year DFS were 94% and 92%, respectively, in patients who received both adjuvant chemotherapy and hormonal therapy, and 91% and 85%, respectively, in patients who received hormonal therapy. None of the factors studied affected the 3-year and 5-year DFS. The 3-year and 5-year DFS OS were 98.6% and 96.9%, respectively
CONCLUSION: Adjuvant chemotherapy in patients with breast cancer with hormone receptor-positive, HER2-negative, and no lymph node involvement compared with similar patients receiving hormone therapy alone had no significant difference in disease-free survival index and overall survival index.
Keywords: breast cancer; disease-free survival index; overall survival inde
A Credit Approach to Measure Inherent Hazards Using the Fire, Explosion and Toxicity Index in the Chemical Process Industry: Case Study of an Iso-max Unit in an Iran Oil Refinery
Objectives: Indices are extensively used for ranking various units of a chemical process industry on the basis of the hazards they pose of risk a fire, explosion and toxicity release.
Methods: This type of ranking enables the professionals to identify the more hazardous units from the less hazardous ones so that greater attention can be paid to the former. The key process subunits in the Iso-max unit were identified based on parameters such as process pressure, temperature and material value. In next step, the main parameters affecting the FETI were identified and estimated, and the Mond FETI index was calculated for each subunit. In addition, the criteria offset measures for each case were identified and their influences were studied.
Results: The results showed that the process route’s potential hazardous characteristics, such as major incidents, were associated with one or more of the following dangerous phenomena: thermal radiation, blast (pressure wave) and ejection of fragments, release of toxic materials and chemical concentration in the air. Intake amount assessments and the corresponding risk of exposure were also produced. By using statistical incident data of the risks of fire, explosion and toxicity, exposure risks can be estimated more realistically as probabilities. This approach is capable of comparing alternative processes to select the one which is inherently safest.
Conclusion: Using this method, the exposure risks in a process can be identified sooner, and proper risk management decisions can be made early in the process development or predesign stages
Climatic comparison of surface urban heat island using satellite remote sensing in Tehran and suburbs
Abstract In this study, we aim to compare the climatic conditions of Surface Urban Heat Island (SUHI) in Tehran and its suburbs using day/night time data from three satellites. A high-resolution Land Surface Temperature (LST) data from MODIS Aqua, Sentinel-3, and Landsat 8 were selected to facilitate this study. The highest values of LST/UHI are observed in downtown Tehran and suburban areas at night. The temperature difference also shows an increase at night in Tehran and the western suburbs, while it decreases during the day. When comparing LST/UHI with altitude in different directions, it is found that urban areas and the south, southeast, southwest, and west suburban areas experience higher temperatures at night. MODIS LST products are more appropriate for checking nighttime SUHI in Tehran's Great area in comparison to other products. Moran's I indicates that the highest positive values occur during seasonal and annual periods at night. The Getis index demonstrates a consistent pattern across all seasons, and this trend persists throughout the year. The seasonal and annual UHI difference between Tehran and its suburbs is 5 °C. The LST diagram reveals that higher temperatures occur during warm months. The temporal NDVI distribution indicates lower NDVI values from June to February and summer to winter. The spatial distribution shows that due to the lack of NDVI index in urban areas, LST/UHI values are higher at night in Tehran compared to the suburbs. UHI is not limited to urban areas but has also spread beyond the city borders. As a result, the highest UHI values are found in downtown Tehran and its southeast, south, southwest, and west suburbs
Spatial patterns and regimes of daily precipitation in Iran in relation to large-scale atmospheric circulation
The relationships between large-scale atmospheric circulation types and seasonal regimes of daily precipitation over Iran are assessed using daily precipitation from a high-resolution gridded dataset provided by the Asian Precipitation-Highly Resolved Observational Data Integration Towards the Evaluation of Water Resources (APHRODITE) Project. Regional spatial modes of daily precipitation variability were identified by S-mode Principal Component Analysis (PCA) with Varimax rotation, applied to the subset of days when at least 10% of all grid-points over Iran received precipitation ≥ 5 mm. The study refers to the period 1961-2004 and is carried out for each season (excluding summer) separately. To characterize the dynamical features associated with each regional precipitation regime (PR), composites of daily atmospheric fields are computed by only averaging days with rotated PCA scores ≥ 1.5 (strong positive phase). In autumn and winter, Iran is divided into five PRs, while four PRs are identified in spring. Results suggest that the spatial distribution of precipitation over Iran is largely governed by the geographical position of both the mid-tropospheric trough over the Middle East and the Arabian anticyclone. In fact, in almost all PRs, the trough, as a pre-conditioning factor, leads to regional-scale ascending motions, whereas the Arabian anticyclone induces low-tropospheric moisture transports from southern water bodies into the cyclonic systems near Iran, triggering rain-generating conditions. © 2011 Royal Meteorological Society
Atmospheric circulation types and winter daily precipitation in Iran
The relationship between daily large-scale atmospheric circulation types (CTs) and wintertime daily precipitation over Iran during the period 1965-2000 is investigated. Twelve atmospheric CTs identified in a previous study, which applied the K-means clustering technique to the rotated principal components (RPCs) of the 500 hPa geopotential height fields, are also considered in this study. The leading spatial modes of daily precipitation variability over Iran are extracted by a PC analysis, with Varimax rotation, applied to the APHRODITE (Asian Precipitation-Highly Resolved Observational Data Integration Towards Evaluation of the Water Resources) gridded precipitation dataset; six Iranian sub-regions with independent precipitation variability are identified. The relationships between the CTs and the daily precipitation are investigated by computing: (1) the spatial patterns of the performance index (PI) for each CT and (2) the cross tabulations between the frequencies of occurrence of the CTs and the RPC scores of the daily precipitation, associated with each of the six sub-regions. Results suggest that two particular CTs affect the precipitation occurrence over most of the country, while the remaining ten provide more regional or negligible contributions to precipitation. The more (less) influencing CTs in each precipitation sub-region are then identified and a characterization of the main large-scale atmospheric features governing the winter precipitation fields is provided
The effect of nanobased irrigants on the root canal dentin microhardness: an ex-vivo study
Abstract Background Given the favorable antimicrobial properties of zinc oxide (ZnONPs), standard silver (AgNPs), and imidazolium-based silver (Im-AgNPs) nanoparticles, this study aimed to evaluate their influence on the microhardness of root canal dentin. Methods In this experimental study, 40 mandibular premolars were decoronated at the cementoenamel junction and longitudinally sectioned into halves to create 80 specimens. They were randomly allocated to 5 groups (n = 16) and irrigated with ZnONPs, AgNPs, Im-AgNPs, NaOCl, or normal saline (as the negative control) for 15 min. The Vickers Hardness Number (VHN) was measured on each root canal third before and after being soaked in irrigants. Statistical analysis was performed using paired t-test, one-way ANOVA, and post hoc Tukey’s test (α = 0.05). Results Im-AgNPs and ZnONPs irrigants improved the microhardness of root dentin, whereas, AgNPs and NaOCl decreased it. ZnONPs yielded the highest VHN at the coronal third (P˂0.001), while the Im-AgNPs provided the highest VHN at the middle and apical thirds (P˂0.001). The AgNPs group showed the lowest VHN at the apical third. Conclusions The irrigants containing Im-AgNPs and ZnONPs significantly enhanced the root dentin microhardness. However, the use of AgNPs resulted in decreased microhardness