Serratia marcescens isolated from neonate patients with septicemia and study of the inhibition effect of Garlic plant extracts compared to antimicrobial agents in Thi Qar province in Iraq

Detection of Extended spectrum beta lactamase (ESBL) enzyme producing bacteria in hospital settings is vital. This study was carried out to determine the distribution of Serratia marcescens that producing ESBL isolated from neonate patients from Al-Imam Al-Hussein hospital at Thi-qar province during a period of nine months from May to December 2020. Out of 100 swabs and samples collected from blood specimens of infant patients, bacterial growth was identified in 22 cultures (22%). The results showed that after treating 22 Serratia isolates with antibiotics, 22 isolates were identified as Seratia producing ESBLs and resistant 100% to antibiotics after incubating the plates cultured with Serratia bacteria for a whole isolates. During this study, garlic extract was used to compare the effect of the extract with isolates that showed high resistance. Where the results showed that there were inhibition rates after treating 22 isolates of Serratia with garlic extract (hexane, alcohol, hexane and alcohol mixtures), where 65% of the samples showed inhibition in different proportions, and 35% showed resistance and inhibition percentages appeared only with alcohol and as for hexane and hexane and alcohol mixtures. No results appeared isolates